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6T7S

MexB structure solved by cryo-EM in nanodisc in absence of its protein partners

Functional Information from GO Data
ChainGOidnamespacecontents
J0005515molecular_functionprotein binding
J0005886cellular_componentplasma membrane
J0015562molecular_functionefflux transmembrane transporter activity
J0016020cellular_componentmembrane
J0022857molecular_functiontransmembrane transporter activity
J0042908biological_processxenobiotic transport
J0042910molecular_functionxenobiotic transmembrane transporter activity
J0046677biological_processresponse to antibiotic
J0055085biological_processtransmembrane transport
K0005515molecular_functionprotein binding
K0005886cellular_componentplasma membrane
K0015562molecular_functionefflux transmembrane transporter activity
K0016020cellular_componentmembrane
K0022857molecular_functiontransmembrane transporter activity
K0042908biological_processxenobiotic transport
K0042910molecular_functionxenobiotic transmembrane transporter activity
K0046677biological_processresponse to antibiotic
K0055085biological_processtransmembrane transport
L0005515molecular_functionprotein binding
L0005886cellular_componentplasma membrane
L0015562molecular_functionefflux transmembrane transporter activity
L0016020cellular_componentmembrane
L0022857molecular_functiontransmembrane transporter activity
L0042908biological_processxenobiotic transport
L0042910molecular_functionxenobiotic transmembrane transporter activity
L0046677biological_processresponse to antibiotic
L0055085biological_processtransmembrane transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues390
DetailsTOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:10187844
ChainResidueDetails
JMET1-PRO9
KGLU414-ALA441
KLEU497-ARG538
KGLU892-PRO897
KGLU946-PRO972
KSER1028-GLN1046
LMET1-PRO9
LGLN360-THR365
LGLU414-ALA441
LLEU497-ARG538
LGLU892-PRO897
JGLN360-THR365
LGLU946-PRO972
LSER1028-GLN1046
JGLU414-ALA441
JLEU497-ARG538
JGLU892-PRO897
JGLU946-PRO972
JSER1028-GLN1046
KMET1-PRO9
KGLN360-THR365

site_idSWS_FT_FI2
Number of Residues702
DetailsTRANSMEM: Helical
ChainResidueDetails
JILE10-LEU28
JVAL924-VAL945
JILE973-THR991
JVAL1005-VAL1027
KILE10-LEU28
KVAL340-LEU359
KLEU366-ALA385
KTHR392-VAL413
KLEU442-GLY460
KILE474-MET496
KALA539-THR557
JVAL340-LEU359
KALA872-TYR891
KPHE898-MET917
KVAL924-VAL945
KILE973-THR991
KVAL1005-VAL1027
LILE10-LEU28
LVAL340-LEU359
LLEU366-ALA385
LTHR392-VAL413
LLEU442-GLY460
JLEU366-ALA385
LILE474-MET496
LALA539-THR557
LALA872-TYR891
LPHE898-MET917
LVAL924-VAL945
LILE973-THR991
LVAL1005-VAL1027
JTHR392-VAL413
JLEU442-GLY460
JILE474-MET496
JALA539-THR557
JALA872-TYR891
JPHE898-MET917

site_idSWS_FT_FI3
Number of Residues1971
DetailsTOPO_DOM: Periplasmic => ECO:0000269|PubMed:10187844
ChainResidueDetails
JSER29-GLU339
KARG558-GLN871
KARG918-ASP923
KGLY992-GLY1004
LSER29-GLU339
LPHE386-ASN391
LGLY461-THR473
LARG558-GLN871
LARG918-ASP923
LGLY992-GLY1004
JPHE386-ASN391
JGLY461-THR473
JARG558-GLN871
JARG918-ASP923
JGLY992-GLY1004
KSER29-GLU339
KPHE386-ASN391
KGLY461-THR473

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PDB entries from 2024-07-31

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