6SX7
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) (2.2 Angstrom resolution)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001518 | cellular_component | voltage-gated sodium channel complex |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005248 | molecular_function | voltage-gated sodium channel activity |
| A | 0005261 | molecular_function | monoatomic cation channel activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0035725 | biological_process | sodium ion transmembrane transport |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0098655 | biological_process | monoatomic cation transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 302 |
| Chain | Residue |
| A | NA303 |
| A | NA303 |
| A | NA303 |
| A | NA303 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue NA A 303 |
| Chain | Residue |
| A | NA302 |
| A | NA302 |
| A | NA302 |
| A | SER179 |
| A | SER179 |
| A | SER179 |
| A | SER179 |
| A | NA302 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue 2CV A 304 |
| Chain | Residue |
| A | PHE142 |
| A | SER165 |
| A | LYS166 |
| A | TYR169 |
| A | MET189 |
| A | ASN190 |
| A | TRP196 |
| A | HOH401 |
| A | HOH406 |
| A | HOH425 |
| A | HOH426 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue 12P A 305 |
| Chain | Residue |
| A | PHE102 |
| A | VAL141 |
| A | LEU152 |
| A | TYR153 |
| A | HIS192 |
| A | ASN194 |
| A | VAL197 |
| A | HOH429 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue 2CV A 307 |
| Chain | Residue |
| A | MET175 |
| A | THR207 |
