6TS9
Crystal structure of GES-5 carbapenemase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| A | 0046677 | biological_process | response to antibiotic |
| B | 0008800 | molecular_function | beta-lactamase activity |
| B | 0017001 | biological_process | antibiotic catabolic process |
| B | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| B | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 301 |
| Chain | Residue |
| A | SER64 |
| A | SER125 |
| A | LYS229 |
| A | THR230 |
| A | GLY231 |
| A | ARG238 |
| A | HOH511 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue BR A 302 |
| Chain | Residue |
| A | ALA57 |
| A | PRO93 |
| A | ASP94 |
| A | ARG55 |
| A | MET56 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue BR A 303 |
| Chain | Residue |
| A | ARG84 |
| A | LYS88 |
| A | PRO169 |
| A | HOH409 |
| A | HOH419 |
| A | HOH483 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue DMS B 301 |
| Chain | Residue |
| B | SER64 |
| B | SER125 |
| B | THR211 |
| B | LYS229 |
| B | THR230 |
| B | GLY231 |
| B | THR232 |
| B | ARG238 |
| B | HOH458 |
| B | HOH603 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| A | ARG156 |
| A | HOH510 |
| A | HOH609 |
| B | LYS245 |
| B | GLN247 |
| B | GLU248 |
| B | ARG249 |
| B | ASP250 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue BR B 303 |
| Chain | Residue |
| A | LYS222 |
| A | HOH672 |
| B | THR177 |
| B | HOH641 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue BR B 304 |
| Chain | Residue |
| B | ARG55 |
| B | MET56 |
| B | HOH629 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile; acyl-ester intermediate","evidences":[{"source":"PubMed","id":"23148776","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4H8R","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23148776","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4H8R","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
