6TSK

Beta-galactosidase in complex with L-ribose

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0004565	molecular_function	beta-galactosidase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0009341	cellular_component	beta-galactosidase complex
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0030246	molecular_function	carbohydrate binding
A	0046872	molecular_function	metal ion binding
B	0003824	molecular_function	catalytic activity
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0004565	molecular_function	beta-galactosidase activity
B	0005975	biological_process	carbohydrate metabolic process
B	0009341	cellular_component	beta-galactosidase complex
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0030246	molecular_function	carbohydrate binding
B	0046872	molecular_function	metal ion binding
C	0003824	molecular_function	catalytic activity
C	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
C	0004565	molecular_function	beta-galactosidase activity
C	0005975	biological_process	carbohydrate metabolic process
C	0009341	cellular_component	beta-galactosidase complex
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0030246	molecular_function	carbohydrate binding
C	0046872	molecular_function	metal ion binding
D	0003824	molecular_function	catalytic activity
D	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
D	0004565	molecular_function	beta-galactosidase activity
D	0005975	biological_process	carbohydrate metabolic process
D	0009341	cellular_component	beta-galactosidase complex
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0030246	molecular_function	carbohydrate binding
D	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00608
Number of Residues	15
Details	GLYCOSYL_HYDROL_F2_2 Glycosyl hydrolases family 2 acid/base catalyst. DRNHPSVIIWSlg.NE

Chain	Residue	Details
A	ASP447-GLU461

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site_id	PS00719
Number of Residues	26
Details	GLYCOSYL_HYDROL_F2_1 Glycosyl hydrolases family 2 signature 1. NaVRCSHYPnhplWYtlcDryGLYVV

Chain	Residue	Details
A	ASN385-VAL410

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_01687

Chain	Residue	Details
A	GLU461
B	GLU461
C	GLU461
D	GLU461

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_01687

Chain	Residue	Details
A	GLU537
B	GLU537
C	GLU537
D	GLU537

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site_id	SWS_FT_FI3
Number of Residues	40
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01687

Chain	Residue	Details
A	ASN102
A	TRP999
B	ASN102
B	ASP201
B	GLU416
B	HIS418
B	GLU461
B	GLU537
B	ASN597
B	PHE601
B	ASN604
A	ASP201
B	TRP999
C	ASN102
C	ASP201
C	GLU416
C	HIS418
C	GLU461
C	GLU537
C	ASN597
C	PHE601
C	ASN604
A	GLU416
C	TRP999
D	ASN102
D	ASP201
D	GLU416
D	HIS418
D	GLU461
D	GLU537
D	ASN597
D	PHE601
D	ASN604
A	HIS418
D	TRP999
A	GLU461
A	GLU537
A	ASN597
A	PHE601
A	ASN604

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site_id	SWS_FT_FI4
Number of Residues	8
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_01687

Chain	Residue	Details
A	HIS357
A	HIS391
B	HIS357
B	HIS391
C	HIS357
C	HIS391
D	HIS357
D	HIS391

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