6TAX

Mouse RNF213 wild type protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004842	molecular_function	ubiquitin-protein transferase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue ATP A 5201

Chain	Residue
A	GLY1957
A	GLU2119
A	TRP2173
A	ARG2177
A	LYS2460
A	SER2535
A	MG5202
A	VAL1958
A	GLY1959
A	LYS1960
A	SER1961
A	LEU1962
A	GLU2060
A	ALA2114
A	ASP2116

---

site_id	AC2
Number of Residues	3
Details	binding site for residue MG A 5202

Chain	Residue
A	SER1961
A	GLU2060
A	ATP5201

---

site_id	AC3
Number of Residues	5
Details	binding site for residue ZN A 5203

Chain	Residue
A	LEU3960
A	CYS3962
A	HIS3964
A	CYS3982
A	CYS3985

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 5204

Chain	Residue
A	CYS3947
A	CYS3950
A	CYS3967
A	CYS3970

---

Functional Information from PROSITE/UniProt

site_id	PS00518
Number of Residues	10
Details	ZF_RING_1 Zinc finger RING-type signature. CdHvYClrCI

Chain	Residue	Details
A	CYS3962-ILE3971

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	39
Details	ZN_FING: RING-type => ECO:0000255|PROSITE-ProRule:PRU00175

Chain	Residue	Details
A	CYS3947-LEU3986

---

site_id	SWS_FT_FI2
Number of Residues	72
Details	ZN_FING: RZ-type => ECO:0000255|PROSITE-ProRule:PRU01325

Chain	Residue	Details
A	MET4429-THR4501

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	ACT_SITE: Nucleophile; for E3 ubiquitin-lipopolysaccharide ligase activity => ECO:0000255|PROSITE-ProRule:PRU01325

Chain	Residue	Details
A	CYS4462

---

site_id	SWS_FT_FI4
Number of Residues	11
Details	BINDING: BINDING => ECO:0000269|PubMed:32573437, ECO:0007744|PDB:6TAX, ECO:0007744|PDB:6TAY

Chain	Residue	Details
A	GLY1957
A	CYS3982
A	CYS3985
A	GLU2060
A	ASP2116
A	CYS3947
A	CYS3950
A	CYS3962
A	HIS3964
A	CYS3967
A	CYS3970

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:32573437, ECO:0007744|PDB:6TAY

Chain	Residue	Details
A	ALA2114
A	LYS2460

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:32573437, ECO:0007744|PDB:6TAX

Chain	Residue	Details
A	ARG2177
A	SER2535

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01325

Chain	Residue	Details
A	CYS4451
A	HIS4455
A	CYS4471
A	CYS4474

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q63HN8

Chain	Residue	Details
A	SER2234

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:Q63HN8

Chain	Residue	Details
A	LYS1128

---