6T88

Urocanate reductase in complex with imidazole propionate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0010181	molecular_function	FMN binding
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue GOL A 601

Chain	Residue
A	GLU150
A	HOH990
A	ALA153
A	TRP228
A	TYR232
A	ASP475
A	ARG574
A	HOH814
A	HOH821
A	HOH933

---

site_id	AC2
Number of Residues	8
Details	binding site for residue GOL A 602

Chain	Residue
A	ASP240
A	GLN241
A	ASP273
A	GLY276
A	PRO278
A	HOH1051
A	HOH1134
A	HOH1309

---

site_id	AC3
Number of Residues	12
Details	binding site for residue GOL A 603

Chain	Residue
A	GLU442
A	MET443
A	HIS444
A	GLN445
A	GLY446
A	ASP461
A	GLY508
A	PRO509
A	HOH721
A	HOH872
A	HOH1115
A	HOH1171

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 604

Chain	Residue
A	ASP454
A	LEU456
A	LYS514
A	HOH825

---

site_id	AC5
Number of Residues	8
Details	binding site for residue GOL A 605

Chain	Residue
A	ILE199
A	SER200
A	PHE404
A	HOH726
A	HOH747
A	HOH960
A	HOH995
A	HOH1321

---

site_id	AC6
Number of Residues	11
Details	binding site for residue GOL A 606

Chain	Residue
A	THR192
A	ASP193
A	SER194
A	LEU197
A	LYS492
A	ASP493
A	GLU494
A	ASN497
A	HOH781
A	HOH848
A	HOH1013

---

site_id	AC7
Number of Residues	44
Details	binding site for residue FAD A 607

Chain	Residue
A	ILE138
A	GLY139
A	GLY141
A	GLY142
A	ALA143
A	ILE161
A	GLU162
A	LYS163
A	MET164
A	GLY168
A	GLY169
A	ASN170
A	SER171
A	ILE173
A	SER174
A	GLY175
A	ALA176
A	GLU177
A	THR283
A	ALA285
A	ALA319
A	THR320
A	GLY321
A	THR344
A	HIS346
A	ASP352
A	ILE383
A	HIS520
A	HIS521
A	GLY549
A	GLU550
A	ARG560
A	GLY563
A	ASN564
A	ALA565
A	TYR566
A	ILE569
A	MWQ608
A	HOH778
A	HOH816
A	HOH844
A	HOH898
A	HOH969
A	HOH1010

---

site_id	AC8
Number of Residues	11
Details	binding site for residue MWQ A 608

Chain	Residue
A	TYR373
A	LEU385
A	ASP388
A	HIS520
A	ARG560
A	GLY562
A	GLY563
A	FAD607
A	HOH1018
A	GLU177
A	PHE245

---

site_id	AC9
Number of Residues	6
Details	binding site for residue NA A 609

Chain	Residue
A	THR522
A	MET523
A	GLY524
A	GLU550
A	THR552
A	HOH1064

---

site_id	AD1
Number of Residues	6
Details	binding site for residue CL A 610

Chain	Residue
A	MET189
A	GLN241
A	LEU242
A	LYS251
A	HOH833
A	HOH1131

---

site_id	AD2
Number of Residues	8
Details	binding site for residue CL A 611

Chain	Residue
A	GLY246
A	ARG410
A	ARG411
A	HOH704
A	HOH760
A	HOH1031
A	HOH1062
A	HOH1183

---

site_id	AD3
Number of Residues	6
Details	binding site for residue CL A 612

Chain	Residue
A	PHE245
A	GLY246
A	ARG411
A	GOL614
A	HOH704
A	HOH1018

---

site_id	AD4
Number of Residues	7
Details	binding site for residue GOL A 613

Chain	Residue
A	ILE279
A	HIS280
A	THR281
A	HIS303
A	HOH949
A	HOH1052
A	HOH1106

---

site_id	AD5
Number of Residues	8
Details	binding site for residue GOL A 614

Chain	Residue
A	GLN244
A	GLY246
A	ARG390
A	PHE391
A	LEU408
A	GLU409
A	CL612
A	HOH916

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P0C278","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P83223","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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