6SZU
Bat Influenza A polymerase pre-termination complex with pyrophosphate using 44-mer vRNA template with mutated oligo(U) sequence
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0039694 | biological_process | viral RNA genome replication |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0001172 | biological_process | RNA-templated transcription |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0019083 | biological_process | viral transcription |
| B | 0030430 | cellular_component | host cell cytoplasm |
| B | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
| B | 0039523 | biological_process | symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity |
| B | 0039694 | biological_process | viral RNA genome replication |
| B | 0042025 | cellular_component | host cell nucleus |
| C | 0003723 | molecular_function | RNA binding |
| C | 0006351 | biological_process | DNA-templated transcription |
| C | 0006370 | biological_process | 7-methylguanosine mRNA capping |
| C | 0019083 | biological_process | viral transcription |
| C | 0033650 | cellular_component | host cell mitochondrion |
| C | 0039523 | biological_process | symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity |
| C | 0042025 | cellular_component | host cell nucleus |
| C | 0044423 | cellular_component | virion component |
| C | 0075526 | biological_process | cap snatching |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue M4H A 801 |
| Chain | Residue |
| A | TYR24 |
| A | MG802 |
| A | MG803 |
| A | ALA37 |
| A | ILE38 |
| A | HIS41 |
| A | GLU80 |
| A | ASP108 |
| A | GLU119 |
| A | ILE120 |
| A | LYS134 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 802 |
| Chain | Residue |
| A | GLU80 |
| A | LEU106 |
| A | PRO107 |
| A | ASP108 |
| A | M4H801 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 803 |
| Chain | Residue |
| A | HIS41 |
| A | ASP108 |
| A | GLU119 |
| A | ILE120 |
| A | M4H801 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 801 |
| Chain | Residue |
| B | ASP305 |
| B | ASP445 |
| B | ASP446 |
| B | HOH1021 |
| M | C36 |
| M | A37 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 802 |
| Chain | Residue |
| B | ASP305 |
| B | ASN306 |
| B | ASP445 |
| B | POP803 |
| M | A37 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue POP B 803 |
| Chain | Residue |
| B | ARG239 |
| B | ASP305 |
| B | ASN306 |
| B | LYS308 |
| B | TRP309 |
| B | ASN310 |
| B | ASP445 |
| B | LYS481 |
| B | MG802 |
| B | HOH929 |
| B | HOH971 |
| M | A37 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue MG V 101 |
| Chain | Residue |
| V | U3 |
| V | HOH209 |
| V | HOH230 |
| V | HOH252 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue MG M 101 |
| Chain | Residue |
| M | G32 |
| M | A33 |
| M | HOH202 |
