6SPZ
Crystal structure of PDZ1-2 from PSD-95 with peptide ligand sequence RRESEI bound to both domains
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue GSH A 301 |
| Chain | Residue |
| A | THR67 |
| A | VAL238 |
| A | TYR240 |
| A | HOH430 |
| A | GLU69 |
| A | ASP108 |
| A | ARG110 |
| A | ASN121 |
| A | GLU122 |
| A | ARG145 |
| A | TYR147 |
| A | LYS162 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 86 |
| Details | Domain: {"description":"PDZ 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 86 |
| Details | Domain: {"description":"PDZ 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q62108","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q62108","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Motif: {"description":"PDZ-binding","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
