6T4W

ROR(gamma)t ligand binding domain in complex with 20-alpha-hydroxycholesterol and allosteric ligand Glenmark

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue GOL A 801

Chain	Residue
A	PHE377
A	PHE378
A	GLU379
A	HOH905
A	HOH958

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site_id	AC2
Number of Residues	4
Details	binding site for residue GOL A 802

Chain	Residue
A	GLN349
A	ILE350
A	LEU353
A	PRO500

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site_id	AC3
Number of Residues	17
Details	binding site for residue MJE A 803

Chain	Residue
A	TRP317
A	LEU324
A	THR325
A	ILE328
A	GLN329
A	LEU353
A	LYS354
A	MET358
A	LEU483
A	GLN484
A	GLN495
A	ALA496
A	ALA497
A	PHE498
A	TYR502
A	LEU505
A	PHE506

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site_id	AC4
Number of Residues	5
Details	binding site for residue HCD A 804

Chain	Residue
A	GLN286
A	HIS323
A	PHE388
A	LEU396
A	HIS479

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