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6T7S

MexB structure solved by cryo-EM in nanodisc in absence of its protein partners

Functional Information from GO Data
ChainGOidnamespacecontents
J0005515molecular_functionprotein binding
J0005886cellular_componentplasma membrane
J0009636biological_processresponse to toxic substance
J0015297molecular_functionantiporter activity
J0015562molecular_functionefflux transmembrane transporter activity
J0016020cellular_componentmembrane
J0022857molecular_functiontransmembrane transporter activity
J0042908biological_processxenobiotic transport
J0042910molecular_functionxenobiotic transmembrane transporter activity
J0046677biological_processresponse to antibiotic
J0055085biological_processtransmembrane transport
J0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
J1990281cellular_componentefflux pump complex
K0005515molecular_functionprotein binding
K0005886cellular_componentplasma membrane
K0009636biological_processresponse to toxic substance
K0015297molecular_functionantiporter activity
K0015562molecular_functionefflux transmembrane transporter activity
K0016020cellular_componentmembrane
K0022857molecular_functiontransmembrane transporter activity
K0042908biological_processxenobiotic transport
K0042910molecular_functionxenobiotic transmembrane transporter activity
K0046677biological_processresponse to antibiotic
K0055085biological_processtransmembrane transport
K0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
K1990281cellular_componentefflux pump complex
L0005515molecular_functionprotein binding
L0005886cellular_componentplasma membrane
L0009636biological_processresponse to toxic substance
L0015297molecular_functionantiporter activity
L0015562molecular_functionefflux transmembrane transporter activity
L0016020cellular_componentmembrane
L0022857molecular_functiontransmembrane transporter activity
L0042908biological_processxenobiotic transport
L0042910molecular_functionxenobiotic transmembrane transporter activity
L0046677biological_processresponse to antibiotic
L0055085biological_processtransmembrane transport
L0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
L1990281cellular_componentefflux pump complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI2
Number of Residues702
DetailsTransmembrane: {"description":"Helical"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues336
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"10187844","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues1971
DetailsTopological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"10187844","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

246704

PDB entries from 2025-12-24

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