6U1V
Crystal structure of acyl-ACP/acyl-CoA dehydrogenase from allylmalonyl-CoA and FK506 biosynthesis, TcsD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| D | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| D | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 37 |
| Details | binding site for residue FDA A 401 |
| Chain | Residue |
| A | LEU83 |
| A | THR200 |
| A | ILE362 |
| A | ILE363 |
| A | GLU364 |
| A | GLY365 |
| A | ASP368 |
| A | VAL369 |
| A | HOH547 |
| A | HOH564 |
| A | HOH578 |
| A | THR116 |
| A | HOH582 |
| A | HOH606 |
| A | HOH621 |
| A | HOH644 |
| A | HOH659 |
| A | HOH675 |
| A | HOH697 |
| A | HOH711 |
| A | HOH749 |
| C | TYR253 |
| A | GLY118 |
| C | LYS257 |
| C | LEU259 |
| C | GLU337 |
| C | MET338 |
| C | PHE339 |
| C | GLY340 |
| C | GLY341 |
| C | HOH712 |
| A | SER119 |
| A | GLY124 |
| A | SER125 |
| A | PHE149 |
| A | SER150 |
| A | THR151 |
| site_id | AC2 |
| Number of Residues | 33 |
| Details | binding site for residue FDA B 401 |
| Chain | Residue |
| B | LEU83 |
| B | THR116 |
| B | LEU117 |
| B | GLY118 |
| B | SER119 |
| B | GLY124 |
| B | SER125 |
| B | PHE149 |
| B | SER150 |
| B | THR151 |
| B | THR200 |
| B | ILE362 |
| B | GLU364 |
| B | GLY365 |
| B | VAL369 |
| B | HOH573 |
| B | HOH615 |
| B | HOH634 |
| B | HOH636 |
| B | HOH655 |
| B | HOH661 |
| B | HOH662 |
| B | HOH704 |
| B | HOH765 |
| D | TYR253 |
| D | LYS257 |
| D | LEU259 |
| D | GLU337 |
| D | MET338 |
| D | PHE339 |
| D | GLY340 |
| D | GLY341 |
| D | HOH688 |
| site_id | AC3 |
| Number of Residues | 37 |
| Details | binding site for residue FDA C 401 |
| Chain | Residue |
| C | HOH583 |
| C | HOH588 |
| C | HOH661 |
| C | HOH675 |
| C | HOH681 |
| C | HOH691 |
| C | HOH694 |
| C | HOH730 |
| A | TYR253 |
| A | LYS257 |
| A | LEU259 |
| A | GLU337 |
| A | MET338 |
| A | PHE339 |
| A | GLY340 |
| A | GLY341 |
| A | HOH680 |
| C | LEU83 |
| C | THR116 |
| C | GLY118 |
| C | SER119 |
| C | GLY124 |
| C | SER125 |
| C | PHE149 |
| C | SER150 |
| C | THR151 |
| C | THR200 |
| C | ILE362 |
| C | ILE363 |
| C | GLU364 |
| C | GLY365 |
| C | ASP368 |
| C | VAL369 |
| C | ASP372 |
| C | HOH523 |
| C | HOH533 |
| C | HOH543 |
| site_id | AC4 |
| Number of Residues | 37 |
| Details | binding site for residue FDA D 401 |
| Chain | Residue |
| B | TYR253 |
| B | LYS257 |
| B | LEU259 |
| B | GLU337 |
| B | MET338 |
| B | PHE339 |
| B | GLY340 |
| B | GLY341 |
| B | HOH702 |
| D | LEU83 |
| D | THR116 |
| D | GLY118 |
| D | SER119 |
| D | GLY124 |
| D | SER125 |
| D | PHE149 |
| D | SER150 |
| D | THR151 |
| D | THR200 |
| D | ILE362 |
| D | ILE363 |
| D | GLU364 |
| D | GLY365 |
| D | ASP368 |
| D | VAL369 |
| D | ASP372 |
| D | HOH560 |
| D | HOH599 |
| D | HOH606 |
| D | HOH617 |
| D | HOH639 |
| D | HOH652 |
| D | HOH653 |
| D | HOH685 |
| D | HOH687 |
| D | HOH704 |
| D | HOH709 |
Functional Information from PROSITE/UniProt
| site_id | PS00073 |
| Number of Residues | 20 |
| Details | ACYL_COA_DH_2 Acyl-CoA dehydrogenases signature 2. EmFGGiGYthDmvigKllrD |
| Chain | Residue | Details |
| A | GLU337-ASP356 |
