Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6T9K

SAGA Core module

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000124	cellular_component	SAGA complex
B	0003712	molecular_function	transcription coregulator activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0006325	biological_process	chromatin organization
B	0006351	biological_process	DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0036498	biological_process	IRE1-mediated unfolded protein response
B	0046695	cellular_component	SLIK (SAGA-like) complex
C	0000124	cellular_component	SAGA complex
C	0001403	biological_process	invasive growth in response to glucose limitation
C	0003712	molecular_function	transcription coregulator activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006325	biological_process	chromatin organization
C	0006351	biological_process	DNA-templated transcription
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0006366	biological_process	transcription by RNA polymerase II
C	0007124	biological_process	pseudohyphal growth
C	0046695	cellular_component	SLIK (SAGA-like) complex
C	0046982	molecular_function	protein heterodimerization activity
D	0000124	cellular_component	SAGA complex
D	0003682	molecular_function	chromatin binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005669	cellular_component	transcription factor TFIID complex
D	0006325	biological_process	chromatin organization
D	0006351	biological_process	DNA-templated transcription
D	0006357	biological_process	regulation of transcription by RNA polymerase II
D	0006366	biological_process	transcription by RNA polymerase II
D	0006367	biological_process	transcription initiation at RNA polymerase II promoter
D	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
D	0042802	molecular_function	identical protein binding
D	0043130	molecular_function	ubiquitin binding
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0046695	cellular_component	SLIK (SAGA-like) complex
D	0060090	molecular_function	molecular adaptor activity
E	0000124	cellular_component	SAGA complex
E	0003682	molecular_function	chromatin binding
E	0003713	molecular_function	transcription coactivator activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005669	cellular_component	transcription factor TFIID complex
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006325	biological_process	chromatin organization
E	0006351	biological_process	DNA-templated transcription
E	0006357	biological_process	regulation of transcription by RNA polymerase II
E	0006366	biological_process	transcription by RNA polymerase II
E	0006367	biological_process	transcription initiation at RNA polymerase II promoter
E	0010468	biological_process	regulation of gene expression
E	0010557	biological_process	positive regulation of macromolecule biosynthetic process
E	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
E	0042802	molecular_function	identical protein binding
E	0045944	biological_process	positive regulation of transcription by RNA polymerase II
E	0046695	cellular_component	SLIK (SAGA-like) complex
E	0046982	molecular_function	protein heterodimerization activity
E	0051123	biological_process	RNA polymerase II preinitiation complex assembly
E	0060090	molecular_function	molecular adaptor activity
E	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
E	2000144	biological_process	positive regulation of DNA-templated transcription initiation
F	0000124	cellular_component	SAGA complex
F	0003682	molecular_function	chromatin binding
F	0003713	molecular_function	transcription coactivator activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005669	cellular_component	transcription factor TFIID complex
F	0006325	biological_process	chromatin organization
F	0006351	biological_process	DNA-templated transcription
F	0006352	biological_process	DNA-templated transcription initiation
F	0006357	biological_process	regulation of transcription by RNA polymerase II
F	0006366	biological_process	transcription by RNA polymerase II
F	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
F	0042802	molecular_function	identical protein binding
F	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0046695	cellular_component	SLIK (SAGA-like) complex
F	0046982	molecular_function	protein heterodimerization activity
F	0051123	biological_process	RNA polymerase II preinitiation complex assembly
F	0060090	molecular_function	molecular adaptor activity
G	0000124	cellular_component	SAGA complex
G	0003682	molecular_function	chromatin binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005669	cellular_component	transcription factor TFIID complex
G	0006325	biological_process	chromatin organization
G	0006351	biological_process	DNA-templated transcription
G	0006352	biological_process	DNA-templated transcription initiation
G	0006357	biological_process	regulation of transcription by RNA polymerase II
G	0006366	biological_process	transcription by RNA polymerase II
G	0006367	biological_process	transcription initiation at RNA polymerase II promoter
G	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
G	0042802	molecular_function	identical protein binding
G	0045944	biological_process	positive regulation of transcription by RNA polymerase II
G	0046695	cellular_component	SLIK (SAGA-like) complex
G	0051123	biological_process	RNA polymerase II preinitiation complex assembly
G	0060090	molecular_function	molecular adaptor activity
G	1990841	molecular_function	promoter-specific chromatin binding
H	0000124	cellular_component	SAGA complex
H	0003712	molecular_function	transcription coregulator activity
H	0003713	molecular_function	transcription coactivator activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0006325	biological_process	chromatin organization
H	0006351	biological_process	DNA-templated transcription
H	0006357	biological_process	regulation of transcription by RNA polymerase II
H	0006366	biological_process	transcription by RNA polymerase II
H	0045893	biological_process	positive regulation of DNA-templated transcription
H	0046695	cellular_component	SLIK (SAGA-like) complex
H	0070461	cellular_component	SAGA-type complex
I	0000124	cellular_component	SAGA complex
I	0003677	molecular_function	DNA binding
I	0003682	molecular_function	chromatin binding
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005669	cellular_component	transcription factor TFIID complex
I	0005777	cellular_component	peroxisome
I	0006325	biological_process	chromatin organization
I	0006351	biological_process	DNA-templated transcription
I	0006352	biological_process	DNA-templated transcription initiation
I	0006357	biological_process	regulation of transcription by RNA polymerase II
I	0006366	biological_process	transcription by RNA polymerase II
I	0017025	molecular_function	TBP-class protein binding
I	0042802	molecular_function	identical protein binding
I	0045944	biological_process	positive regulation of transcription by RNA polymerase II
I	0046695	cellular_component	SLIK (SAGA-like) complex
I	0046982	molecular_function	protein heterodimerization activity
I	0051123	biological_process	RNA polymerase II preinitiation complex assembly
I	0060090	molecular_function	molecular adaptor activity
I	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
I	0070461	cellular_component	SAGA-type complex
I	1905368	cellular_component	peptidase complex
K	0000124	cellular_component	SAGA complex
K	0000747	biological_process	conjugation with cellular fusion
K	0005198	molecular_function	structural molecule activity
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005739	cellular_component	mitochondrion
K	0006325	biological_process	chromatin organization
K	0006351	biological_process	DNA-templated transcription
K	0006357	biological_process	regulation of transcription by RNA polymerase II
K	0046695	cellular_component	SLIK (SAGA-like) complex
K	0046982	molecular_function	protein heterodimerization activity
K	0065003	biological_process	protein-containing complex assembly
Q	0000124	cellular_component	SAGA complex
Q	0004402	molecular_function	histone acetyltransferase activity
Q	0005198	molecular_function	structural molecule activity
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006325	biological_process	chromatin organization
Q	0006351	biological_process	DNA-templated transcription
Q	0006357	biological_process	regulation of transcription by RNA polymerase II
Q	0006406	biological_process	mRNA export from nucleus
Q	0008047	molecular_function	enzyme activator activity
Q	0008270	molecular_function	zinc ion binding
Q	0031048	biological_process	regulatory ncRNA-mediated heterochromatin formation
Q	0045899	biological_process	positive regulation of RNA polymerase II transcription preinitiation complex assembly
Q	0046695	cellular_component	SLIK (SAGA-like) complex
Q	0046822	biological_process	regulation of nucleocytoplasmic transport
Q	0065003	biological_process	protein-containing complex assembly
Q	0071819	cellular_component	DUBm complex
Q	1904802	biological_process	RITS complex assembly
Q	1905634	biological_process	regulation of protein localization to chromatin
U	0016172	molecular_function	antifreeze activity
U	0050825	molecular_function	ice binding

Functional Information from PROSITE/UniProt

site_id	PS00626
Number of Residues	11
Details	RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. ISGGaDHTVRV

Chain	Residue	Details
D	ILE710-VAL720

site_id	PS00633
Number of Residues	58
Details	BROMODOMAIN_1 Bromodomain signature. StpFlnkvSkreap..NYHqiIkksMdlntVlkklksfq..Ydskqefvddiml.IwkNCltY

Chain	Residue	Details
K	SER463-TYR520

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. VFTGssDkTCRMWDV

Chain	Residue	Details
D	VAL624-VAL638
D	LEU666-ILE680
D	LEU709-LEU723

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Domain: {"description":"LisH","evidences":[{"source":"PROSITE-ProRule","id":"PRU00126","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	39
Details	Repeat: {"description":"WD 1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	39
Details	Repeat: {"description":"WD 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	39
Details	Repeat: {"description":"WD 3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	39
Details	Repeat: {"description":"WD 4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	39
Details	Repeat: {"description":"WD 5","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	39
Details	Repeat: {"description":"WD 6","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	24
Details	Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	31
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)