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6TZ4

CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (right-handed)

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
010015031biological_processprotein transport
020000421cellular_componentautophagosome membrane
020000776cellular_componentkinetochore
020000815cellular_componentESCRT III complex
020001778biological_processplasma membrane repair
020005515molecular_functionprotein binding
020005643cellular_componentnuclear pore
020005765cellular_componentlysosomal membrane
020005768cellular_componentendosome
020005771cellular_componentmultivesicular body
020005828cellular_componentkinetochore microtubule
020005829cellular_componentcytosol
020005886cellular_componentplasma membrane
020006914biological_processautophagy
020006997biological_processnucleus organization
020007034biological_processvacuolar transport
020007080biological_processmitotic metaphase chromosome alignment
020010008cellular_componentendosome membrane
020010824biological_processregulation of centrosome duplication
020015031biological_processprotein transport
020019904molecular_functionprotein domain specific binding
020030117cellular_componentmembrane coat
020030496cellular_componentmidbody
020031468biological_processnuclear membrane reassembly
020031902cellular_componentlate endosome membrane
020032509biological_processendosome transport via multivesicular body sorting pathway
020032585cellular_componentmultivesicular body membrane
020036258biological_processmultivesicular body assembly
020039702biological_processviral budding via host ESCRT complex
020042802molecular_functionidentical protein binding
020043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
020045184biological_processestablishment of protein localization
020045324biological_processlate endosome to vacuole transport
020046761biological_processviral budding from plasma membrane
020051301biological_processcell division
020051469biological_processvesicle fusion with vacuole
020061763biological_processmultivesicular body-lysosome fusion
020061952biological_processmidbody abscission
020070062cellular_componentextracellular exosome
020071985biological_processmultivesicular body sorting pathway
020090148biological_processmembrane fission
020090541molecular_functionMIT domain binding
020097352biological_processautophagosome maturation
021901673biological_processregulation of mitotic spindle assembly
021902774biological_processlate endosome to lysosome transport
021904903biological_processESCRT III complex disassembly
021904930cellular_componentamphisome membrane
A0000421cellular_componentautophagosome membrane
A0000776cellular_componentkinetochore
A0000815cellular_componentESCRT III complex
A0001778biological_processplasma membrane repair
A0005515molecular_functionprotein binding
A0005643cellular_componentnuclear pore
A0005765cellular_componentlysosomal membrane
A0005768cellular_componentendosome
A0005771cellular_componentmultivesicular body
A0005828cellular_componentkinetochore microtubule
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006914biological_processautophagy
A0006997biological_processnucleus organization
A0007034biological_processvacuolar transport
A0007080biological_processmitotic metaphase chromosome alignment
A0010008cellular_componentendosome membrane
A0010824biological_processregulation of centrosome duplication
A0015031biological_processprotein transport
A0019904molecular_functionprotein domain specific binding
A0030117cellular_componentmembrane coat
A0030496cellular_componentmidbody
A0031468biological_processnuclear membrane reassembly
A0031902cellular_componentlate endosome membrane
A0032509biological_processendosome transport via multivesicular body sorting pathway
A0032585cellular_componentmultivesicular body membrane
A0036258biological_processmultivesicular body assembly
A0039702biological_processviral budding via host ESCRT complex
A0042802molecular_functionidentical protein binding
A0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
A0045184biological_processestablishment of protein localization
A0045324biological_processlate endosome to vacuole transport
A0046761biological_processviral budding from plasma membrane
A0051301biological_processcell division
A0051469biological_processvesicle fusion with vacuole
A0061763biological_processmultivesicular body-lysosome fusion
A0061952biological_processmidbody abscission
A0070062cellular_componentextracellular exosome
A0071985biological_processmultivesicular body sorting pathway
A0090148biological_processmembrane fission
A0090541molecular_functionMIT domain binding
A0097352biological_processautophagosome maturation
A1901673biological_processregulation of mitotic spindle assembly
A1902774biological_processlate endosome to lysosome transport
A1904903biological_processESCRT III complex disassembly
A1904930cellular_componentamphisome membrane
AA0015031biological_processprotein transport
AB0015031biological_processprotein transport
B0015031biological_processprotein transport
BA0000421cellular_componentautophagosome membrane
BA0000776cellular_componentkinetochore
BA0000815cellular_componentESCRT III complex
BA0001778biological_processplasma membrane repair
BA0005515molecular_functionprotein binding
BA0005643cellular_componentnuclear pore
BA0005765cellular_componentlysosomal membrane
BA0005768cellular_componentendosome
BA0005771cellular_componentmultivesicular body
BA0005828cellular_componentkinetochore microtubule
BA0005829cellular_componentcytosol
BA0005886cellular_componentplasma membrane
BA0006914biological_processautophagy
BA0006997biological_processnucleus organization
BA0007034biological_processvacuolar transport
BA0007080biological_processmitotic metaphase chromosome alignment
BA0010008cellular_componentendosome membrane
BA0010824biological_processregulation of centrosome duplication
BA0015031biological_processprotein transport
BA0019904molecular_functionprotein domain specific binding
BA0030117cellular_componentmembrane coat
BA0030496cellular_componentmidbody
BA0031468biological_processnuclear membrane reassembly
BA0031902cellular_componentlate endosome membrane
BA0032509biological_processendosome transport via multivesicular body sorting pathway
BA0032585cellular_componentmultivesicular body membrane
BA0036258biological_processmultivesicular body assembly
BA0039702biological_processviral budding via host ESCRT complex
BA0042802molecular_functionidentical protein binding
BA0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
BA0045184biological_processestablishment of protein localization
BA0045324biological_processlate endosome to vacuole transport
BA0046761biological_processviral budding from plasma membrane
BA0051301biological_processcell division
BA0051469biological_processvesicle fusion with vacuole
BA0061763biological_processmultivesicular body-lysosome fusion
BA0061952biological_processmidbody abscission
BA0070062cellular_componentextracellular exosome
BA0071985biological_processmultivesicular body sorting pathway
BA0090148biological_processmembrane fission
BA0090541molecular_functionMIT domain binding
BA0097352biological_processautophagosome maturation
BA1901673biological_processregulation of mitotic spindle assembly
BA1902774biological_processlate endosome to lysosome transport
BA1904903biological_processESCRT III complex disassembly
BA1904930cellular_componentamphisome membrane
BB0000421cellular_componentautophagosome membrane
BB0000776cellular_componentkinetochore
BB0000815cellular_componentESCRT III complex
BB0001778biological_processplasma membrane repair
BB0005515molecular_functionprotein binding
BB0005643cellular_componentnuclear pore
BB0005765cellular_componentlysosomal membrane
BB0005768cellular_componentendosome
BB0005771cellular_componentmultivesicular body
BB0005828cellular_componentkinetochore microtubule
BB0005829cellular_componentcytosol
BB0005886cellular_componentplasma membrane
BB0006914biological_processautophagy
BB0006997biological_processnucleus organization
BB0007034biological_processvacuolar transport
BB0007080biological_processmitotic metaphase chromosome alignment
BB0010008cellular_componentendosome membrane
BB0010824biological_processregulation of centrosome duplication
BB0015031biological_processprotein transport
BB0019904molecular_functionprotein domain specific binding
BB0030117cellular_componentmembrane coat
BB0030496cellular_componentmidbody
BB0031468biological_processnuclear membrane reassembly
BB0031902cellular_componentlate endosome membrane
BB0032509biological_processendosome transport via multivesicular body sorting pathway
BB0032585cellular_componentmultivesicular body membrane
BB0036258biological_processmultivesicular body assembly
BB0039702biological_processviral budding via host ESCRT complex
BB0042802molecular_functionidentical protein binding
BB0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
BB0045184biological_processestablishment of protein localization
BB0045324biological_processlate endosome to vacuole transport
BB0046761biological_processviral budding from plasma membrane
BB0051301biological_processcell division
BB0051469biological_processvesicle fusion with vacuole
BB0061763biological_processmultivesicular body-lysosome fusion
BB0061952biological_processmidbody abscission
BB0070062cellular_componentextracellular exosome
BB0071985biological_processmultivesicular body sorting pathway
BB0090148biological_processmembrane fission
BB0090541molecular_functionMIT domain binding
BB0097352biological_processautophagosome maturation
BB1901673biological_processregulation of mitotic spindle assembly
BB1902774biological_processlate endosome to lysosome transport
BB1904903biological_processESCRT III complex disassembly
BB1904930cellular_componentamphisome membrane
C0000421cellular_componentautophagosome membrane
C0000776cellular_componentkinetochore
C0000815cellular_componentESCRT III complex
C0001778biological_processplasma membrane repair
C0005515molecular_functionprotein binding
C0005643cellular_componentnuclear pore
C0005765cellular_componentlysosomal membrane
C0005768cellular_componentendosome
C0005771cellular_componentmultivesicular body
C0005828cellular_componentkinetochore microtubule
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0006914biological_processautophagy
C0006997biological_processnucleus organization
C0007034biological_processvacuolar transport
C0007080biological_processmitotic metaphase chromosome alignment
C0010008cellular_componentendosome membrane
C0010824biological_processregulation of centrosome duplication
C0015031biological_processprotein transport
C0019904molecular_functionprotein domain specific binding
C0030117cellular_componentmembrane coat
C0030496cellular_componentmidbody
C0031468biological_processnuclear membrane reassembly
C0031902cellular_componentlate endosome membrane
C0032509biological_processendosome transport via multivesicular body sorting pathway
C0032585cellular_componentmultivesicular body membrane
C0036258biological_processmultivesicular body assembly
C0039702biological_processviral budding via host ESCRT complex
C0042802molecular_functionidentical protein binding
C0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
C0045184biological_processestablishment of protein localization
C0045324biological_processlate endosome to vacuole transport
C0046761biological_processviral budding from plasma membrane
C0051301biological_processcell division
C0051469biological_processvesicle fusion with vacuole
C0061763biological_processmultivesicular body-lysosome fusion
C0061952biological_processmidbody abscission
C0070062cellular_componentextracellular exosome
C0071985biological_processmultivesicular body sorting pathway
C0090148biological_processmembrane fission
C0090541molecular_functionMIT domain binding
C0097352biological_processautophagosome maturation
C1901673biological_processregulation of mitotic spindle assembly
C1902774biological_processlate endosome to lysosome transport
C1904903biological_processESCRT III complex disassembly
C1904930cellular_componentamphisome membrane
CA0015031biological_processprotein transport
CB0015031biological_processprotein transport
D0015031biological_processprotein transport
DA0000421cellular_componentautophagosome membrane
DA0000776cellular_componentkinetochore
DA0000815cellular_componentESCRT III complex
DA0001778biological_processplasma membrane repair
DA0005515molecular_functionprotein binding
DA0005643cellular_componentnuclear pore
DA0005765cellular_componentlysosomal membrane
DA0005768cellular_componentendosome
DA0005771cellular_componentmultivesicular body
DA0005828cellular_componentkinetochore microtubule
DA0005829cellular_componentcytosol
DA0005886cellular_componentplasma membrane
DA0006914biological_processautophagy
DA0006997biological_processnucleus organization
DA0007034biological_processvacuolar transport
DA0007080biological_processmitotic metaphase chromosome alignment
DA0010008cellular_componentendosome membrane
DA0010824biological_processregulation of centrosome duplication
DA0015031biological_processprotein transport
DA0019904molecular_functionprotein domain specific binding
DA0030117cellular_componentmembrane coat
DA0030496cellular_componentmidbody
DA0031468biological_processnuclear membrane reassembly
DA0031902cellular_componentlate endosome membrane
DA0032509biological_processendosome transport via multivesicular body sorting pathway
DA0032585cellular_componentmultivesicular body membrane
DA0036258biological_processmultivesicular body assembly
DA0039702biological_processviral budding via host ESCRT complex
DA0042802molecular_functionidentical protein binding
DA0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
DA0045184biological_processestablishment of protein localization
DA0045324biological_processlate endosome to vacuole transport
DA0046761biological_processviral budding from plasma membrane
DA0051301biological_processcell division
DA0051469biological_processvesicle fusion with vacuole
DA0061763biological_processmultivesicular body-lysosome fusion
DA0061952biological_processmidbody abscission
DA0070062cellular_componentextracellular exosome
DA0071985biological_processmultivesicular body sorting pathway
DA0090148biological_processmembrane fission
DA0090541molecular_functionMIT domain binding
DA0097352biological_processautophagosome maturation
DA1901673biological_processregulation of mitotic spindle assembly
DA1902774biological_processlate endosome to lysosome transport
DA1904903biological_processESCRT III complex disassembly
DA1904930cellular_componentamphisome membrane
DB0000421cellular_componentautophagosome membrane
DB0000776cellular_componentkinetochore
DB0000815cellular_componentESCRT III complex
DB0001778biological_processplasma membrane repair
DB0005515molecular_functionprotein binding
DB0005643cellular_componentnuclear pore
DB0005765cellular_componentlysosomal membrane
DB0005768cellular_componentendosome
DB0005771cellular_componentmultivesicular body
DB0005828cellular_componentkinetochore microtubule
DB0005829cellular_componentcytosol
DB0005886cellular_componentplasma membrane
DB0006914biological_processautophagy
DB0006997biological_processnucleus organization
DB0007034biological_processvacuolar transport
DB0007080biological_processmitotic metaphase chromosome alignment
DB0010008cellular_componentendosome membrane
DB0010824biological_processregulation of centrosome duplication
DB0015031biological_processprotein transport
DB0019904molecular_functionprotein domain specific binding
DB0030117cellular_componentmembrane coat
DB0030496cellular_componentmidbody
DB0031468biological_processnuclear membrane reassembly
DB0031902cellular_componentlate endosome membrane
DB0032509biological_processendosome transport via multivesicular body sorting pathway
DB0032585cellular_componentmultivesicular body membrane
DB0036258biological_processmultivesicular body assembly
DB0039702biological_processviral budding via host ESCRT complex
DB0042802molecular_functionidentical protein binding
DB0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
DB0045184biological_processestablishment of protein localization
DB0045324biological_processlate endosome to vacuole transport
DB0046761biological_processviral budding from plasma membrane
DB0051301biological_processcell division
DB0051469biological_processvesicle fusion with vacuole
DB0061763biological_processmultivesicular body-lysosome fusion
DB0061952biological_processmidbody abscission
DB0070062cellular_componentextracellular exosome
DB0071985biological_processmultivesicular body sorting pathway
DB0090148biological_processmembrane fission
DB0090541molecular_functionMIT domain binding
DB0097352biological_processautophagosome maturation
DB1901673biological_processregulation of mitotic spindle assembly
DB1902774biological_processlate endosome to lysosome transport
DB1904903biological_processESCRT III complex disassembly
DB1904930cellular_componentamphisome membrane
E0000421cellular_componentautophagosome membrane
E0000776cellular_componentkinetochore
E0000815cellular_componentESCRT III complex
E0001778biological_processplasma membrane repair
E0005515molecular_functionprotein binding
E0005643cellular_componentnuclear pore
E0005765cellular_componentlysosomal membrane
E0005768cellular_componentendosome
E0005771cellular_componentmultivesicular body
E0005828cellular_componentkinetochore microtubule
E0005829cellular_componentcytosol
E0005886cellular_componentplasma membrane
E0006914biological_processautophagy
E0006997biological_processnucleus organization
E0007034biological_processvacuolar transport
E0007080biological_processmitotic metaphase chromosome alignment
E0010008cellular_componentendosome membrane
E0010824biological_processregulation of centrosome duplication
E0015031biological_processprotein transport
E0019904molecular_functionprotein domain specific binding
E0030117cellular_componentmembrane coat
E0030496cellular_componentmidbody
E0031468biological_processnuclear membrane reassembly
E0031902cellular_componentlate endosome membrane
E0032509biological_processendosome transport via multivesicular body sorting pathway
E0032585cellular_componentmultivesicular body membrane
E0036258biological_processmultivesicular body assembly
E0039702biological_processviral budding via host ESCRT complex
E0042802molecular_functionidentical protein binding
E0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
E0045184biological_processestablishment of protein localization
E0045324biological_processlate endosome to vacuole transport
E0046761biological_processviral budding from plasma membrane
E0051301biological_processcell division
E0051469biological_processvesicle fusion with vacuole
E0061763biological_processmultivesicular body-lysosome fusion
E0061952biological_processmidbody abscission
E0070062cellular_componentextracellular exosome
E0071985biological_processmultivesicular body sorting pathway
E0090148biological_processmembrane fission
E0090541molecular_functionMIT domain binding
E0097352biological_processautophagosome maturation
E1901673biological_processregulation of mitotic spindle assembly
E1902774biological_processlate endosome to lysosome transport
E1904903biological_processESCRT III complex disassembly
E1904930cellular_componentamphisome membrane
EA0015031biological_processprotein transport
EB0015031biological_processprotein transport
F0015031biological_processprotein transport
FA0000421cellular_componentautophagosome membrane
FA0000776cellular_componentkinetochore
FA0000815cellular_componentESCRT III complex
FA0001778biological_processplasma membrane repair
FA0005515molecular_functionprotein binding
FA0005643cellular_componentnuclear pore
FA0005765cellular_componentlysosomal membrane
FA0005768cellular_componentendosome
FA0005771cellular_componentmultivesicular body
FA0005828cellular_componentkinetochore microtubule
FA0005829cellular_componentcytosol
FA0005886cellular_componentplasma membrane
FA0006914biological_processautophagy
FA0006997biological_processnucleus organization
FA0007034biological_processvacuolar transport
FA0007080biological_processmitotic metaphase chromosome alignment
FA0010008cellular_componentendosome membrane
FA0010824biological_processregulation of centrosome duplication
FA0015031biological_processprotein transport
FA0019904molecular_functionprotein domain specific binding
FA0030117cellular_componentmembrane coat
FA0030496cellular_componentmidbody
FA0031468biological_processnuclear membrane reassembly
FA0031902cellular_componentlate endosome membrane
FA0032509biological_processendosome transport via multivesicular body sorting pathway
FA0032585cellular_componentmultivesicular body membrane
FA0036258biological_processmultivesicular body assembly
FA0039702biological_processviral budding via host ESCRT complex
FA0042802molecular_functionidentical protein binding
FA0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
FA0045184biological_processestablishment of protein localization
FA0045324biological_processlate endosome to vacuole transport
FA0046761biological_processviral budding from plasma membrane
FA0051301biological_processcell division
FA0051469biological_processvesicle fusion with vacuole
FA0061763biological_processmultivesicular body-lysosome fusion
FA0061952biological_processmidbody abscission
FA0070062cellular_componentextracellular exosome
FA0071985biological_processmultivesicular body sorting pathway
FA0090148biological_processmembrane fission
FA0090541molecular_functionMIT domain binding
FA0097352biological_processautophagosome maturation
FA1901673biological_processregulation of mitotic spindle assembly
FA1902774biological_processlate endosome to lysosome transport
FA1904903biological_processESCRT III complex disassembly
FA1904930cellular_componentamphisome membrane
FB0000421cellular_componentautophagosome membrane
FB0000776cellular_componentkinetochore
FB0000815cellular_componentESCRT III complex
FB0001778biological_processplasma membrane repair
FB0005515molecular_functionprotein binding
FB0005643cellular_componentnuclear pore
FB0005765cellular_componentlysosomal membrane
FB0005768cellular_componentendosome
FB0005771cellular_componentmultivesicular body
FB0005828cellular_componentkinetochore microtubule
FB0005829cellular_componentcytosol
FB0005886cellular_componentplasma membrane
FB0006914biological_processautophagy
FB0006997biological_processnucleus organization
FB0007034biological_processvacuolar transport
FB0007080biological_processmitotic metaphase chromosome alignment
FB0010008cellular_componentendosome membrane
FB0010824biological_processregulation of centrosome duplication
FB0015031biological_processprotein transport
FB0019904molecular_functionprotein domain specific binding
FB0030117cellular_componentmembrane coat
FB0030496cellular_componentmidbody
FB0031468biological_processnuclear membrane reassembly
FB0031902cellular_componentlate endosome membrane
FB0032509biological_processendosome transport via multivesicular body sorting pathway
FB0032585cellular_componentmultivesicular body membrane
FB0036258biological_processmultivesicular body assembly
FB0039702biological_processviral budding via host ESCRT complex
FB0042802molecular_functionidentical protein binding
FB0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
FB0045184biological_processestablishment of protein localization
FB0045324biological_processlate endosome to vacuole transport
FB0046761biological_processviral budding from plasma membrane
FB0051301biological_processcell division
FB0051469biological_processvesicle fusion with vacuole
FB0061763biological_processmultivesicular body-lysosome fusion
FB0061952biological_processmidbody abscission
FB0070062cellular_componentextracellular exosome
FB0071985biological_processmultivesicular body sorting pathway
FB0090148biological_processmembrane fission
FB0090541molecular_functionMIT domain binding
FB0097352biological_processautophagosome maturation
FB1901673biological_processregulation of mitotic spindle assembly
FB1902774biological_processlate endosome to lysosome transport
FB1904903biological_processESCRT III complex disassembly
FB1904930cellular_componentamphisome membrane
G0000421cellular_componentautophagosome membrane
G0000776cellular_componentkinetochore
G0000815cellular_componentESCRT III complex
G0001778biological_processplasma membrane repair
G0005515molecular_functionprotein binding
G0005643cellular_componentnuclear pore
G0005765cellular_componentlysosomal membrane
G0005768cellular_componentendosome
G0005771cellular_componentmultivesicular body
G0005828cellular_componentkinetochore microtubule
G0005829cellular_componentcytosol
G0005886cellular_componentplasma membrane
G0006914biological_processautophagy
G0006997biological_processnucleus organization
G0007034biological_processvacuolar transport
G0007080biological_processmitotic metaphase chromosome alignment
G0010008cellular_componentendosome membrane
G0010824biological_processregulation of centrosome duplication
G0015031biological_processprotein transport
G0019904molecular_functionprotein domain specific binding
G0030117cellular_componentmembrane coat
G0030496cellular_componentmidbody
G0031468biological_processnuclear membrane reassembly
G0031902cellular_componentlate endosome membrane
G0032509biological_processendosome transport via multivesicular body sorting pathway
G0032585cellular_componentmultivesicular body membrane
G0036258biological_processmultivesicular body assembly
G0039702biological_processviral budding via host ESCRT complex
G0042802molecular_functionidentical protein binding
G0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
G0045184biological_processestablishment of protein localization
G0045324biological_processlate endosome to vacuole transport
G0046761biological_processviral budding from plasma membrane
G0051301biological_processcell division
G0051469biological_processvesicle fusion with vacuole
G0061763biological_processmultivesicular body-lysosome fusion
G0061952biological_processmidbody abscission
G0070062cellular_componentextracellular exosome
G0071985biological_processmultivesicular body sorting pathway
G0090148biological_processmembrane fission
G0090541molecular_functionMIT domain binding
G0097352biological_processautophagosome maturation
G1901673biological_processregulation of mitotic spindle assembly
G1902774biological_processlate endosome to lysosome transport
G1904903biological_processESCRT III complex disassembly
G1904930cellular_componentamphisome membrane
GA0015031biological_processprotein transport
GB0015031biological_processprotein transport
H0015031biological_processprotein transport
HA0000421cellular_componentautophagosome membrane
HA0000776cellular_componentkinetochore
HA0000815cellular_componentESCRT III complex
HA0001778biological_processplasma membrane repair
HA0005515molecular_functionprotein binding
HA0005643cellular_componentnuclear pore
HA0005765cellular_componentlysosomal membrane
HA0005768cellular_componentendosome
HA0005771cellular_componentmultivesicular body
HA0005828cellular_componentkinetochore microtubule
HA0005829cellular_componentcytosol
HA0005886cellular_componentplasma membrane
HA0006914biological_processautophagy
HA0006997biological_processnucleus organization
HA0007034biological_processvacuolar transport
HA0007080biological_processmitotic metaphase chromosome alignment
HA0010008cellular_componentendosome membrane
HA0010824biological_processregulation of centrosome duplication
HA0015031biological_processprotein transport
HA0019904molecular_functionprotein domain specific binding
HA0030117cellular_componentmembrane coat
HA0030496cellular_componentmidbody
HA0031468biological_processnuclear membrane reassembly
HA0031902cellular_componentlate endosome membrane
HA0032509biological_processendosome transport via multivesicular body sorting pathway
HA0032585cellular_componentmultivesicular body membrane
HA0036258biological_processmultivesicular body assembly
HA0039702biological_processviral budding via host ESCRT complex
HA0042802molecular_functionidentical protein binding
HA0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
HA0045184biological_processestablishment of protein localization
HA0045324biological_processlate endosome to vacuole transport
HA0046761biological_processviral budding from plasma membrane
HA0051301biological_processcell division
HA0051469biological_processvesicle fusion with vacuole
HA0061763biological_processmultivesicular body-lysosome fusion
HA0061952biological_processmidbody abscission
HA0070062cellular_componentextracellular exosome
HA0071985biological_processmultivesicular body sorting pathway
HA0090148biological_processmembrane fission
HA0090541molecular_functionMIT domain binding
HA0097352biological_processautophagosome maturation
HA1901673biological_processregulation of mitotic spindle assembly
HA1902774biological_processlate endosome to lysosome transport
HA1904903biological_processESCRT III complex disassembly
HA1904930cellular_componentamphisome membrane
HB0000421cellular_componentautophagosome membrane
HB0000776cellular_componentkinetochore
HB0000815cellular_componentESCRT III complex
HB0001778biological_processplasma membrane repair
HB0005515molecular_functionprotein binding
HB0005643cellular_componentnuclear pore
HB0005765cellular_componentlysosomal membrane
HB0005768cellular_componentendosome
HB0005771cellular_componentmultivesicular body
HB0005828cellular_componentkinetochore microtubule
HB0005829cellular_componentcytosol
HB0005886cellular_componentplasma membrane
HB0006914biological_processautophagy
HB0006997biological_processnucleus organization
HB0007034biological_processvacuolar transport
HB0007080biological_processmitotic metaphase chromosome alignment
HB0010008cellular_componentendosome membrane
HB0010824biological_processregulation of centrosome duplication
HB0015031biological_processprotein transport
HB0019904molecular_functionprotein domain specific binding
HB0030117cellular_componentmembrane coat
HB0030496cellular_componentmidbody
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Q0000815cellular_componentESCRT III complex
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Q0005515molecular_functionprotein binding
Q0005643cellular_componentnuclear pore
Q0005765cellular_componentlysosomal membrane
Q0005768cellular_componentendosome
Q0005771cellular_componentmultivesicular body
Q0005828cellular_componentkinetochore microtubule
Q0005829cellular_componentcytosol
Q0005886cellular_componentplasma membrane
Q0006914biological_processautophagy
Q0006997biological_processnucleus organization
Q0007034biological_processvacuolar transport
Q0007080biological_processmitotic metaphase chromosome alignment
Q0010008cellular_componentendosome membrane
Q0010824biological_processregulation of centrosome duplication
Q0015031biological_processprotein transport
Q0019904molecular_functionprotein domain specific binding
Q0030117cellular_componentmembrane coat
Q0030496cellular_componentmidbody
Q0031468biological_processnuclear membrane reassembly
Q0031902cellular_componentlate endosome membrane
Q0032509biological_processendosome transport via multivesicular body sorting pathway
Q0032585cellular_componentmultivesicular body membrane
Q0036258biological_processmultivesicular body assembly
Q0039702biological_processviral budding via host ESCRT complex
Q0042802molecular_functionidentical protein binding
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Q0045184biological_processestablishment of protein localization
Q0045324biological_processlate endosome to vacuole transport
Q0046761biological_processviral budding from plasma membrane
Q0051301biological_processcell division
Q0051469biological_processvesicle fusion with vacuole
Q0061763biological_processmultivesicular body-lysosome fusion
Q0061952biological_processmidbody abscission
Q0070062cellular_componentextracellular exosome
Q0071985biological_processmultivesicular body sorting pathway
Q0090148biological_processmembrane fission
Q0090541molecular_functionMIT domain binding
Q0097352biological_processautophagosome maturation
Q1901673biological_processregulation of mitotic spindle assembly
Q1902774biological_processlate endosome to lysosome transport
Q1904903biological_processESCRT III complex disassembly
Q1904930cellular_componentamphisome membrane
QA0015031biological_processprotein transport
QB0015031biological_processprotein transport
R0015031biological_processprotein transport
RA0000421cellular_componentautophagosome membrane
RA0000776cellular_componentkinetochore
RA0000815cellular_componentESCRT III complex
RA0001778biological_processplasma membrane repair
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RA0005643cellular_componentnuclear pore
RA0005765cellular_componentlysosomal membrane
RA0005768cellular_componentendosome
RA0005771cellular_componentmultivesicular body
RA0005828cellular_componentkinetochore microtubule
RA0005829cellular_componentcytosol
RA0005886cellular_componentplasma membrane
RA0006914biological_processautophagy
RA0006997biological_processnucleus organization
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RA0007080biological_processmitotic metaphase chromosome alignment
RA0010008cellular_componentendosome membrane
RA0010824biological_processregulation of centrosome duplication
RA0015031biological_processprotein transport
RA0019904molecular_functionprotein domain specific binding
RA0030117cellular_componentmembrane coat
RA0030496cellular_componentmidbody
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RA0031902cellular_componentlate endosome membrane
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RA0032585cellular_componentmultivesicular body membrane
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RA0039702biological_processviral budding via host ESCRT complex
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RA0046761biological_processviral budding from plasma membrane
RA0051301biological_processcell division
RA0051469biological_processvesicle fusion with vacuole
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RA0061952biological_processmidbody abscission
RA0070062cellular_componentextracellular exosome
RA0071985biological_processmultivesicular body sorting pathway
RA0090148biological_processmembrane fission
RA0090541molecular_functionMIT domain binding
RA0097352biological_processautophagosome maturation
RA1901673biological_processregulation of mitotic spindle assembly
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RA1904903biological_processESCRT III complex disassembly
RA1904930cellular_componentamphisome membrane
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RB0000776cellular_componentkinetochore
RB0000815cellular_componentESCRT III complex
RB0001778biological_processplasma membrane repair
RB0005515molecular_functionprotein binding
RB0005643cellular_componentnuclear pore
RB0005765cellular_componentlysosomal membrane
RB0005768cellular_componentendosome
RB0005771cellular_componentmultivesicular body
RB0005828cellular_componentkinetochore microtubule
RB0005829cellular_componentcytosol
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RB0007034biological_processvacuolar transport
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RB0010008cellular_componentendosome membrane
RB0010824biological_processregulation of centrosome duplication
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RB0019904molecular_functionprotein domain specific binding
RB0030117cellular_componentmembrane coat
RB0030496cellular_componentmidbody
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RB0031902cellular_componentlate endosome membrane
RB0032509biological_processendosome transport via multivesicular body sorting pathway
RB0032585cellular_componentmultivesicular body membrane
RB0036258biological_processmultivesicular body assembly
RB0039702biological_processviral budding via host ESCRT complex
RB0042802molecular_functionidentical protein binding
RB0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
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RB0045324biological_processlate endosome to vacuole transport
RB0046761biological_processviral budding from plasma membrane
RB0051301biological_processcell division
RB0051469biological_processvesicle fusion with vacuole
RB0061763biological_processmultivesicular body-lysosome fusion
RB0061952biological_processmidbody abscission
RB0070062cellular_componentextracellular exosome
RB0071985biological_processmultivesicular body sorting pathway
RB0090148biological_processmembrane fission
RB0090541molecular_functionMIT domain binding
RB0097352biological_processautophagosome maturation
RB1901673biological_processregulation of mitotic spindle assembly
RB1902774biological_processlate endosome to lysosome transport
RB1904903biological_processESCRT III complex disassembly
RB1904930cellular_componentamphisome membrane
S0000421cellular_componentautophagosome membrane
S0000776cellular_componentkinetochore
S0000815cellular_componentESCRT III complex
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S0005643cellular_componentnuclear pore
S0005765cellular_componentlysosomal membrane
S0005768cellular_componentendosome
S0005771cellular_componentmultivesicular body
S0005828cellular_componentkinetochore microtubule
S0005829cellular_componentcytosol
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S0010008cellular_componentendosome membrane
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S0031902cellular_componentlate endosome membrane
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S0039702biological_processviral budding via host ESCRT complex
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S0046761biological_processviral budding from plasma membrane
S0051301biological_processcell division
S0051469biological_processvesicle fusion with vacuole
S0061763biological_processmultivesicular body-lysosome fusion
S0061952biological_processmidbody abscission
S0070062cellular_componentextracellular exosome
S0071985biological_processmultivesicular body sorting pathway
S0090148biological_processmembrane fission
S0090541molecular_functionMIT domain binding
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S1901673biological_processregulation of mitotic spindle assembly
S1902774biological_processlate endosome to lysosome transport
S1904903biological_processESCRT III complex disassembly
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SA0015031biological_processprotein transport
SB0015031biological_processprotein transport
T0015031biological_processprotein transport
TA0000421cellular_componentautophagosome membrane
TA0000776cellular_componentkinetochore
TA0000815cellular_componentESCRT III complex
TA0001778biological_processplasma membrane repair
TA0005515molecular_functionprotein binding
TA0005643cellular_componentnuclear pore
TA0005765cellular_componentlysosomal membrane
TA0005768cellular_componentendosome
TA0005771cellular_componentmultivesicular body
TA0005828cellular_componentkinetochore microtubule
TA0005829cellular_componentcytosol
TA0005886cellular_componentplasma membrane
TA0006914biological_processautophagy
TA0006997biological_processnucleus organization
TA0007034biological_processvacuolar transport
TA0007080biological_processmitotic metaphase chromosome alignment
TA0010008cellular_componentendosome membrane
TA0010824biological_processregulation of centrosome duplication
TA0015031biological_processprotein transport
TA0019904molecular_functionprotein domain specific binding
TA0030117cellular_componentmembrane coat
TA0030496cellular_componentmidbody
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TA0031902cellular_componentlate endosome membrane
TA0032509biological_processendosome transport via multivesicular body sorting pathway
TA0032585cellular_componentmultivesicular body membrane
TA0036258biological_processmultivesicular body assembly
TA0039702biological_processviral budding via host ESCRT complex
TA0042802molecular_functionidentical protein binding
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TA0045324biological_processlate endosome to vacuole transport
TA0046761biological_processviral budding from plasma membrane
TA0051301biological_processcell division
TA0051469biological_processvesicle fusion with vacuole
TA0061763biological_processmultivesicular body-lysosome fusion
TA0061952biological_processmidbody abscission
TA0070062cellular_componentextracellular exosome
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TA0090148biological_processmembrane fission
TA0090541molecular_functionMIT domain binding
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TA1901673biological_processregulation of mitotic spindle assembly
TA1902774biological_processlate endosome to lysosome transport
TA1904903biological_processESCRT III complex disassembly
TA1904930cellular_componentamphisome membrane
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V0000421cellular_componentautophagosome membrane
V0000776cellular_componentkinetochore
V0000815cellular_componentESCRT III complex
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V0005515molecular_functionprotein binding
V0005643cellular_componentnuclear pore
V0005765cellular_componentlysosomal membrane
V0005768cellular_componentendosome
V0005771cellular_componentmultivesicular body
V0005828cellular_componentkinetochore microtubule
V0005829cellular_componentcytosol
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V0010008cellular_componentendosome membrane
V0010824biological_processregulation of centrosome duplication
V0015031biological_processprotein transport
V0019904molecular_functionprotein domain specific binding
V0030117cellular_componentmembrane coat
V0030496cellular_componentmidbody
V0031468biological_processnuclear membrane reassembly
V0031902cellular_componentlate endosome membrane
V0032509biological_processendosome transport via multivesicular body sorting pathway
V0032585cellular_componentmultivesicular body membrane
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V0039702biological_processviral budding via host ESCRT complex
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V0045324biological_processlate endosome to vacuole transport
V0046761biological_processviral budding from plasma membrane
V0051301biological_processcell division
V0051469biological_processvesicle fusion with vacuole
V0061763biological_processmultivesicular body-lysosome fusion
V0061952biological_processmidbody abscission
V0070062cellular_componentextracellular exosome
V0071985biological_processmultivesicular body sorting pathway
V0090148biological_processmembrane fission
V0090541molecular_functionMIT domain binding
V0097352biological_processautophagosome maturation
V1901673biological_processregulation of mitotic spindle assembly
V1902774biological_processlate endosome to lysosome transport
V1904903biological_processESCRT III complex disassembly
V1904930cellular_componentamphisome membrane
VA0000421cellular_componentautophagosome membrane
VA0000776cellular_componentkinetochore
VA0000815cellular_componentESCRT III complex
VA0001778biological_processplasma membrane repair
VA0005515molecular_functionprotein binding
VA0005643cellular_componentnuclear pore
VA0005765cellular_componentlysosomal membrane
VA0005768cellular_componentendosome
VA0005771cellular_componentmultivesicular body
VA0005828cellular_componentkinetochore microtubule
VA0005829cellular_componentcytosol
VA0005886cellular_componentplasma membrane
VA0006914biological_processautophagy
VA0006997biological_processnucleus organization
VA0007034biological_processvacuolar transport
VA0007080biological_processmitotic metaphase chromosome alignment
VA0010008cellular_componentendosome membrane
VA0010824biological_processregulation of centrosome duplication
VA0015031biological_processprotein transport
VA0019904molecular_functionprotein domain specific binding
VA0030117cellular_componentmembrane coat
VA0030496cellular_componentmidbody
VA0031468biological_processnuclear membrane reassembly
VA0031902cellular_componentlate endosome membrane
VA0032509biological_processendosome transport via multivesicular body sorting pathway
VA0032585cellular_componentmultivesicular body membrane
VA0036258biological_processmultivesicular body assembly
VA0039702biological_processviral budding via host ESCRT complex
VA0042802molecular_functionidentical protein binding
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VA0045184biological_processestablishment of protein localization
VA0045324biological_processlate endosome to vacuole transport
VA0046761biological_processviral budding from plasma membrane
VA0051301biological_processcell division
VA0051469biological_processvesicle fusion with vacuole
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VA0061952biological_processmidbody abscission
VA0070062cellular_componentextracellular exosome
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VA0090148biological_processmembrane fission
VA0090541molecular_functionMIT domain binding
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VA1901673biological_processregulation of mitotic spindle assembly
VA1902774biological_processlate endosome to lysosome transport
VA1904903biological_processESCRT III complex disassembly
VA1904930cellular_componentamphisome membrane
W0015031biological_processprotein transport
WA0015031biological_processprotein transport
X0000421cellular_componentautophagosome membrane
X0000776cellular_componentkinetochore
X0000815cellular_componentESCRT III complex
X0001778biological_processplasma membrane repair
X0005515molecular_functionprotein binding
X0005643cellular_componentnuclear pore
X0005765cellular_componentlysosomal membrane
X0005768cellular_componentendosome
X0005771cellular_componentmultivesicular body
X0005828cellular_componentkinetochore microtubule
X0005829cellular_componentcytosol
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X0010008cellular_componentendosome membrane
X0010824biological_processregulation of centrosome duplication
X0015031biological_processprotein transport
X0019904molecular_functionprotein domain specific binding
X0030117cellular_componentmembrane coat
X0030496cellular_componentmidbody
X0031468biological_processnuclear membrane reassembly
X0031902cellular_componentlate endosome membrane
X0032509biological_processendosome transport via multivesicular body sorting pathway
X0032585cellular_componentmultivesicular body membrane
X0036258biological_processmultivesicular body assembly
X0039702biological_processviral budding via host ESCRT complex
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X0045324biological_processlate endosome to vacuole transport
X0046761biological_processviral budding from plasma membrane
X0051301biological_processcell division
X0051469biological_processvesicle fusion with vacuole
X0061763biological_processmultivesicular body-lysosome fusion
X0061952biological_processmidbody abscission
X0070062cellular_componentextracellular exosome
X0071985biological_processmultivesicular body sorting pathway
X0090148biological_processmembrane fission
X0090541molecular_functionMIT domain binding
X0097352biological_processautophagosome maturation
X1901673biological_processregulation of mitotic spindle assembly
X1902774biological_processlate endosome to lysosome transport
X1904903biological_processESCRT III complex disassembly
X1904930cellular_componentamphisome membrane
XA0000421cellular_componentautophagosome membrane
XA0000776cellular_componentkinetochore
XA0000815cellular_componentESCRT III complex
XA0001778biological_processplasma membrane repair
XA0005515molecular_functionprotein binding
XA0005643cellular_componentnuclear pore
XA0005765cellular_componentlysosomal membrane
XA0005768cellular_componentendosome
XA0005771cellular_componentmultivesicular body
XA0005828cellular_componentkinetochore microtubule
XA0005829cellular_componentcytosol
XA0005886cellular_componentplasma membrane
XA0006914biological_processautophagy
XA0006997biological_processnucleus organization
XA0007034biological_processvacuolar transport
XA0007080biological_processmitotic metaphase chromosome alignment
XA0010008cellular_componentendosome membrane
XA0010824biological_processregulation of centrosome duplication
XA0015031biological_processprotein transport
XA0019904molecular_functionprotein domain specific binding
XA0030117cellular_componentmembrane coat
XA0030496cellular_componentmidbody
XA0031468biological_processnuclear membrane reassembly
XA0031902cellular_componentlate endosome membrane
XA0032509biological_processendosome transport via multivesicular body sorting pathway
XA0032585cellular_componentmultivesicular body membrane
XA0036258biological_processmultivesicular body assembly
XA0039702biological_processviral budding via host ESCRT complex
XA0042802molecular_functionidentical protein binding
XA0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
XA0045184biological_processestablishment of protein localization
XA0045324biological_processlate endosome to vacuole transport
XA0046761biological_processviral budding from plasma membrane
XA0051301biological_processcell division
XA0051469biological_processvesicle fusion with vacuole
XA0061763biological_processmultivesicular body-lysosome fusion
XA0061952biological_processmidbody abscission
XA0070062cellular_componentextracellular exosome
XA0071985biological_processmultivesicular body sorting pathway
XA0090148biological_processmembrane fission
XA0090541molecular_functionMIT domain binding
XA0097352biological_processautophagosome maturation
XA1901673biological_processregulation of mitotic spindle assembly
XA1902774biological_processlate endosome to lysosome transport
XA1904903biological_processESCRT III complex disassembly
XA1904930cellular_componentamphisome membrane
Y0015031biological_processprotein transport
YA0015031biological_processprotein transport
Z0000421cellular_componentautophagosome membrane
Z0000776cellular_componentkinetochore
Z0000815cellular_componentESCRT III complex
Z0001778biological_processplasma membrane repair
Z0005515molecular_functionprotein binding
Z0005643cellular_componentnuclear pore
Z0005765cellular_componentlysosomal membrane
Z0005768cellular_componentendosome
Z0005771cellular_componentmultivesicular body
Z0005828cellular_componentkinetochore microtubule
Z0005829cellular_componentcytosol
Z0005886cellular_componentplasma membrane
Z0006914biological_processautophagy
Z0006997biological_processnucleus organization
Z0007034biological_processvacuolar transport
Z0007080biological_processmitotic metaphase chromosome alignment
Z0010008cellular_componentendosome membrane
Z0010824biological_processregulation of centrosome duplication
Z0015031biological_processprotein transport
Z0019904molecular_functionprotein domain specific binding
Z0030117cellular_componentmembrane coat
Z0030496cellular_componentmidbody
Z0031468biological_processnuclear membrane reassembly
Z0031902cellular_componentlate endosome membrane
Z0032509biological_processendosome transport via multivesicular body sorting pathway
Z0032585cellular_componentmultivesicular body membrane
Z0036258biological_processmultivesicular body assembly
Z0039702biological_processviral budding via host ESCRT complex
Z0042802molecular_functionidentical protein binding
Z0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Z0045184biological_processestablishment of protein localization
Z0045324biological_processlate endosome to vacuole transport
Z0046761biological_processviral budding from plasma membrane
Z0051301biological_processcell division
Z0051469biological_processvesicle fusion with vacuole
Z0061763biological_processmultivesicular body-lysosome fusion
Z0061952biological_processmidbody abscission
Z0070062cellular_componentextracellular exosome
Z0071985biological_processmultivesicular body sorting pathway
Z0090148biological_processmembrane fission
Z0090541molecular_functionMIT domain binding
Z0097352biological_processautophagosome maturation
Z1901673biological_processregulation of mitotic spindle assembly
Z1902774biological_processlate endosome to lysosome transport
Z1904903biological_processESCRT III complex disassembly
Z1904930cellular_componentamphisome membrane
ZA0000421cellular_componentautophagosome membrane
ZA0000776cellular_componentkinetochore
ZA0000815cellular_componentESCRT III complex
ZA0001778biological_processplasma membrane repair
ZA0005515molecular_functionprotein binding
ZA0005643cellular_componentnuclear pore
ZA0005765cellular_componentlysosomal membrane
ZA0005768cellular_componentendosome
ZA0005771cellular_componentmultivesicular body
ZA0005828cellular_componentkinetochore microtubule
ZA0005829cellular_componentcytosol
ZA0005886cellular_componentplasma membrane
ZA0006914biological_processautophagy
ZA0006997biological_processnucleus organization
ZA0007034biological_processvacuolar transport
ZA0007080biological_processmitotic metaphase chromosome alignment
ZA0010008cellular_componentendosome membrane
ZA0010824biological_processregulation of centrosome duplication
ZA0015031biological_processprotein transport
ZA0019904molecular_functionprotein domain specific binding
ZA0030117cellular_componentmembrane coat
ZA0030496cellular_componentmidbody
ZA0031468biological_processnuclear membrane reassembly
ZA0031902cellular_componentlate endosome membrane
ZA0032509biological_processendosome transport via multivesicular body sorting pathway
ZA0032585cellular_componentmultivesicular body membrane
ZA0036258biological_processmultivesicular body assembly
ZA0039702biological_processviral budding via host ESCRT complex
ZA0042802molecular_functionidentical protein binding
ZA0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
ZA0045184biological_processestablishment of protein localization
ZA0045324biological_processlate endosome to vacuole transport
ZA0046761biological_processviral budding from plasma membrane
ZA0051301biological_processcell division
ZA0051469biological_processvesicle fusion with vacuole
ZA0061763biological_processmultivesicular body-lysosome fusion
ZA0061952biological_processmidbody abscission
ZA0070062cellular_componentextracellular exosome
ZA0071985biological_processmultivesicular body sorting pathway
ZA0090148biological_processmembrane fission
ZA0090541molecular_functionMIT domain binding
ZA0097352biological_processautophagosome maturation
ZA1901673biological_processregulation of mitotic spindle assembly
ZA1902774biological_processlate endosome to lysosome transport
ZA1904903biological_processESCRT III complex disassembly
ZA1904930cellular_componentamphisome membrane
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues864
DetailsRegion: {"description":"Interaction with IST1"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues792
DetailsCoiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues360
DetailsMotif: {"description":"MIT-interacting motif"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues36
DetailsModified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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