6TAK
Crystal structure of Escherichia coli Orotate Phosphoribosyltransferase in complex with Orotic acid and Sulfate at 1.25 Angstrom resolution
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AAA | 0000287 | molecular_function | magnesium ion binding |
| AAA | 0004588 | molecular_function | orotate phosphoribosyltransferase activity |
| AAA | 0005737 | cellular_component | cytoplasm |
| AAA | 0005829 | cellular_component | cytosol |
| AAA | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| AAA | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| AAA | 0016740 | molecular_function | transferase activity |
| AAA | 0016757 | molecular_function | glycosyltransferase activity |
| AAA | 0042803 | molecular_function | protein homodimerization activity |
| AAA | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| AAA | 0046132 | biological_process | pyrimidine ribonucleoside biosynthetic process |
| BBB | 0000287 | molecular_function | magnesium ion binding |
| BBB | 0004588 | molecular_function | orotate phosphoribosyltransferase activity |
| BBB | 0005737 | cellular_component | cytoplasm |
| BBB | 0005829 | cellular_component | cytosol |
| BBB | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| BBB | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| BBB | 0016740 | molecular_function | transferase activity |
| BBB | 0016757 | molecular_function | glycosyltransferase activity |
| BBB | 0042803 | molecular_function | protein homodimerization activity |
| BBB | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| BBB | 0046132 | biological_process | pyrimidine ribonucleoside biosynthetic process |
Functional Information from PROSITE/UniProt
| site_id | PS00103 |
| Number of Residues | 13 |
| Details | PUR_PYR_PR_TRANSFER Purine/pyrimidine phosphoribosyl transferases signature. VMLVDDVITAGtA |
| Chain | Residue | Details |
| AAA | VAL120-ALA132 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"HAMAP-Rule","id":"MF_01208","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01208","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"HAMAP-Rule","id":"MF_01208","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8620002","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01208","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8620002","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
