6TDB
Neuropilin2-b1 domain in a complex with the C-terminal VEGFB167 peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001525 | biological_process | angiogenesis |
| A | 0005021 | molecular_function | vascular endothelial growth factor receptor activity |
| A | 0007411 | biological_process | axon guidance |
| A | 0017154 | molecular_function | semaphorin receptor activity |
| A | 0038084 | biological_process | vascular endothelial growth factor signaling pathway |
| B | 0001525 | biological_process | angiogenesis |
| B | 0005021 | molecular_function | vascular endothelial growth factor receptor activity |
| B | 0007411 | biological_process | axon guidance |
| B | 0017154 | molecular_function | semaphorin receptor activity |
| B | 0038084 | biological_process | vascular endothelial growth factor signaling pathway |
| C | 0001525 | biological_process | angiogenesis |
| C | 0005021 | molecular_function | vascular endothelial growth factor receptor activity |
| C | 0007411 | biological_process | axon guidance |
| C | 0017154 | molecular_function | semaphorin receptor activity |
| C | 0038084 | biological_process | vascular endothelial growth factor signaling pathway |
| D | 0001525 | biological_process | angiogenesis |
| D | 0005021 | molecular_function | vascular endothelial growth factor receptor activity |
| D | 0007411 | biological_process | axon guidance |
| D | 0017154 | molecular_function | semaphorin receptor activity |
| D | 0038084 | biological_process | vascular endothelial growth factor signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | LYS382 |
| A | GLN385 |
| A | ASN388 |
| A | ASP389 |
| A | ASN396 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| B | ARG421 |
| B | GLY313 |
| B | ASN316 |
| B | ALA347 |
| B | ILE348 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 501 |
| Chain | Residue |
| C | ASN278 |
| C | THR340 |
| C | ALA341 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide ACE F 301 and ARG F 228 |
| Chain | Residue |
| B | ASP301 |
| B | TRP304 |
| B | THR319 |
| B | SER349 |
| B | GLU351 |
| B | TYR356 |
| B | ILE418 |
| F | LYS229 |
Functional Information from PROSITE/UniProt
| site_id | PS01285 |
| Number of Residues | 30 |
| Details | FA58C_1 Coagulation factors 5/8 type C domain (FA58C) signature 1. GWtpnldsnke......YLqVDlrfltmLtaIaTQG |
| Chain | Residue | Details |
| A | GLY317-GLY346 |
| site_id | PS01286 |
| Number of Residues | 17 |
| Details | FA58C_2 Coagulation factors 5/8 type C domain (FA58C) signature 2. Pqtwhsgia..LRlELfGC |
| Chain | Residue | Details |
| A | PRO411-CYS427 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 600 |
| Details | Domain: {"description":"F5/8 type C 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00081","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 76 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 48 |
| Details | Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
