6T2T
Crystal structure of Drosophila melanogaster glutathione S-transferase epsilon 14 in complex with glutathione and 2-methyl-2,4-pentanediol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0004769 | molecular_function | steroid delta-isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006694 | biological_process | steroid biosynthetic process |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0009636 | biological_process | response to toxic substance |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042632 | biological_process | cholesterol homeostasis |
| A | 0045456 | biological_process | ecdysteroid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue GSH A 301 |
| Chain | Residue |
| A | SER14 |
| A | HIS71 |
| A | SER107 |
| A | PHE110 |
| A | MPD302 |
| A | HOH428 |
| A | HOH453 |
| A | HOH469 |
| A | HOH470 |
| A | HOH524 |
| A | HOH530 |
| A | LEU38 |
| A | HOH566 |
| A | GLN43 |
| A | HIS55 |
| A | SER56 |
| A | VAL57 |
| A | PRO58 |
| A | ASP69 |
| A | SER70 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MPD A 302 |
| Chain | Residue |
| A | PRO15 |
| A | MET117 |
| A | SER118 |
| A | GSH301 |
| A | HOH424 |
| A | HOH565 |
