6T8C

Crystal structure of formate dehydrogenase FDH2 enzyme from Granulicella mallensis MP5ACTX8 in the apo form.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005737	cellular_component	cytoplasm
A	0008863	molecular_function	formate dehydrogenase (NAD+) activity
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0032787	biological_process	monocarboxylic acid metabolic process
A	0042183	biological_process	formate catabolic process
A	0051287	molecular_function	NAD binding
B	0000166	molecular_function	nucleotide binding
B	0005737	cellular_component	cytoplasm
B	0008863	molecular_function	formate dehydrogenase (NAD+) activity
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0032787	biological_process	monocarboxylic acid metabolic process
B	0042183	biological_process	formate catabolic process
B	0051287	molecular_function	NAD binding
C	0000166	molecular_function	nucleotide binding
C	0005737	cellular_component	cytoplasm
C	0008863	molecular_function	formate dehydrogenase (NAD+) activity
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0032787	biological_process	monocarboxylic acid metabolic process
C	0042183	biological_process	formate catabolic process
C	0051287	molecular_function	NAD binding
D	0000166	molecular_function	nucleotide binding
D	0005737	cellular_component	cytoplasm
D	0008863	molecular_function	formate dehydrogenase (NAD+) activity
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0032787	biological_process	monocarboxylic acid metabolic process
D	0042183	biological_process	formate catabolic process
D	0051287	molecular_function	NAD binding

Functional Information from PROSITE/UniProt

site_id	PS00065
Number of Residues	28
Details	D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. VGTVAaGRIGlavlkrlkpfdvk.LHyFD

Chain	Residue	Details
A	VAL195-ASP222

---

site_id	PS00670
Number of Residues	23
Details	D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. MVkvCDVVtINaPlhpgTldLfN

Chain	Residue	Details
A	MET245-ASN267

---

site_id	PS00671
Number of Residues	17
Details	D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKrGaYLVNtARGkICN

Chain	Residue	Details
A	MET274-ASN290

---