6TSF

Crystal structure of human L ferritin (HuLf) Fe(III)-loaded for 60 minutes

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0005506	molecular_function	iron ion binding
AAA	0005515	molecular_function	protein binding
AAA	0005576	cellular_component	extracellular region
AAA	0005737	cellular_component	cytoplasm
AAA	0005764	cellular_component	lysosome
AAA	0005776	cellular_component	autophagosome
AAA	0005829	cellular_component	cytosol
AAA	0006826	biological_process	iron ion transport
AAA	0006879	biological_process	intracellular iron ion homeostasis
AAA	0008198	molecular_function	ferrous iron binding
AAA	0008199	molecular_function	ferric iron binding
AAA	0016020	cellular_component	membrane
AAA	0031410	cellular_component	cytoplasmic vesicle
AAA	0035578	cellular_component	azurophil granule lumen
AAA	0042802	molecular_function	identical protein binding
AAA	0044754	cellular_component	autolysosome
AAA	0046872	molecular_function	metal ion binding
AAA	0055072	biological_process	obsolete iron ion homeostasis
AAA	0070062	cellular_component	extracellular exosome
AAA	0070288	cellular_component	ferritin complex

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEthFLdeevklIK

Chain	Residue	Details
AAA	ASP126-LYS146

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EkREgyERLLkmQNqRgGR

Chain	Residue	Details
AAA	GLU61-ARG79

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details