6T4V

Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in apo form.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0004451	molecular_function	isocitrate lyase activity
A	0019543	biological_process	propionate catabolic process
A	0046421	molecular_function	methylisocitrate lyase activity
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0004451	molecular_function	isocitrate lyase activity
B	0019543	biological_process	propionate catabolic process
B	0046421	molecular_function	methylisocitrate lyase activity
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0004451	molecular_function	isocitrate lyase activity
C	0019543	biological_process	propionate catabolic process
C	0046421	molecular_function	methylisocitrate lyase activity
D	0000287	molecular_function	magnesium ion binding
D	0003824	molecular_function	catalytic activity
D	0004451	molecular_function	isocitrate lyase activity
D	0019543	biological_process	propionate catabolic process
D	0046421	molecular_function	methylisocitrate lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue PYR C 301

site_id	AC2
Number of Residues	6
Details	binding site for residue PYR A 301

site_id	AC3
Number of Residues	6
Details	binding site for residue PYR B 301

site_id	AC4
Number of Residues	6
Details	binding site for residue PYR D 301

Functional Information from PROSITE/UniProt

site_id	PS00161
Number of Residues	6
Details	ISOCITRATE_LYASE Isocitrate lyase signature. KRCGHR

Chain	Residue	Details
C	LYS123-ARG128