6TWN
Crystal structure of Talin1 R7R8 in complex with CDK1 (206-223)
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 1701 |
| Chain | Residue |
| B | LYS1415 |
| B | HOH1803 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 1702 |
| Chain | Residue |
| B | SER1400 |
| B | SER1641 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 1703 |
| Chain | Residue |
| B | HOH1882 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 600 |
| Details | Region: {"description":"Interaction with VCL and F-actin","evidences":[{"source":"PubMed","id":"20610383","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 238 |
| Details | Region: {"description":"Helical bundle R8","evidences":[{"source":"PubMed","id":"23389036","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 144 |
| Details | Region: {"description":"Helical bundle R7B; Interaction with KANK1","evidences":[{"source":"PubMed","id":"27410476","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23389036","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
