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6T77

Crystal structure of Klebsiella pneumoniae FabG(NADPH-dependent) NADP-complex at 1.75 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
A0006633biological_processfatty acid biosynthetic process
A0016491molecular_functionoxidoreductase activity
A0051287molecular_functionNAD binding
B0000166molecular_functionnucleotide binding
B0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
B0006633biological_processfatty acid biosynthetic process
B0016491molecular_functionoxidoreductase activity
B0051287molecular_functionNAD binding
Functional Information from PDB Data
site_idAC1
Number of Residues16
Detailsbinding site for residue NAP A 301
ChainResidue
AGLY12
AILE89
AHOH406
AHOH411
AHOH434
AHOH459
AHOH489
AHOH490
ASER14
AARG15
ATHR37
ALEU58
AASN59
AVAL60
AALA87
AGLY88

site_idAC2
Number of Residues27
Detailsbinding site for residue NAP B 301
ChainResidue
BGLY12
BSER14
BARG15
BALA36
BTHR37
BLEU58
BASN59
BVAL60
BASN86
BALA87
BGLY88
BILE89
BLYS99
BILE136
BGLY137
BTYR151
BLYS155
BPRO181
BGLY182
BILE184
BHOH402
BHOH407
BHOH430
BHOH439
BHOH456
BHOH458
BHOH485

Functional Information from PROSITE/UniProt
site_idPS00061
Number of Residues29
DetailsADH_SHORT Short-chain dehydrogenases/reductases family signature. SvvgtmgnagQanYAAAKAGLiGFSkSLA
ChainResidueDetails
ASER138-ALA166

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PDB entries from 2024-06-12

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