6TUX
human XPG-DNA, Complex 2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003697 | molecular_function | single-stranded DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006289 | biological_process | nucleotide-excision repair |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003697 | molecular_function | single-stranded DNA binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006289 | biological_process | nucleotide-excision repair |
| B | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 190 |
| Details | Region: {"description":"I-domain","evidences":[{"source":"PubMed","id":"32522879","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Region: {"description":"DNA-binding; may bind to the undamaged single-strand DNA of the DNA repair bubble","evidences":[{"source":"PubMed","id":"32821917","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TUW","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6TUX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 64 |
| Details | Region: {"description":"DNA-binding; H2TH (helix-2turn-helix) motif which binds double-stranded DNA","evidences":[{"source":"PubMed","id":"32821917","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TUW","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6TUX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Region: {"description":"DNA-binding; may bind double-stranded DNA","evidences":[{"source":"PubMed","id":"32821917","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TUW","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6TUX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P39748","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
