6SU1
Trypanosoma congolense pyruvate kinase in complex with citrate and glycerol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004743 | molecular_function | pyruvate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030955 | molecular_function | potassium ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004743 | molecular_function | pyruvate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030955 | molecular_function | potassium ion binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004743 | molecular_function | pyruvate kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006096 | biological_process | glycolytic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0030955 | molecular_function | potassium ion binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004743 | molecular_function | pyruvate kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006096 | biological_process | glycolytic process |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0030955 | molecular_function | potassium ion binding |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004743 | molecular_function | pyruvate kinase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0006096 | biological_process | glycolytic process |
| E | 0016301 | molecular_function | kinase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0030955 | molecular_function | potassium ion binding |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004743 | molecular_function | pyruvate kinase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0006096 | biological_process | glycolytic process |
| F | 0016301 | molecular_function | kinase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0030955 | molecular_function | potassium ion binding |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0004743 | molecular_function | pyruvate kinase activity |
| G | 0005524 | molecular_function | ATP binding |
| G | 0006096 | biological_process | glycolytic process |
| G | 0016301 | molecular_function | kinase activity |
| G | 0016740 | molecular_function | transferase activity |
| G | 0030955 | molecular_function | potassium ion binding |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0000287 | molecular_function | magnesium ion binding |
| H | 0003824 | molecular_function | catalytic activity |
| H | 0004743 | molecular_function | pyruvate kinase activity |
| H | 0005524 | molecular_function | ATP binding |
| H | 0006096 | biological_process | glycolytic process |
| H | 0016301 | molecular_function | kinase activity |
| H | 0016740 | molecular_function | transferase activity |
| H | 0030955 | molecular_function | potassium ion binding |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 601 |
| Chain | Residue |
| A | ARG425 |
| A | LEU426 |
| A | LEU427 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 602 |
| Chain | Residue |
| A | TYR489 |
| A | SER401 |
| A | ASN402 |
| A | THR403 |
| A | GLY404 |
| A | ARG405 |
| A | SER406 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue CIT B 601 |
| Chain | Residue |
| B | ARG50 |
| B | ASN52 |
| B | SER54 |
| B | ASP84 |
| B | LYS239 |
| B | GLU241 |
| B | ALA262 |
| B | ARG263 |
| B | GLY264 |
| B | ASP265 |
| B | THR297 |
| B | SER331 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 602 |
| Chain | Residue |
| B | GLU378 |
| B | SER401 |
| B | THR403 |
| B | ARG405 |
| B | SER406 |
| B | GLY488 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CIT C 601 |
| Chain | Residue |
| C | ARG50 |
| C | ASN52 |
| C | LYS239 |
| C | SER331 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 602 |
| Chain | Residue |
| C | HIS481 |
| C | GLN492 |
| C | ARG494 |
| C | HOH705 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 603 |
| Chain | Residue |
| C | GLU378 |
| C | SER401 |
| C | ASN402 |
| C | THR403 |
| C | ARG405 |
| C | SER406 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue CIT D 601 |
| Chain | Residue |
| D | ARG50 |
| D | ASN52 |
| D | SER54 |
| D | HIS55 |
| D | ASP84 |
| D | GLU89 |
| D | LYS239 |
| D | GLU241 |
| D | ASP265 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 602 |
| Chain | Residue |
| D | LEU400 |
| D | SER401 |
| D | ASN402 |
| D | THR403 |
| D | SER406 |
| D | GLY488 |
| site_id | AD1 |
| Number of Residues | 12 |
| Details | binding site for residue CIT E 601 |
| Chain | Residue |
| E | ARG50 |
| E | ASN52 |
| E | SER54 |
| E | LYS239 |
| E | GLU241 |
| E | MET260 |
| E | ALA262 |
| E | ARG263 |
| E | GLY264 |
| E | ASP265 |
| E | THR297 |
| E | HOH703 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL E 602 |
| Chain | Residue |
| E | SER401 |
| E | ASN402 |
| E | THR403 |
| E | ARG405 |
| E | SER406 |
| site_id | AD3 |
| Number of Residues | 10 |
| Details | binding site for residue CIT F 601 |
| Chain | Residue |
| F | ARG50 |
| F | ASN52 |
| F | SER54 |
| F | GLU89 |
| F | ALA262 |
| F | ARG263 |
| F | GLY264 |
| F | ASP265 |
| F | THR297 |
| F | SER331 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL F 602 |
| Chain | Residue |
| F | LEU400 |
| F | SER401 |
| F | ASN402 |
| F | ARG405 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue PGE F 603 |
| Chain | Residue |
| F | ASP97 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL G 601 |
| Chain | Residue |
| G | GLU378 |
| G | SER401 |
| G | ASN402 |
| G | THR403 |
| G | SER406 |
| G | GLY488 |
| G | TYR489 |
| G | PRO490 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue CIT H 601 |
| Chain | Residue |
| H | ARG91 |
| H | LYS239 |
| H | GLU241 |
| H | ALA262 |
| H | ASP265 |
| H | THR297 |
| H | ARG50 |
| H | ASN52 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL H 602 |
| Chain | Residue |
| H | SER401 |
| H | ASN402 |
| H | THR403 |
| H | ARG405 |
| H | SER406 |
| H | TYR489 |
