6TXJ
Crystal structure of thermotoga maritima A42V E65D Ferritin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004322 | molecular_function | ferroxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006826 | biological_process | iron ion transport |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0008198 | molecular_function | ferrous iron binding |
| A | 0008199 | molecular_function | ferric iron binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004322 | molecular_function | ferroxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006826 | biological_process | iron ion transport |
| B | 0006879 | biological_process | intracellular iron ion homeostasis |
| B | 0008198 | molecular_function | ferrous iron binding |
| B | 0008199 | molecular_function | ferric iron binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004322 | molecular_function | ferroxidase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006826 | biological_process | iron ion transport |
| C | 0006879 | biological_process | intracellular iron ion homeostasis |
| C | 0008198 | molecular_function | ferrous iron binding |
| C | 0008199 | molecular_function | ferric iron binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004322 | molecular_function | ferroxidase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006826 | biological_process | iron ion transport |
| D | 0006879 | biological_process | intracellular iron ion homeostasis |
| D | 0008198 | molecular_function | ferrous iron binding |
| D | 0008199 | molecular_function | ferric iron binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0004322 | molecular_function | ferroxidase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006826 | biological_process | iron ion transport |
| E | 0006879 | biological_process | intracellular iron ion homeostasis |
| E | 0008198 | molecular_function | ferrous iron binding |
| E | 0008199 | molecular_function | ferric iron binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0042802 | molecular_function | identical protein binding |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0004322 | molecular_function | ferroxidase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006826 | biological_process | iron ion transport |
| F | 0006879 | biological_process | intracellular iron ion homeostasis |
| F | 0008198 | molecular_function | ferrous iron binding |
| F | 0008199 | molecular_function | ferric iron binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0042802 | molecular_function | identical protein binding |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0004322 | molecular_function | ferroxidase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005829 | cellular_component | cytosol |
| G | 0006826 | biological_process | iron ion transport |
| G | 0006879 | biological_process | intracellular iron ion homeostasis |
| G | 0008198 | molecular_function | ferrous iron binding |
| G | 0008199 | molecular_function | ferric iron binding |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0042802 | molecular_function | identical protein binding |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0004322 | molecular_function | ferroxidase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005829 | cellular_component | cytosol |
| H | 0006826 | biological_process | iron ion transport |
| H | 0006879 | biological_process | intracellular iron ion homeostasis |
| H | 0008198 | molecular_function | ferrous iron binding |
| H | 0008199 | molecular_function | ferric iron binding |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0042802 | molecular_function | identical protein binding |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | HIS43 |
| A | LYS46 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 202 |
| Chain | Residue |
| A | ARG18 |
| A | HOH312 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 203 |
| Chain | Residue |
| A | SER111 |
| A | HIS116 |
| A | VAL119 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 204 |
| Chain | Residue |
| A | ASN81 |
| A | PRO79 |
| A | SER80 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 205 |
| Chain | Residue |
| A | TRP44 |
| A | GLN135 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 206 |
| Chain | Residue |
| A | GLU97 |
| A | THR100 |
| A | GLU133 |
| F | VAL3 |
| F | ARG66 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 207 |
| Chain | Residue |
| A | PHE154 |
| A | ASP157 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue FE A 208 |
| Chain | Residue |
| A | GLU19 |
| A | GLU52 |
| A | HIS55 |
| A | HOH304 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| B | GLY84 |
| B | ILE85 |
| B | LYS86 |
| B | HOH303 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 202 |
| Chain | Residue |
| A | GLN149 |
| A | SER151 |
| B | GLN149 |
| B | SER151 |
| D | GLN149 |
| D | SER151 |
| E | ASN147 |
| E | GLN149 |
| E | SER151 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 203 |
| Chain | Residue |
| B | SER111 |
| B | HIS116 |
| B | VAL119 |
| B | HOH317 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 204 |
| Chain | Residue |
| B | HIS43 |
| B | LYS46 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 205 |
| Chain | Residue |
| B | PRO79 |
| B | SER80 |
| B | ASN81 |
| B | HOH301 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 206 |
| Chain | Residue |
| B | VAL3 |
| B | ARG66 |
| B | GLU97 |
| B | GLU133 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 207 |
| Chain | Residue |
| B | SER5 |
| B | GLU6 |
| B | LYS7 |
| B | HOH322 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 208 |
| Chain | Residue |
| B | ARG18 |
| B | PHE98 |
| B | HOH305 |
| B | HOH314 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 209 |
| Chain | Residue |
| B | TRP44 |
| B | GLN135 |
| B | GLU138 |
| B | ILE139 |
| B | TYR159 |
| B | LEU160 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 210 |
| Chain | Residue |
| B | ASP157 |
| D | TYR159 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue LFA B 211 |
| Chain | Residue |
| A | ILE20 |
| A | SER23 |
| A | GLN50 |
| A | MET57 |
| B | SER23 |
| B | GLN50 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue FE B 212 |
| Chain | Residue |
| B | GLU19 |
| B | GLU52 |
| B | HIS55 |
| B | HOH306 |
| B | HOH312 |
| B | HOH319 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 201 |
| Chain | Residue |
| C | ARG18 |
| C | PHE98 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 202 |
| Chain | Residue |
| C | SER111 |
| C | HIS116 |
| C | VAL119 |
| E | HOH306 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 203 |
| Chain | Residue |
| C | HIS43 |
| C | LYS46 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue FE C 205 |
| Chain | Residue |
| C | GLU19 |
| C | GLU52 |
| C | HIS55 |
| C | HOH302 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 201 |
| Chain | Residue |
| D | GLY84 |
| D | ILE85 |
| D | LYS86 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 202 |
| Chain | Residue |
| D | SER111 |
| D | HIS116 |
| D | VAL119 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 203 |
| Chain | Residue |
| D | HIS43 |
| D | LYS46 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 204 |
| Chain | Residue |
| D | SER80 |
| D | ASN81 |
| D | PRO79 |
| site_id | AF2 |
| Number of Residues | 1 |
| Details | binding site for residue GOL D 205 |
| Chain | Residue |
| D | ARG18 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue FE D 206 |
| Chain | Residue |
| D | GLU19 |
| D | GLU52 |
| D | HIS55 |
| D | HOH301 |
| site_id | AF4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 E 201 |
| Chain | Residue |
| E | ARG18 |
| E | PHE98 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 E 202 |
| Chain | Residue |
| E | SER111 |
| E | HIS116 |
| E | VAL119 |
| E | HOH306 |
| G | SO4202 |
| site_id | AF6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 E 203 |
| Chain | Residue |
| E | HIS43 |
| E | HOH309 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue FE E 204 |
| Chain | Residue |
| E | GLU19 |
| E | GLU52 |
| E | HIS55 |
| E | HOH301 |
| E | HOH308 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 F 201 |
| Chain | Residue |
| F | ASN83 |
| F | GLY84 |
| F | ILE85 |
| F | LYS86 |
| G | ASN147 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 F 202 |
| Chain | Residue |
| F | SER111 |
| F | HIS116 |
| F | VAL119 |
| F | HOH302 |
| site_id | AG1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 F 203 |
| Chain | Residue |
| F | HIS43 |
| F | LYS46 |
| site_id | AG2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 204 |
| Chain | Residue |
| F | PRO79 |
| F | SER80 |
| F | ASN81 |
| site_id | AG3 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 F 205 |
| Chain | Residue |
| C | GLN149 |
| C | SER151 |
| F | GLN149 |
| F | SER151 |
| G | GLN149 |
| G | SER151 |
| H | GLN149 |
| H | SER151 |
| site_id | AG4 |
| Number of Residues | 5 |
| Details | binding site for residue LFA F 206 |
| Chain | Residue |
| E | SER23 |
| F | SER23 |
| F | TYR24 |
| F | GLN50 |
| F | MET57 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue FE F 207 |
| Chain | Residue |
| F | GLU19 |
| F | GLU52 |
| F | HIS55 |
| F | GLN129 |
| site_id | AG6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 G 201 |
| Chain | Residue |
| G | GLY84 |
| G | ILE85 |
| G | LYS86 |
| site_id | AG7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 G 202 |
| Chain | Residue |
| E | SO4202 |
| G | SER111 |
| G | HIS116 |
| G | VAL119 |
| site_id | AG8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 G 203 |
| Chain | Residue |
| G | HIS43 |
| G | LYS46 |
| site_id | AG9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 G 204 |
| Chain | Residue |
| G | PRO79 |
| G | SER80 |
| G | ASN81 |
| site_id | AH1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 G 205 |
| Chain | Residue |
| G | TRP44 |
| G | GLN135 |
| G | LEU160 |
| site_id | AH2 |
| Number of Residues | 4 |
| Details | binding site for residue LFA G 206 |
| Chain | Residue |
| G | SER23 |
| G | TYR24 |
| H | SER23 |
| H | GLN50 |
| site_id | AH3 |
| Number of Residues | 4 |
| Details | binding site for residue FE G 207 |
| Chain | Residue |
| G | GLU19 |
| G | GLU52 |
| G | HIS55 |
| G | HOH301 |
| site_id | AH4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 H 201 |
| Chain | Residue |
| H | GLY84 |
| H | ILE85 |
| H | LYS86 |
| site_id | AH5 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 H 202 |
| Chain | Residue |
| H | HIS43 |
| site_id | AH6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 H 203 |
| Chain | Residue |
| H | PRO79 |
| H | SER80 |
| H | ASN81 |
| site_id | AH7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 H 204 |
| Chain | Residue |
| H | SER5 |
| H | GLU6 |
| site_id | AH8 |
| Number of Residues | 4 |
| Details | binding site for residue FE H 205 |
| Chain | Residue |
| H | GLU19 |
| H | GLU52 |
| H | HIS55 |
| H | HOH301 |
| site_id | AH9 |
| Number of Residues | 11 |
| Details | binding site for Di-peptide LFA C 204 and GLN C 50 |
| Chain | Residue |
| C | SER23 |
| C | LYS46 |
| C | LYS47 |
| C | GLN48 |
| C | ALA49 |
| C | GLU51 |
| C | GLU52 |
| C | LEU53 |
| C | THR54 |
| D | SER23 |
| D | GLN50 |
