6TQG
Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0005829 | cellular_component | cytosol |
| A | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000271 | biological_process | polysaccharide biosynthetic process |
| B | 0005829 | cellular_component | cytosol |
| B | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0000271 | biological_process | polysaccharide biosynthetic process |
| C | 0005829 | cellular_component | cytosol |
| C | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0000271 | biological_process | polysaccharide biosynthetic process |
| D | 0005829 | cellular_component | cytosol |
| D | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009244 | biological_process | lipopolysaccharide core region biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016779 | molecular_function | nucleotidyltransferase activity |
| D | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue NVQ A 301 |
| Chain | Residue |
| A | SER41 |
| A | GLN260 |
| A | HOH419 |
| C | ARG219 |
| A | THR42 |
| A | LEU45 |
| A | TYR113 |
| A | GLY115 |
| A | VAL250 |
| A | ALA251 |
| A | GLU255 |
| A | ARG259 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MES A 302 |
| Chain | Residue |
| A | PHE150 |
| A | GLY154 |
| A | ALA156 |
| A | SER213 |
| A | VAL214 |
| A | ILE216 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 303 |
| Chain | Residue |
| A | HIS116 |
| C | GLY218 |
| C | ARG219 |
| C | GLY220 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 304 |
| Chain | Residue |
| A | GLY218 |
| A | ARG219 |
| A | GLY220 |
| C | HIS116 |
| C | HOH413 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 305 |
| Chain | Residue |
| A | VAL172 |
| A | THR200 |
| A | ASN203 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue NVQ B 301 |
| Chain | Residue |
| B | SER41 |
| B | LEU45 |
| B | TYR113 |
| B | GLY115 |
| B | VAL250 |
| B | ALA251 |
| B | GLU255 |
| B | ARG259 |
| B | GLN260 |
| B | TYR293 |
| B | HOH402 |
| D | ARG219 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MES B 302 |
| Chain | Residue |
| B | PHE150 |
| B | GLY154 |
| B | ALA156 |
| B | VAL214 |
| B | ILE216 |
| B | HOH415 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 303 |
| Chain | Residue |
| B | GLY218 |
| B | ARG219 |
| B | GLY220 |
| D | HIS116 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 304 |
| Chain | Residue |
| B | HIS116 |
| D | GLY220 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 305 |
| Chain | Residue |
| B | THR200 |
| B | ASN203 |
| site_id | AD2 |
| Number of Residues | 12 |
| Details | binding site for residue NVQ C 301 |
| Chain | Residue |
| A | ARG219 |
| C | LEU45 |
| C | TYR113 |
| C | GLY115 |
| C | VAL250 |
| C | ALA251 |
| C | GLU255 |
| C | ARG259 |
| C | GLN260 |
| C | TYR293 |
| C | HOH404 |
| C | HOH413 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue MES C 302 |
| Chain | Residue |
| C | GLY154 |
| C | ALA156 |
| C | VAL214 |
| C | ILE216 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue CL C 303 |
| Chain | Residue |
| C | THR200 |
| C | ASN203 |
| C | HOH409 |
| site_id | AD5 |
| Number of Residues | 13 |
| Details | binding site for residue NVQ D 301 |
| Chain | Residue |
| B | ARG219 |
| D | SER41 |
| D | THR42 |
| D | LEU45 |
| D | TYR113 |
| D | GLY115 |
| D | VAL250 |
| D | ALA251 |
| D | GLU255 |
| D | ARG259 |
| D | GLN260 |
| D | HOH413 |
| D | HOH414 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue MES D 302 |
| Chain | Residue |
| D | GLY154 |
| D | ALA156 |
| D | LEU212 |
| D | VAL214 |
| D | ILE216 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue CL D 303 |
| Chain | Residue |
| D | THR200 |
| D | ASN203 |
