6TBI
Structure of a beta galactosidase with inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004565 | molecular_function | beta-galactosidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0009341 | cellular_component | beta-galactosidase complex |
| B | 0004565 | molecular_function | beta-galactosidase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0009341 | cellular_component | beta-galactosidase complex |
| C | 0004565 | molecular_function | beta-galactosidase activity |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0009341 | cellular_component | beta-galactosidase complex |
| D | 0004565 | molecular_function | beta-galactosidase activity |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0009341 | cellular_component | beta-galactosidase complex |
| E | 0004565 | molecular_function | beta-galactosidase activity |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0009341 | cellular_component | beta-galactosidase complex |
| F | 0004565 | molecular_function | beta-galactosidase activity |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0009341 | cellular_component | beta-galactosidase complex |
| G | 0004565 | molecular_function | beta-galactosidase activity |
| G | 0005975 | biological_process | carbohydrate metabolic process |
| G | 0009341 | cellular_component | beta-galactosidase complex |
| H | 0004565 | molecular_function | beta-galactosidase activity |
| H | 0005975 | biological_process | carbohydrate metabolic process |
| H | 0009341 | cellular_component | beta-galactosidase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 601 |
| Chain | Residue |
| A | ASP464 |
| A | GLY466 |
| A | SER518 |
| A | GLN519 |
| A | NA604 |
| A | HOH883 |
| A | HOH1090 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 602 |
| Chain | Residue |
| A | HOH970 |
| A | MET410 |
| A | ARG411 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 603 |
| Chain | Residue |
| A | GLU533 |
| A | GLU544 |
| A | HOH744 |
| A | HOH803 |
| A | HOH884 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 604 |
| Chain | Residue |
| A | SER518 |
| A | GLN519 |
| A | NA601 |
| A | HOH813 |
| A | HOH883 |
| A | HOH1088 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 605 |
| Chain | Residue |
| A | HIS49 |
| A | GLY367 |
| A | SER417 |
| A | HOH979 |
| A | HOH1012 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue N8V A 606 |
| Chain | Residue |
| A | ASN67 |
| A | LYS134 |
| A | ASN135 |
| A | ASN204 |
| A | GLU205 |
| A | TYR324 |
| A | GLU349 |
| A | PHE374 |
| A | ASN383 |
| A | LEU386 |
| A | HOH768 |
| A | HOH965 |
| C | ASP550 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue NA B 601 |
| Chain | Residue |
| B | ASP464 |
| B | GLY466 |
| B | SER518 |
| B | NA606 |
| B | HOH1012 |
| B | HOH1033 |
| B | HOH1168 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 602 |
| Chain | Residue |
| B | GLY523 |
| B | HOH732 |
| B | HOH749 |
| H | ASP161 |
| H | THR162 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 603 |
| Chain | Residue |
| B | ARG191 |
| B | HOH701 |
| G | PHE288 |
| G | HOH1398 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 604 |
| Chain | Residue |
| B | GLU533 |
| B | GLU544 |
| B | HOH775 |
| B | HOH802 |
| B | HOH933 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 605 |
| Chain | Residue |
| B | THR488 |
| B | HOH910 |
| B | HOH1028 |
| B | HOH1062 |
| B | HOH1151 |
| B | HOH1157 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 606 |
| Chain | Residue |
| B | SER518 |
| B | NA601 |
| B | HOH949 |
| B | HOH1012 |
| B | HOH1033 |
| B | HOH1160 |
| site_id | AD4 |
| Number of Residues | 12 |
| Details | binding site for residue N8V B 607 |
| Chain | Residue |
| A | ASP550 |
| B | ASN67 |
| B | LYS134 |
| B | ASN135 |
| B | ASN204 |
| B | GLU205 |
| B | TYR324 |
| B | GLU349 |
| B | PHE374 |
| B | ASN383 |
| B | HOH746 |
| B | HOH1064 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 601 |
| Chain | Residue |
| C | SER518 |
| C | NA602 |
| C | HOH910 |
| C | HOH967 |
| C | HOH1088 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue NA C 602 |
| Chain | Residue |
| C | ASP464 |
| C | GLY466 |
| C | SER518 |
| C | NA601 |
| C | HOH910 |
| C | HOH1088 |
| C | HOH1157 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue ACT C 603 |
| Chain | Residue |
| C | HOH1023 |
| C | HOH1130 |
| C | ARG411 |
| C | HOH715 |
| C | HOH725 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 604 |
| Chain | Residue |
| C | GLU533 |
| C | GLU544 |
| C | HOH754 |
| C | HOH761 |
| C | HOH987 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 605 |
| Chain | Residue |
| C | HIS49 |
| C | GLY367 |
| C | SER417 |
| C | HOH939 |
| C | HOH1094 |
| site_id | AE1 |
| Number of Residues | 12 |
| Details | binding site for residue N8V C 606 |
| Chain | Residue |
| C | ASN67 |
| C | LYS134 |
| C | ASN135 |
| C | ASN204 |
| C | GLU205 |
| C | TYR324 |
| C | GLU349 |
| C | PHE374 |
| C | ASN383 |
| C | HOH815 |
| C | HOH1059 |
| H | ASP550 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue NA D 601 |
| Chain | Residue |
| D | SER571 |
| D | HOH1102 |
| D | HOH1113 |
| D | HOH1210 |
| D | HOH1263 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue NA D 602 |
| Chain | Residue |
| D | SER518 |
| D | NA603 |
| D | HOH809 |
| D | HOH829 |
| D | HOH920 |
| D | HOH1206 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue NA D 603 |
| Chain | Residue |
| D | ASP464 |
| D | GLY466 |
| D | SER518 |
| D | NA602 |
| D | HOH809 |
| D | HOH829 |
| G | HOH1161 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue ACT D 604 |
| Chain | Residue |
| D | ARG411 |
| D | HOH785 |
| D | HOH1037 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue ACT D 605 |
| Chain | Residue |
| C | GLY291 |
| C | LEU292 |
| C | HOH1278 |
| D | ARG119 |
| D | HOH763 |
| D | HOH956 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue NA D 606 |
| Chain | Residue |
| D | GLU533 |
| D | GLU544 |
| D | HOH918 |
| D | HOH938 |
| D | HOH1236 |
| D | HOH1313 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue NA D 607 |
| Chain | Residue |
| D | HIS49 |
| D | GLY367 |
| D | SER417 |
| D | HOH1072 |
| D | HOH1140 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue NA D 608 |
| Chain | Residue |
| D | LEU364 |
| D | GLY367 |
| D | GLY368 |
| D | TRP413 |
| D | SER417 |
| site_id | AF1 |
| Number of Residues | 14 |
| Details | binding site for residue N8V D 609 |
| Chain | Residue |
| D | ASN67 |
| D | LYS134 |
| D | ASN135 |
| D | ASN204 |
| D | GLU205 |
| D | TYR324 |
| D | GLU349 |
| D | PHE374 |
| D | ASN383 |
| D | HOH769 |
| D | HOH1017 |
| E | PHE479 |
| E | TRP480 |
| E | ASP550 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue NA E 601 |
| Chain | Residue |
| E | SER571 |
| E | HOH969 |
| E | HOH1094 |
| E | HOH1278 |
| F | HOH789 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue NA E 602 |
| Chain | Residue |
| E | ASP464 |
| E | GLY466 |
| E | SER518 |
| E | NA603 |
| E | HOH814 |
| E | HOH892 |
| F | HOH1061 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue NA E 603 |
| Chain | Residue |
| E | SER518 |
| E | NA602 |
| E | HOH813 |
| E | HOH814 |
| E | HOH892 |
| E | HOH1223 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT E 604 |
| Chain | Residue |
| E | ASP161 |
| E | THR162 |
| E | HOH722 |
| E | HOH755 |
| G | GLY523 |
| G | HOH733 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue ACT E 605 |
| Chain | Residue |
| E | ARG191 |
| E | HOH727 |
| H | PHE288 |
| site_id | AF7 |
| Number of Residues | 8 |
| Details | binding site for residue ACT E 606 |
| Chain | Residue |
| E | GLY291 |
| E | LEU292 |
| E | HOH709 |
| E | HOH1015 |
| H | ARG119 |
| H | HOH1034 |
| H | HOH1116 |
| H | HOH1214 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue ACT E 607 |
| Chain | Residue |
| E | ARG411 |
| E | HOH737 |
| E | HOH862 |
| E | HOH1042 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue NA E 608 |
| Chain | Residue |
| E | HIS49 |
| E | GLY367 |
| E | SER417 |
| E | HOH1151 |
| site_id | AG1 |
| Number of Residues | 3 |
| Details | binding site for residue NA E 609 |
| Chain | Residue |
| E | GLN98 |
| E | ASP107 |
| E | HOH1332 |
| site_id | AG2 |
| Number of Residues | 7 |
| Details | binding site for residue NA E 610 |
| Chain | Residue |
| E | GLU533 |
| E | GLU544 |
| E | HOH749 |
| E | HOH771 |
| E | HOH992 |
| E | HOH1218 |
| E | HOH1312 |
| site_id | AG3 |
| Number of Residues | 12 |
| Details | binding site for residue N8V E 611 |
| Chain | Residue |
| E | ASN67 |
| E | LYS134 |
| E | ASN135 |
| E | ASN204 |
| E | GLU205 |
| E | TYR324 |
| E | GLU349 |
| E | PHE374 |
| E | ASN383 |
| E | HOH780 |
| E | HOH1011 |
| G | ASP550 |
| site_id | AG4 |
| Number of Residues | 5 |
| Details | binding site for residue NA F 601 |
| Chain | Residue |
| F | SER571 |
| F | HOH1016 |
| F | HOH1031 |
| F | HOH1186 |
| F | HOH1213 |
| site_id | AG5 |
| Number of Residues | 6 |
| Details | binding site for residue NA F 602 |
| Chain | Residue |
| F | SER518 |
| F | NA603 |
| F | HOH860 |
| F | HOH891 |
| F | HOH902 |
| F | HOH1184 |
| site_id | AG6 |
| Number of Residues | 7 |
| Details | binding site for residue NA F 603 |
| Chain | Residue |
| E | HOH1142 |
| F | ASP464 |
| F | GLY466 |
| F | SER518 |
| F | NA602 |
| F | HOH860 |
| F | HOH891 |
| site_id | AG7 |
| Number of Residues | 3 |
| Details | binding site for residue ACT F 604 |
| Chain | Residue |
| F | MET410 |
| F | ARG411 |
| F | HOH1065 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for residue ACT F 605 |
| Chain | Residue |
| F | TYR328 |
| F | HOH716 |
| F | HOH1001 |
| F | HOH1126 |
| site_id | AG9 |
| Number of Residues | 5 |
| Details | binding site for residue NA F 606 |
| Chain | Residue |
| F | HIS49 |
| F | GLY367 |
| F | SER417 |
| F | HOH995 |
| F | HOH1123 |
| site_id | AH1 |
| Number of Residues | 13 |
| Details | binding site for residue N8V F 607 |
| Chain | Residue |
| D | PHE479 |
| D | ASP550 |
| F | ASN67 |
| F | LYS134 |
| F | ASN135 |
| F | ASN204 |
| F | GLU205 |
| F | TYR324 |
| F | GLU349 |
| F | PHE374 |
| F | ASN383 |
| F | HOH778 |
| F | HOH1059 |
| site_id | AH2 |
| Number of Residues | 5 |
| Details | binding site for residue NA G 601 |
| Chain | Residue |
| D | HOH1409 |
| G | SER571 |
| G | HOH1130 |
| G | HOH1215 |
| G | HOH1235 |
| site_id | AH3 |
| Number of Residues | 7 |
| Details | binding site for residue NA G 602 |
| Chain | Residue |
| D | HOH1155 |
| G | ASP464 |
| G | GLY466 |
| G | SER518 |
| G | NA609 |
| G | HOH947 |
| G | HOH979 |
| site_id | AH4 |
| Number of Residues | 6 |
| Details | binding site for residue ACT G 603 |
| Chain | Residue |
| F | GLY523 |
| G | ASP161 |
| G | THR162 |
| G | HOH712 |
| G | HOH779 |
| G | HOH880 |
| site_id | AH5 |
| Number of Residues | 4 |
| Details | binding site for residue ACT G 604 |
| Chain | Residue |
| G | THR432 |
| G | HIS451 |
| G | ARG455 |
| G | HOH998 |
| site_id | AH6 |
| Number of Residues | 4 |
| Details | binding site for residue ACT G 605 |
| Chain | Residue |
| G | MET410 |
| G | ARG411 |
| G | HOH873 |
| G | HOH1077 |
| site_id | AH7 |
| Number of Residues | 5 |
| Details | binding site for residue ACT G 606 |
| Chain | Residue |
| B | PHE288 |
| G | ARG191 |
| G | HOH847 |
| G | HOH883 |
| G | HOH1194 |
| site_id | AH8 |
| Number of Residues | 4 |
| Details | binding site for residue NA G 607 |
| Chain | Residue |
| G | HIS49 |
| G | GLY367 |
| G | SER417 |
| G | HOH1195 |
| site_id | AH9 |
| Number of Residues | 6 |
| Details | binding site for residue NA G 608 |
| Chain | Residue |
| G | GLU533 |
| G | GLU544 |
| G | HOH868 |
| G | HOH940 |
| G | HOH983 |
| G | HOH1339 |
| site_id | AI1 |
| Number of Residues | 6 |
| Details | binding site for residue NA G 609 |
| Chain | Residue |
| G | SER518 |
| G | NA602 |
| G | HOH888 |
| G | HOH947 |
| G | HOH979 |
| G | HOH1201 |
| site_id | AI2 |
| Number of Residues | 12 |
| Details | binding site for residue N8V G 610 |
| Chain | Residue |
| F | ASP550 |
| G | ASN67 |
| G | LYS134 |
| G | ASN135 |
| G | ASN204 |
| G | GLU205 |
| G | TYR324 |
| G | GLU349 |
| G | PHE374 |
| G | ASN383 |
| G | HOH830 |
| G | HOH1030 |
| site_id | AI3 |
| Number of Residues | 7 |
| Details | binding site for residue NA H 601 |
| Chain | Residue |
| H | ASP464 |
| H | GLY466 |
| H | SER518 |
| H | GLN519 |
| H | NA606 |
| H | HOH853 |
| H | HOH1146 |
| site_id | AI4 |
| Number of Residues | 2 |
| Details | binding site for residue ACT H 602 |
| Chain | Residue |
| H | ARG411 |
| H | HOH1046 |
| site_id | AI5 |
| Number of Residues | 5 |
| Details | binding site for residue NA H 603 |
| Chain | Residue |
| H | GLU533 |
| H | GLU544 |
| H | HOH756 |
| H | HOH778 |
| H | HOH943 |
| site_id | AI6 |
| Number of Residues | 5 |
| Details | binding site for residue NA H 604 |
| Chain | Residue |
| H | HIS49 |
| H | GLY367 |
| H | SER417 |
| H | HOH761 |
| H | HOH1084 |
| site_id | AI7 |
| Number of Residues | 6 |
| Details | binding site for residue NA H 605 |
| Chain | Residue |
| H | THR488 |
| H | HOH828 |
| H | HOH947 |
| H | HOH997 |
| H | HOH1129 |
| H | HOH1133 |
| site_id | AI8 |
| Number of Residues | 6 |
| Details | binding site for residue NA H 606 |
| Chain | Residue |
| H | SER518 |
| H | GLN519 |
| H | NA601 |
| H | HOH812 |
| H | HOH853 |
| H | HOH1153 |
| site_id | AI9 |
| Number of Residues | 12 |
| Details | binding site for residue N8V H 607 |
| Chain | Residue |
| B | ASP550 |
| H | ASN67 |
| H | LYS134 |
| H | ASN135 |
| H | ASN204 |
| H | GLU205 |
| H | TYR324 |
| H | GLU349 |
| H | PHE374 |
| H | ASN383 |
| H | HOH782 |
| H | HOH945 |
