Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008800 | molecular_function | beta-lactamase activity |
A | 0017001 | biological_process | antibiotic catabolic process |
A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
A | 0046677 | biological_process | response to antibiotic |
B | 0008800 | molecular_function | beta-lactamase activity |
B | 0017001 | biological_process | antibiotic catabolic process |
B | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
B | 0046677 | biological_process | response to antibiotic |
C | 0008800 | molecular_function | beta-lactamase activity |
C | 0017001 | biological_process | antibiotic catabolic process |
C | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
C | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | binding site for residue GOL A 901 |
Chain | Residue |
A | PRO107 |
A | LYS111 |
A | TYR129 |
site_id | AC2 |
Number of Residues | 9 |
Details | binding site for residue FMT A 902 |
Chain | Residue |
A | THR237 |
A | FMT903 |
A | HOH1122 |
A | SER70 |
A | SER130 |
A | ARG220 |
A | LYS234 |
A | THR235 |
A | GLY236 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue FMT A 903 |
Chain | Residue |
A | CYS69 |
A | SER70 |
A | ASN170 |
A | GLY236 |
A | THR237 |
A | FMT902 |
A | HOH1020 |
A | HOH1083 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue ACT A 904 |
Chain | Residue |
A | ARG65 |
A | GLY175 |
A | ASP176 |
A | PRO177 |
A | HOH1064 |
A | HOH1170 |
C | ASP101 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue ACT A 905 |
Chain | Residue |
A | ILE155 |
A | GLY156 |
A | ASP157 |
A | THR189 |
A | THR192 |
A | HOH1002 |
site_id | AC6 |
Number of Residues | 6 |
Details | binding site for residue FMT A 906 |
Chain | Residue |
A | ASP63 |
A | VAL159 |
A | HOH1004 |
A | HOH1023 |
A | HOH1035 |
A | HOH1053 |
site_id | AC7 |
Number of Residues | 9 |
Details | binding site for residue GOL A 907 |
Chain | Residue |
A | GLY98 |
A | GLU100 |
A | HOH1081 |
A | HOH1107 |
B | ARG43 |
B | GLU64 |
B | ARG65 |
B | HOH1549 |
B | HOH1621 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue FMT A 908 |
Chain | Residue |
A | GLU100 |
A | ASP101 |
A | HOH1059 |
B | GLY175 |
B | PRO177 |
site_id | AC9 |
Number of Residues | 4 |
Details | binding site for residue ACT A 909 |
Chain | Residue |
A | ARG161 |
A | PRO177 |
A | HOH1159 |
C | TRP165 |
site_id | AD1 |
Number of Residues | 5 |
Details | binding site for residue NA A 910 |
Chain | Residue |
A | TYR97 |
A | VAL113 |
A | HOH1081 |
A | HOH1124 |
B | HOH1668 |
site_id | AD2 |
Number of Residues | 10 |
Details | binding site for residue 6NT A 911 |
Chain | Residue |
A | VAL48 |
A | ASP229 |
A | VAL250 |
A | PRO252 |
A | ILE259 |
A | LEU261 |
A | VAL286 |
A | TRP290 |
A | HOH1071 |
B | ARG284 |
site_id | AD3 |
Number of Residues | 3 |
Details | binding site for residue FMT B 1401 |
Chain | Residue |
A | TRP165 |
B | ARG161 |
B | HOH1511 |
site_id | AD4 |
Number of Residues | 8 |
Details | binding site for residue GOL B 1402 |
Chain | Residue |
B | ILE155 |
B | GLY156 |
B | ASP157 |
B | ALA185 |
B | ALA188 |
B | THR189 |
B | THR192 |
B | HOH1526 |
site_id | AD5 |
Number of Residues | 6 |
Details | binding site for residue FMT B 1403 |
Chain | Residue |
B | CYS69 |
B | SER70 |
B | ASN170 |
B | GLY236 |
B | THR237 |
B | FMT1404 |
site_id | AD6 |
Number of Residues | 8 |
Details | binding site for residue FMT B 1404 |
Chain | Residue |
B | SER70 |
B | SER130 |
B | ARG220 |
B | LYS234 |
B | THR235 |
B | GLY236 |
B | THR237 |
B | FMT1403 |
site_id | AD7 |
Number of Residues | 4 |
Details | binding site for residue FMT B 1405 |
Chain | Residue |
B | HIS293 |
B | HOH1592 |
B | ARG55 |
B | ALA289 |
site_id | AD8 |
Number of Residues | 3 |
Details | binding site for residue FMT B 1406 |
Chain | Residue |
B | ASP104 |
B | PRO167 |
B | HOH1612 |
site_id | AD9 |
Number of Residues | 5 |
Details | binding site for residue GOL B 1407 |
Chain | Residue |
B | HIS241 |
B | GLY242 |
B | GLU267 |
B | SER268 |
B | GLN269 |
site_id | AE1 |
Number of Residues | 7 |
Details | binding site for residue ACT B 1408 |
Chain | Residue |
B | THR96 |
B | HOH1520 |
B | HOH1566 |
B | HOH1604 |
C | ASP63 |
C | VAL159 |
C | HOH822 |
site_id | AE2 |
Number of Residues | 4 |
Details | binding site for residue FMT B 1409 |
Chain | Residue |
A | VAL113 |
A | GLY114 |
B | PRO201 |
B | HOH1615 |
site_id | AE3 |
Number of Residues | 3 |
Details | binding site for residue FMT B 1410 |
Chain | Residue |
B | VAL108 |
B | LYS111 |
B | TYR129 |
site_id | AE4 |
Number of Residues | 5 |
Details | binding site for residue FMT B 1411 |
Chain | Residue |
A | GLN32 |
A | HIS292 |
B | ALA288 |
B | HIS292 |
B | HOH1626 |
site_id | AE5 |
Number of Residues | 4 |
Details | binding site for residue FMT B 1412 |
Chain | Residue |
B | GLY143 |
B | TRP165 |
C | ARG161 |
C | ASP163 |
site_id | AE6 |
Number of Residues | 10 |
Details | binding site for residue 6NT B 1413 |
Chain | Residue |
A | ARG284 |
B | ASP229 |
B | VAL250 |
B | ARG256 |
B | ILE259 |
B | LEU261 |
B | VAL286 |
B | VAL287 |
B | TRP290 |
B | HOH1565 |
site_id | AE7 |
Number of Residues | 4 |
Details | binding site for residue GOL C 701 |
Chain | Residue |
B | GLU140 |
B | TRP165 |
C | ARG161 |
C | PRO177 |
site_id | AE8 |
Number of Residues | 7 |
Details | binding site for residue FMT C 702 |
Chain | Residue |
C | CYS69 |
C | SER70 |
C | ASN170 |
C | GLY236 |
C | THR237 |
C | FMT703 |
C | HOH825 |
site_id | AE9 |
Number of Residues | 8 |
Details | binding site for residue FMT C 703 |
Chain | Residue |
C | SER70 |
C | SER130 |
C | ARG220 |
C | LYS234 |
C | THR235 |
C | GLY236 |
C | THR237 |
C | FMT702 |
site_id | AF1 |
Number of Residues | 7 |
Details | binding site for residue FMT C 704 |
Chain | Residue |
A | ARG65 |
A | HOH1159 |
C | ASP101 |
C | LEU137 |
C | GLU140 |
C | HOH850 |
C | HOH852 |
site_id | AF2 |
Number of Residues | 3 |
Details | binding site for residue FMT C 705 |
Chain | Residue |
C | ASP228 |
C | ALA280 |
C | ARG284 |
site_id | AF3 |
Number of Residues | 5 |
Details | binding site for residue ACT C 706 |
Chain | Residue |
C | ILE155 |
C | THR189 |
C | THR192 |
C | HOH801 |
C | HOH927 |
site_id | AF4 |
Number of Residues | 10 |
Details | binding site for residue 6NT C 707 |
Chain | Residue |
C | VAL48 |
C | ASP229 |
C | VAL250 |
C | ILE259 |
C | LEU261 |
C | ARG284 |
C | VAL286 |
C | VAL287 |
C | TRP290 |
C | HOH831 |
Functional Information from PROSITE/UniProt
site_id | PS00146 |
Number of Residues | 16 |
Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. FpMCSTfKallAAAVL |
Chain | Residue | Details |
A | PHE66-LEU81 | |