6TBG
Structure of a beta galactosidase with inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004565 | molecular_function | beta-galactosidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0009341 | cellular_component | beta-galactosidase complex |
| B | 0004565 | molecular_function | beta-galactosidase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0009341 | cellular_component | beta-galactosidase complex |
| C | 0004565 | molecular_function | beta-galactosidase activity |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0009341 | cellular_component | beta-galactosidase complex |
| D | 0004565 | molecular_function | beta-galactosidase activity |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0009341 | cellular_component | beta-galactosidase complex |
| E | 0004565 | molecular_function | beta-galactosidase activity |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0009341 | cellular_component | beta-galactosidase complex |
| F | 0004565 | molecular_function | beta-galactosidase activity |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0009341 | cellular_component | beta-galactosidase complex |
| G | 0004565 | molecular_function | beta-galactosidase activity |
| G | 0005975 | biological_process | carbohydrate metabolic process |
| G | 0009341 | cellular_component | beta-galactosidase complex |
| H | 0004565 | molecular_function | beta-galactosidase activity |
| H | 0005975 | biological_process | carbohydrate metabolic process |
| H | 0009341 | cellular_component | beta-galactosidase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 601 |
| Chain | Residue |
| A | ASP464 |
| A | GLY466 |
| A | SER518 |
| A | GLN519 |
| A | NA606 |
| A | HOH798 |
| A | HOH1071 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue N0N A 602 |
| Chain | Residue |
| A | ASN135 |
| A | ASN204 |
| A | GLU205 |
| A | ASP322 |
| A | TYR324 |
| A | PHE325 |
| A | GLU349 |
| A | PHE374 |
| A | ASN383 |
| A | LEU386 |
| A | HOH776 |
| A | HOH1017 |
| C | ASP550 |
| A | ASN67 |
| A | LYS134 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 603 |
| Chain | Residue |
| A | ARG411 |
| A | HOH923 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 604 |
| Chain | Residue |
| A | GLU533 |
| A | GLU544 |
| A | HOH736 |
| A | HOH800 |
| A | HOH906 |
| A | HOH1122 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 605 |
| Chain | Residue |
| A | HIS49 |
| A | GLY367 |
| A | SER417 |
| A | HOH1020 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 606 |
| Chain | Residue |
| A | SER518 |
| A | GLN519 |
| A | NA601 |
| A | HOH798 |
| A | HOH944 |
| A | HOH1062 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 601 |
| Chain | Residue |
| B | ASP464 |
| B | GLY466 |
| B | SER518 |
| B | HOH1032 |
| B | HOH1111 |
| B | HOH1132 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | binding site for residue N0N B 602 |
| Chain | Residue |
| A | ASP550 |
| B | ASN67 |
| B | LYS134 |
| B | ASN135 |
| B | ASN204 |
| B | GLU205 |
| B | ASP322 |
| B | TYR324 |
| B | GLU349 |
| B | PHE374 |
| B | ASN383 |
| B | HOH758 |
| B | HOH810 |
| B | HOH1089 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 603 |
| Chain | Residue |
| B | GLY523 |
| B | HOH731 |
| B | HOH763 |
| B | HOH903 |
| H | ASP161 |
| H | THR162 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue ACT B 604 |
| Chain | Residue |
| B | THR432 |
| B | ARG455 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 605 |
| Chain | Residue |
| B | THR488 |
| B | HOH940 |
| B | HOH960 |
| B | HOH1028 |
| B | HOH1112 |
| B | HOH1146 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue NA C 601 |
| Chain | Residue |
| C | SER518 |
| C | NA602 |
| C | HOH960 |
| C | HOH996 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 602 |
| Chain | Residue |
| C | ASP464 |
| C | GLY466 |
| C | SER518 |
| C | NA601 |
| C | HOH996 |
| site_id | AD5 |
| Number of Residues | 18 |
| Details | binding site for residue N0N C 603 |
| Chain | Residue |
| C | HOH1044 |
| H | ASP550 |
| C | ASN67 |
| C | LYS134 |
| C | ASN135 |
| C | ASN204 |
| C | GLU205 |
| C | TYR209 |
| C | LEU284 |
| C | TYR296 |
| C | ASP322 |
| C | TYR324 |
| C | GLU349 |
| C | PHE374 |
| C | ASN383 |
| C | HOH765 |
| C | HOH780 |
| C | HOH940 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue ACT C 604 |
| Chain | Residue |
| C | ARG411 |
| C | HOH981 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue NA C 605 |
| Chain | Residue |
| C | GLU533 |
| C | GLU544 |
| C | HOH742 |
| C | HOH866 |
| C | HOH900 |
| C | HOH1177 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue NA C 606 |
| Chain | Residue |
| C | HIS49 |
| C | GLY367 |
| C | SER417 |
| C | HOH1069 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue NA D 601 |
| Chain | Residue |
| D | SER571 |
| D | HOH1043 |
| D | HOH1093 |
| D | HOH1143 |
| D | HOH1204 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue NA D 602 |
| Chain | Residue |
| D | SER518 |
| D | NA603 |
| D | HOH809 |
| D | HOH814 |
| D | HOH848 |
| G | HOH1304 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue NA D 603 |
| Chain | Residue |
| D | ASP464 |
| D | GLY466 |
| D | SER518 |
| D | NA602 |
| D | HOH809 |
| D | HOH814 |
| D | HOH1161 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue ACT D 604 |
| Chain | Residue |
| D | ARG411 |
| D | HOH725 |
| D | HOH745 |
| D | HOH1034 |
| site_id | AE4 |
| Number of Residues | 19 |
| Details | binding site for residue N0N D 605 |
| Chain | Residue |
| D | ASN67 |
| D | LYS134 |
| D | ASN135 |
| D | ASN204 |
| D | GLU205 |
| D | ASP322 |
| D | TYR324 |
| D | PHE325 |
| D | GLU349 |
| D | PHE374 |
| D | ASN383 |
| D | LEU386 |
| D | HOH744 |
| D | HOH757 |
| D | HOH791 |
| D | HOH997 |
| D | HOH1076 |
| E | TRP480 |
| E | ASP550 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue ACT D 606 |
| Chain | Residue |
| D | TYR328 |
| D | HOH797 |
| D | HOH821 |
| D | HOH1097 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue ACT D 607 |
| Chain | Residue |
| C | GLY291 |
| C | LEU292 |
| C | HOH1207 |
| D | ARG119 |
| D | HOH740 |
| D | HOH931 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue ACT D 608 |
| Chain | Residue |
| D | THR162 |
| D | HOH746 |
| E | GLY523 |
| E | HOH763 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue NA D 609 |
| Chain | Residue |
| D | GLU533 |
| D | GLU544 |
| D | HOH895 |
| D | HOH901 |
| D | HOH1216 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue NA D 610 |
| Chain | Residue |
| D | HIS49 |
| D | GLY367 |
| D | SER417 |
| D | HOH1101 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue NA E 601 |
| Chain | Residue |
| E | SER571 |
| E | HOH975 |
| E | HOH1083 |
| E | HOH1196 |
| F | HOH840 |
| site_id | AF2 |
| Number of Residues | 7 |
| Details | binding site for residue NA E 602 |
| Chain | Residue |
| E | ASP464 |
| E | GLY466 |
| E | SER518 |
| E | NA603 |
| E | HOH727 |
| E | HOH848 |
| E | HOH1174 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue NA E 603 |
| Chain | Residue |
| E | SER518 |
| E | NA602 |
| E | HOH727 |
| E | HOH848 |
| E | HOH873 |
| E | HOH1157 |
| site_id | AF4 |
| Number of Residues | 17 |
| Details | binding site for residue N0N E 604 |
| Chain | Residue |
| E | ASN67 |
| E | LYS134 |
| E | ASN135 |
| E | ASN204 |
| E | GLU205 |
| E | ASP322 |
| E | TYR324 |
| E | PHE325 |
| E | GLU349 |
| E | PHE374 |
| E | ASN383 |
| E | LEU386 |
| E | HOH707 |
| E | HOH752 |
| E | HOH1070 |
| G | TRP480 |
| G | ASP550 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT E 605 |
| Chain | Residue |
| E | ASP161 |
| E | THR162 |
| E | HOH717 |
| E | HOH740 |
| G | GLY523 |
| G | HOH735 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue ACT E 606 |
| Chain | Residue |
| E | ARG191 |
| E | HOH711 |
| E | HOH843 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue ACT E 607 |
| Chain | Residue |
| E | THR432 |
| E | ASN440 |
| E | HIS451 |
| E | ARG455 |
| E | HOH704 |
| E | HOH713 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue NA E 608 |
| Chain | Residue |
| E | HIS49 |
| E | GLY367 |
| E | SER417 |
| E | HOH1096 |
| site_id | AF9 |
| Number of Residues | 6 |
| Details | binding site for residue NA E 609 |
| Chain | Residue |
| E | GLU533 |
| E | GLU544 |
| E | HOH784 |
| E | HOH806 |
| E | HOH913 |
| E | HOH1220 |
| site_id | AG1 |
| Number of Residues | 4 |
| Details | binding site for residue NA F 601 |
| Chain | Residue |
| F | SER571 |
| F | HOH1013 |
| F | HOH1096 |
| F | HOH1108 |
| site_id | AG2 |
| Number of Residues | 6 |
| Details | binding site for residue NA F 602 |
| Chain | Residue |
| F | SER518 |
| F | NA603 |
| F | HOH745 |
| F | HOH847 |
| F | HOH885 |
| F | HOH1092 |
| site_id | AG3 |
| Number of Residues | 7 |
| Details | binding site for residue NA F 603 |
| Chain | Residue |
| E | HOH1112 |
| F | ASP464 |
| F | GLY466 |
| F | SER518 |
| F | NA602 |
| F | HOH745 |
| F | HOH885 |
| site_id | AG4 |
| Number of Residues | 18 |
| Details | binding site for residue N0N F 604 |
| Chain | Residue |
| D | TRP480 |
| D | ASP550 |
| F | ASN67 |
| F | LYS134 |
| F | ASN135 |
| F | ASN204 |
| F | GLU205 |
| F | ASP322 |
| F | TYR324 |
| F | PHE325 |
| F | GLU349 |
| F | PHE374 |
| F | ASN383 |
| F | LEU386 |
| F | HOH748 |
| F | HOH753 |
| F | HOH1021 |
| F | HOH1048 |
| site_id | AG5 |
| Number of Residues | 3 |
| Details | binding site for residue ACT F 605 |
| Chain | Residue |
| F | ARG411 |
| F | HOH770 |
| F | HOH900 |
| site_id | AG6 |
| Number of Residues | 2 |
| Details | binding site for residue ACT F 606 |
| Chain | Residue |
| F | TYR328 |
| F | HOH875 |
| site_id | AG7 |
| Number of Residues | 4 |
| Details | binding site for residue NA F 607 |
| Chain | Residue |
| F | HIS49 |
| F | GLY367 |
| F | SER417 |
| F | HOH1079 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for residue NA G 601 |
| Chain | Residue |
| G | SER571 |
| G | HOH1116 |
| G | HOH1173 |
| G | HOH1189 |
| site_id | AG9 |
| Number of Residues | 7 |
| Details | binding site for residue NA G 602 |
| Chain | Residue |
| D | HOH1082 |
| G | ASP464 |
| G | GLY466 |
| G | SER518 |
| G | NA609 |
| G | HOH811 |
| G | HOH836 |
| site_id | AH1 |
| Number of Residues | 19 |
| Details | binding site for residue N0N G 603 |
| Chain | Residue |
| F | PHE479 |
| F | TRP480 |
| F | ASP550 |
| G | ASN67 |
| G | LYS134 |
| G | ASN135 |
| G | ASN204 |
| G | GLU205 |
| G | ASP322 |
| G | TYR324 |
| G | PHE325 |
| G | GLU349 |
| G | PHE374 |
| G | ASN383 |
| G | LEU386 |
| G | HOH704 |
| G | HOH809 |
| G | HOH1077 |
| G | HOH1106 |
| site_id | AH2 |
| Number of Residues | 5 |
| Details | binding site for residue ACT G 604 |
| Chain | Residue |
| F | GLY523 |
| F | HOH712 |
| G | THR162 |
| G | HOH739 |
| G | HOH740 |
| site_id | AH3 |
| Number of Residues | 4 |
| Details | binding site for residue ACT G 605 |
| Chain | Residue |
| G | THR432 |
| G | HIS451 |
| G | ARG455 |
| G | HOH708 |
| site_id | AH4 |
| Number of Residues | 3 |
| Details | binding site for residue ACT G 606 |
| Chain | Residue |
| G | ARG411 |
| G | HOH754 |
| G | HOH1014 |
| site_id | AH5 |
| Number of Residues | 7 |
| Details | binding site for residue ACT G 607 |
| Chain | Residue |
| B | LYS329 |
| G | LYS190 |
| G | ARG191 |
| G | HOH701 |
| G | HOH728 |
| G | HOH986 |
| G | HOH1043 |
| site_id | AH6 |
| Number of Residues | 6 |
| Details | binding site for residue NA G 608 |
| Chain | Residue |
| G | GLU533 |
| G | GLU544 |
| G | HOH912 |
| G | HOH963 |
| G | HOH972 |
| G | HOH1249 |
| site_id | AH7 |
| Number of Residues | 6 |
| Details | binding site for residue NA G 609 |
| Chain | Residue |
| G | SER518 |
| G | NA602 |
| G | HOH811 |
| G | HOH836 |
| G | HOH838 |
| G | HOH1164 |
| site_id | AH8 |
| Number of Residues | 5 |
| Details | binding site for residue NA H 601 |
| Chain | Residue |
| H | ASP464 |
| H | GLY466 |
| H | SER518 |
| H | GLN519 |
| H | HOH876 |
| site_id | AH9 |
| Number of Residues | 15 |
| Details | binding site for residue N0N H 602 |
| Chain | Residue |
| B | ASP550 |
| H | ASN67 |
| H | LYS134 |
| H | ASN135 |
| H | ASN204 |
| H | GLU205 |
| H | ASP322 |
| H | TYR324 |
| H | PHE325 |
| H | GLU349 |
| H | PHE374 |
| H | ASN383 |
| H | LEU386 |
| H | HOH795 |
| H | HOH1033 |
| site_id | AI1 |
| Number of Residues | 3 |
| Details | binding site for residue ACT H 603 |
| Chain | Residue |
| H | ARG411 |
| H | HOH772 |
| H | HOH1016 |
| site_id | AI2 |
| Number of Residues | 6 |
| Details | binding site for residue NA H 604 |
| Chain | Residue |
| H | GLU533 |
| H | GLU544 |
| H | HOH742 |
| H | HOH778 |
| H | HOH826 |
| H | HOH1141 |
