6TZY

Crystal Structure of a lipin/Pah Phosphatidic Acid Phosphatase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003713	molecular_function	transcription coactivator activity
A	0005634	cellular_component	nucleus
A	0008195	molecular_function	phosphatidate phosphatase activity
A	0009062	biological_process	fatty acid catabolic process
A	0019432	biological_process	triglyceride biosynthetic process
A	0032869	biological_process	cellular response to insulin stimulus
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0046872	molecular_function	metal ion binding
B	0003713	molecular_function	transcription coactivator activity
B	0005634	cellular_component	nucleus
B	0008195	molecular_function	phosphatidate phosphatase activity
B	0009062	biological_process	fatty acid catabolic process
B	0019432	biological_process	triglyceride biosynthetic process
B	0032869	biological_process	cellular response to insulin stimulus
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0046872	molecular_function	metal ion binding
C	0003713	molecular_function	transcription coactivator activity
C	0005634	cellular_component	nucleus
C	0008195	molecular_function	phosphatidate phosphatase activity
C	0009062	biological_process	fatty acid catabolic process
C	0019432	biological_process	triglyceride biosynthetic process
C	0032869	biological_process	cellular response to insulin stimulus
C	0045944	biological_process	positive regulation of transcription by RNA polymerase II
C	0046872	molecular_function	metal ion binding
D	0003713	molecular_function	transcription coactivator activity
D	0005634	cellular_component	nucleus
D	0008195	molecular_function	phosphatidate phosphatase activity
D	0009062	biological_process	fatty acid catabolic process
D	0019432	biological_process	triglyceride biosynthetic process
D	0032869	biological_process	cellular response to insulin stimulus
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CA A 401

Chain	Residue
A	ASP146
A	LYS244
A	ASN268
A	ASP272
A	HOH515

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site_id	AC2
Number of Residues	4
Details	binding site for residue CA B 400

Chain	Residue
B	LYS67
B	GLU69
C	ASP35
C	HOH504

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site_id	AC3
Number of Residues	5
Details	binding site for residue CA B 401

Chain	Residue
B	ASP146
B	LYS244
B	ASN268
B	ASP272
B	HOH501

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site_id	AC4
Number of Residues	4
Details	binding site for residue CA C 401

Chain	Residue
C	ASP146
C	LYS244
C	ASN268
C	ASP272

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site_id	AC5
Number of Residues	4
Details	binding site for residue CA D 401

Chain	Residue
D	ASP146
D	ASN268
D	ASP272
D	HOH502

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