6T7J
As-isolated Ni-free crystal structure of carbon monoxide dehydrogenase from Thermococcus sp. AM4 produced without CooC maturase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0006091 | biological_process | generation of precursor metabolites and energy |
| A | 0016151 | molecular_function | nickel cation binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0043885 | molecular_function | anaerobic carbon-monoxide dehydrogenase activity |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0006091 | biological_process | generation of precursor metabolites and energy |
| B | 0016151 | molecular_function | nickel cation binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0043885 | molecular_function | anaerobic carbon-monoxide dehydrogenase activity |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0006091 | biological_process | generation of precursor metabolites and energy |
| D | 0016151 | molecular_function | nickel cation binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0043885 | molecular_function | anaerobic carbon-monoxide dehydrogenase activity |
| D | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 B 701 |
| Chain | Residue |
| B | CYS55 |
| B | CYS58 |
| B | MET60 |
| B | GLY61 |
| B | CYS63 |
| B | CYS77 |
| B | ARG87 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue FES B 702 |
| Chain | Residue |
| B | CYS54 |
| B | ARG56 |
| B | ARG64 |
| B | CYS46 |
| B | GLY49 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue MSK B 703 |
| Chain | Residue |
| B | HIS269 |
| B | CYS305 |
| B | PHE322 |
| B | CYS343 |
| B | GLY450 |
| B | CYS451 |
| B | CYS481 |
| B | CYS522 |
| B | MET556 |
| B | SER557 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 B 704 |
| Chain | Residue |
| A | LYS258 |
| A | LYS410 |
| B | GLU22 |
| B | HIS409 |
| B | HOH802 |
| B | HOH830 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue BU3 B 705 |
| Chain | Residue |
| B | THR361 |
| B | HIS367 |
| B | ILE368 |
| B | ALA371 |
| B | HIS373 |
| B | LEU632 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue BU3 B 706 |
| Chain | Residue |
| B | ARG438 |
| B | LEU539 |
| B | LEU628 |
| B | TRP630 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue BU3 B 707 |
| Chain | Residue |
| A | PO4704 |
| A | CIT705 |
| B | LYS258 |
| B | GLU259 |
| B | ASP260 |
| B | TYR261 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 708 |
| Chain | Residue |
| B | THR593 |
| B | LYS603 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 A 701 |
| Chain | Residue |
| A | CYS55 |
| A | ASN57 |
| A | CYS58 |
| A | MET60 |
| A | GLY61 |
| A | CYS63 |
| A | VAL76 |
| A | CYS77 |
| A | ARG87 |
| A | ILE206 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue FES A 702 |
| Chain | Residue |
| A | CYS46 |
| A | CYS54 |
| D | ARG56 |
| D | FES702 |
| site_id | AD2 |
| Number of Residues | 11 |
| Details | binding site for residue MSK A 703 |
| Chain | Residue |
| A | HIS269 |
| A | CYS304 |
| A | CYS305 |
| A | PHE322 |
| A | CYS343 |
| A | GLY450 |
| A | CYS451 |
| A | CYS481 |
| A | CYS522 |
| A | MET556 |
| A | SER557 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 A 704 |
| Chain | Residue |
| A | HIS409 |
| B | GLU259 |
| B | BU3707 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue CIT A 705 |
| Chain | Residue |
| A | LYS18 |
| A | GLY19 |
| A | GLU22 |
| A | HIS409 |
| B | ASP260 |
| B | LYS296 |
| B | BU3707 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 D 701 |
| Chain | Residue |
| D | CYS55 |
| D | CYS58 |
| D | MET60 |
| D | GLY61 |
| D | CYS63 |
| D | VAL76 |
| D | CYS77 |
| D | ARG87 |
| D | ILE206 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue FES D 702 |
| Chain | Residue |
| A | CYS54 |
| A | FES702 |
| D | CYS46 |
| D | CYS54 |
| D | ARG56 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue MSK D 703 |
| Chain | Residue |
| D | GLY450 |
| D | CYS451 |
| D | CYS481 |
| D | CYS522 |
| D | MET556 |
| D | HIS269 |
| D | CYS305 |
| D | PHE322 |
| D | CYS343 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 D 704 |
| Chain | Residue |
| D | GLY187 |
| D | SER214 |
| D | ARG221 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 D 705 |
| Chain | Residue |
| D | LYS18 |
| D | GLU22 |
| D | LYS296 |
| D | HIS409 |
