Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue NW2 A 301 |
| Chain | Residue |
| A | HIS57 |
| A | TRP215 |
| A | GLY216 |
| A | GLY218 |
| A | CYS219 |
| A | HOH478 |
| A | HOH489 |
| A | HOH621 |
| A | LEU146 |
| A | ASP189 |
| A | ALA190 |
| A | CYS191 |
| A | LYS192 |
| A | GLY193 |
| A | SER195 |
| A | THR213 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | HIS178 |
| A | HOH423 |
| A | HOH483 |
| A | HOH557 |
| A | HOH584 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | GLN93 |
| A | TYR101 |
| A | ASP135 |
| A | TRP137 |
| A | LYS179 |
| A | LYS202 |
| A | HOH402 |
| A | HOH404 |
| A | HOH440 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | LYS127 |
| A | GLY128 |
| A | ASP129 |
| A | ARG130 |
| A | HOH413 |
| A | HOH434 |
| A | HOH459 |
| A | HOH506 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 305 |
| Chain | Residue |
| A | PRO161 |
| A | TYR184 |
| A | ARG185 |
| A | HOH465 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 306 |
| Chain | Residue |
| A | TYR172 |
| A | ARG173 |
| A | GLY173 |
| A | HIS174 |
| A | HOH410 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAckGDSGGPLS |
| Chain | Residue | Details |
| A | ASP189-SER198 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LYS170 | |
| Chain | Residue | Details |
| A | ASN73 | |
| Chain | Residue | Details |
| A | ASN113 | |
