6TQT
The crystal structure of the MSP domain of human MOSPD2.
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | LYS317 |
| A | HOH612 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 A 502 |
| Chain | Residue |
| A | HOH671 |
| A | LYS347 |
| A | GLU437 |
| A | HIS438 |
| A | ARG439 |
| A | HOH604 |
| A | HOH646 |
| A | HOH653 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 A 503 |
| Chain | Residue |
| A | LYS324 |
| A | ARG373 |
| A | HIS394 |
| A | GLY395 |
| A | ARG404 |
| A | HOH736 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 118 |
| Details | Domain: {"description":"MSP","evidences":[{"source":"PubMed","id":"29858488","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Region: {"description":"Required for FFAT motif binding and phosphorylated FFAT motif binding","evidences":[{"source":"PubMed","id":"33124732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TQS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6TQU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Required for phosphorylated FFAT motif binding","evidences":[{"source":"PubMed","id":"33124732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TQU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Required for FFAT motif binding","evidences":[{"source":"PubMed","id":"33124732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TQS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
