6TQL
Cryo-EM of elastase-treated human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament
Functional Information from PROSITE/UniProt
| site_id | PS00682 |
| Number of Residues | 41 |
| Details | ZP_1 ZP domain signature. VgtmldggDlsrFaLlMtnCYaTPss..NaTdplkyfIIqdr.C |
| Chain | Residue | Details |
| A | VAL487-CYS527 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | SITE: Cleavage => ECO:0000269|PubMed:18375198 |
| Chain | Residue | Details |
| A | PHE587 | |
| B | PHE587 | |
| C | PHE587 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:22171320, ECO:0000269|PubMed:32616672, ECO:0000269|PubMed:33196145, ECO:0000269|PubMed:35273390, ECO:0007744|PDB:6TQK, ECO:0007744|PDB:6TQL, ECO:0007744|PDB:7PFP |
| Chain | Residue | Details |
| A | ASN322 | |
| B | ASN322 | |
| C | ASN322 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:22171320, ECO:0000269|PubMed:32616672, ECO:0000269|PubMed:32815518, ECO:0000269|PubMed:33196145, ECO:0000269|PubMed:35273390, ECO:0007744|PDB:6TQK, ECO:0007744|PDB:6TQL, ECO:0007744|PDB:6ZS5, ECO:0007744|PDB:6ZYA, ECO:0007744|PDB:7PFP |
| Chain | Residue | Details |
| A | ASN396 | |
| B | ASN396 | |
| C | ASN396 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; alternate => ECO:0000269|PubMed:32616672, ECO:0000269|PubMed:32815518, ECO:0000269|PubMed:33196145, ECO:0007744|PDB:6TQK, ECO:0007744|PDB:6TQL, ECO:0007744|PDB:6ZS5, ECO:0007744|PDB:6ZYA, ECO:0007744|PDB:7PFP |
| Chain | Residue | Details |
| A | ASN513 | |
| B | ASN513 | |
| C | ASN513 |
