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6T62

Crystal structure of Acinetobacter baumannii FabG in complex with NADPH at 1.8 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
A0006633biological_processfatty acid biosynthetic process
A0016491molecular_functionoxidoreductase activity
A0051287molecular_functionNAD binding
B0000166molecular_functionnucleotide binding
B0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
B0006633biological_processfatty acid biosynthetic process
B0016491molecular_functionoxidoreductase activity
B0051287molecular_functionNAD binding
Functional Information from PDB Data
site_idAC1
Number of Residues30
Detailsbinding site for residue NAP A 301
ChainResidue
AGLY12
AALA87
AGLY88
AILE136
ASER137
ASER138
ATYR151
ALYS155
APRO181
AGLY182
AILE184
ASER14
ATHR186
AMET188
AHOH401
AHOH410
AHOH428
AHOH439
AHOH487
AHOH503
AHOH530
AHOH533
AARG15
AHOH544
AALA36
ATHR37
ALEU58
AASP59
AVAL60
AASN86

site_idAC2
Number of Residues27
Detailsbinding site for residue NAP B 301
ChainResidue
BGLY12
BSER14
BARG15
BILE17
BTHR37
BLEU58
BASP59
BVAL60
BASN86
BALA87
BGLY88
BILE89
BHIS110
BILE136
BSER137
BSER138
BTYR151
BLYS155
BPRO181
BGLY182
BILE184
BTHR186
BHOH402
BHOH417
BHOH433
BHOH439
BHOH458

Functional Information from PROSITE/UniProt
site_idPS00061
Number of Residues29
DetailsADH_SHORT Short-chain dehydrogenases/reductases family signature. SvvahfanpgQanYSAAKAGIeAFSrSLA
ChainResidueDetails
ASER138-ALA166

226707

PDB entries from 2024-10-30

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