6THM
Linalool Dehydratase Isomerase M125A mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016098 | biological_process | monoterpenoid metabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016836 | molecular_function | hydro-lyase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0043694 | biological_process | monoterpene catabolic process |
| A | 0050486 | molecular_function | intramolecular hydroxytransferase activity |
| B | 0016098 | biological_process | monoterpenoid metabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016836 | molecular_function | hydro-lyase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0043694 | biological_process | monoterpene catabolic process |
| B | 0050486 | molecular_function | intramolecular hydroxytransferase activity |
| C | 0016098 | biological_process | monoterpenoid metabolic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016836 | molecular_function | hydro-lyase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0042597 | cellular_component | periplasmic space |
| C | 0043694 | biological_process | monoterpene catabolic process |
| C | 0050486 | molecular_function | intramolecular hydroxytransferase activity |
| D | 0016098 | biological_process | monoterpenoid metabolic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016836 | molecular_function | hydro-lyase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0042597 | cellular_component | periplasmic space |
| D | 0043694 | biological_process | monoterpene catabolic process |
| D | 0050486 | molecular_function | intramolecular hydroxytransferase activity |
| E | 0016098 | biological_process | monoterpenoid metabolic process |
| E | 0016829 | molecular_function | lyase activity |
| E | 0016836 | molecular_function | hydro-lyase activity |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0042597 | cellular_component | periplasmic space |
| E | 0043694 | biological_process | monoterpene catabolic process |
| E | 0050486 | molecular_function | intramolecular hydroxytransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | TYR66 |
| A | TYR240 |
| A | LEU295 |
| C | ASP39 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | ARG281 |
| A | GLY285 |
| A | THR286 |
| A | ASP287 |
| A | HOH547 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | ASP198 |
| A | TYR199 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| B | PHE209 |
| B | LYS212 |
| B | ASP213 |
| B | LEU214 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | HIS195 |
| B | GLY196 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| B | ASP314 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue MLI B 404 |
| Chain | Residue |
| B | ARG155 |
| B | TYR191 |
| B | HIS195 |
| B | THR197 |
| B | HOH512 |
| C | ARG155 |
| C | TYR191 |
| C | HIS195 |
| C | THR197 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 401 |
| Chain | Residue |
| C | EDO402 |
| C | HOH540 |
| C | HOH545 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 402 |
| Chain | Residue |
| C | TRP189 |
| C | ARG193 |
| C | EDO401 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 401 |
| Chain | Residue |
| D | PHE16 |
| D | ARG305 |
| D | HIS353 |
| D | ALA354 |
| D | GLY355 |
| D | HOH622 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 402 |
| Chain | Residue |
| D | LYS101 |
| D | PRO118 |
| D | ILE119 |
| D | TYR126 |
| D | HOH547 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 403 |
| Chain | Residue |
| D | THR197 |
| D | ASP198 |
| D | TYR199 |
| D | HOH510 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue EDO E 401 |
| Chain | Residue |
| E | TYR240 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO E 402 |
| Chain | Residue |
| E | ARG8 |
| E | LEU9 |
| E | HOH560 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO E 403 |
| Chain | Residue |
| D | TYR240 |
| E | ASP39 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO E 404 |
| Chain | Residue |
| E | ALA2 |
| E | HOH620 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue MLI E 405 |
| Chain | Residue |
| D | ARG155 |
| D | TYR191 |
| D | HIS195 |
| E | ARG155 |
| E | TYR191 |
| E | HIS195 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000305|DOI:10.1021/acscatal.0c02958 |
| Chain | Residue | Details |
| A | MET35 | |
| B | MET35 | |
| C | MET35 | |
| D | MET35 | |
| E | MET35 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27062179, ECO:0007744|PDB:5HSS |
| Chain | Residue | Details |
| A | ALA167 | |
| B | ALA167 | |
| C | ALA167 | |
| D | ALA167 | |
| E | ALA167 |
