6SPK

A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 6

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000302	biological_process	response to reactive oxygen species
A	0000303	biological_process	response to superoxide
A	0001541	biological_process	ovarian follicle development
A	0001819	biological_process	positive regulation of cytokine production
A	0001890	biological_process	placenta development
A	0001895	biological_process	retina homeostasis
A	0002262	biological_process	myeloid cell homeostasis
A	0004784	molecular_function	superoxide dismutase activity
A	0005507	molecular_function	copper ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005759	cellular_component	mitochondrial matrix
A	0005777	cellular_component	peroxisome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006749	biological_process	glutathione metabolic process
A	0006801	biological_process	superoxide metabolic process
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006915	biological_process	apoptotic process
A	0006979	biological_process	response to oxidative stress
A	0007283	biological_process	spermatogenesis
A	0007566	biological_process	embryo implantation
A	0007605	biological_process	sensory perception of sound
A	0007626	biological_process	locomotory behavior
A	0008089	biological_process	anterograde axonal transport
A	0008090	biological_process	retrograde axonal transport
A	0008217	biological_process	regulation of blood pressure
A	0008270	molecular_function	zinc ion binding
A	0008340	biological_process	determination of adult lifespan
A	0009408	biological_process	response to heat
A	0009410	biological_process	response to xenobiotic stimulus
A	0010467	biological_process	gene expression
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0019226	biological_process	transmission of nerve impulse
A	0019228	biological_process	neuronal action potential
A	0019430	biological_process	removal of superoxide radicals
A	0030346	molecular_function	protein phosphatase 2B binding
A	0031267	molecular_function	small GTPase binding
A	0031410	cellular_component	cytoplasmic vesicle
A	0032287	biological_process	peripheral nervous system myelin maintenance
A	0032839	cellular_component	dendrite cytoplasm
A	0032930	biological_process	positive regulation of superoxide anion generation
A	0032991	cellular_component	protein-containing complex
A	0033081	biological_process	regulation of T cell differentiation in thymus
A	0035234	biological_process	ectopic germ cell programmed cell death
A	0040014	biological_process	regulation of multicellular organism growth
A	0042542	biological_process	response to hydrogen peroxide
A	0042554	biological_process	superoxide anion generation
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0043025	cellular_component	neuronal cell body
A	0043065	biological_process	positive regulation of apoptotic process
A	0043066	biological_process	negative regulation of apoptotic process
A	0043087	biological_process	regulation of GTPase activity
A	0043410	biological_process	positive regulation of MAPK cascade
A	0043524	biological_process	negative regulation of neuron apoptotic process
A	0045471	biological_process	response to ethanol
A	0046620	biological_process	regulation of organ growth
A	0046716	biological_process	muscle cell cellular homeostasis
A	0046872	molecular_function	metal ion binding
A	0048538	biological_process	thymus development
A	0048678	biological_process	response to axon injury
A	0050665	biological_process	hydrogen peroxide biosynthetic process
A	0050728	biological_process	negative regulation of inflammatory response
A	0050766	biological_process	positive regulation of phagocytosis
A	0051087	molecular_function	protein-folding chaperone binding
A	0051093	biological_process	negative regulation of developmental process
A	0051881	biological_process	regulation of mitochondrial membrane potential
A	0060047	biological_process	heart contraction
A	0060052	biological_process	neurofilament cytoskeleton organization
A	0060087	biological_process	relaxation of vascular associated smooth muscle
A	0060088	biological_process	auditory receptor cell stereocilium organization
A	0070062	cellular_component	extracellular exosome
A	0072593	biological_process	reactive oxygen species metabolic process
A	0099610	biological_process	action potential initiation
A	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
A	1904115	cellular_component	axon cytoplasm
A	2000242	biological_process	negative regulation of reproductive process
B	0000302	biological_process	response to reactive oxygen species
B	0000303	biological_process	response to superoxide
B	0001541	biological_process	ovarian follicle development
B	0001819	biological_process	positive regulation of cytokine production
B	0001890	biological_process	placenta development
B	0001895	biological_process	retina homeostasis
B	0002262	biological_process	myeloid cell homeostasis
B	0004784	molecular_function	superoxide dismutase activity
B	0005507	molecular_function	copper ion binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005758	cellular_component	mitochondrial intermembrane space
B	0005759	cellular_component	mitochondrial matrix
B	0005777	cellular_component	peroxisome
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006749	biological_process	glutathione metabolic process
B	0006801	biological_process	superoxide metabolic process
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006915	biological_process	apoptotic process
B	0006979	biological_process	response to oxidative stress
B	0007283	biological_process	spermatogenesis
B	0007566	biological_process	embryo implantation
B	0007605	biological_process	sensory perception of sound
B	0007626	biological_process	locomotory behavior
B	0008089	biological_process	anterograde axonal transport
B	0008090	biological_process	retrograde axonal transport
B	0008217	biological_process	regulation of blood pressure
B	0008270	molecular_function	zinc ion binding
B	0008340	biological_process	determination of adult lifespan
B	0009408	biological_process	response to heat
B	0009410	biological_process	response to xenobiotic stimulus
B	0010467	biological_process	gene expression
B	0016209	molecular_function	antioxidant activity
B	0016491	molecular_function	oxidoreductase activity
B	0019226	biological_process	transmission of nerve impulse
B	0019228	biological_process	neuronal action potential
B	0019430	biological_process	removal of superoxide radicals
B	0030346	molecular_function	protein phosphatase 2B binding
B	0031267	molecular_function	small GTPase binding
B	0031410	cellular_component	cytoplasmic vesicle
B	0032287	biological_process	peripheral nervous system myelin maintenance
B	0032839	cellular_component	dendrite cytoplasm
B	0032930	biological_process	positive regulation of superoxide anion generation
B	0032991	cellular_component	protein-containing complex
B	0033081	biological_process	regulation of T cell differentiation in thymus
B	0035234	biological_process	ectopic germ cell programmed cell death
B	0040014	biological_process	regulation of multicellular organism growth
B	0042542	biological_process	response to hydrogen peroxide
B	0042554	biological_process	superoxide anion generation
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0043025	cellular_component	neuronal cell body
B	0043065	biological_process	positive regulation of apoptotic process
B	0043066	biological_process	negative regulation of apoptotic process
B	0043087	biological_process	regulation of GTPase activity
B	0043410	biological_process	positive regulation of MAPK cascade
B	0043524	biological_process	negative regulation of neuron apoptotic process
B	0045471	biological_process	response to ethanol
B	0046620	biological_process	regulation of organ growth
B	0046716	biological_process	muscle cell cellular homeostasis
B	0046872	molecular_function	metal ion binding
B	0048538	biological_process	thymus development
B	0048678	biological_process	response to axon injury
B	0050665	biological_process	hydrogen peroxide biosynthetic process
B	0050728	biological_process	negative regulation of inflammatory response
B	0050766	biological_process	positive regulation of phagocytosis
B	0051087	molecular_function	protein-folding chaperone binding
B	0051093	biological_process	negative regulation of developmental process
B	0051881	biological_process	regulation of mitochondrial membrane potential
B	0060047	biological_process	heart contraction
B	0060052	biological_process	neurofilament cytoskeleton organization
B	0060087	biological_process	relaxation of vascular associated smooth muscle
B	0060088	biological_process	auditory receptor cell stereocilium organization
B	0070062	cellular_component	extracellular exosome
B	0072593	biological_process	reactive oxygen species metabolic process
B	0099610	biological_process	action potential initiation
B	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
B	1904115	cellular_component	axon cytoplasm
B	2000242	biological_process	negative regulation of reproductive process
E	0000302	biological_process	response to reactive oxygen species
E	0000303	biological_process	response to superoxide
E	0001541	biological_process	ovarian follicle development
E	0001819	biological_process	positive regulation of cytokine production
E	0001890	biological_process	placenta development
E	0001895	biological_process	retina homeostasis
E	0002262	biological_process	myeloid cell homeostasis
E	0004784	molecular_function	superoxide dismutase activity
E	0005507	molecular_function	copper ion binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005758	cellular_component	mitochondrial intermembrane space
E	0005759	cellular_component	mitochondrial matrix
E	0005777	cellular_component	peroxisome
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006749	biological_process	glutathione metabolic process
E	0006801	biological_process	superoxide metabolic process
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006915	biological_process	apoptotic process
E	0006979	biological_process	response to oxidative stress
E	0007283	biological_process	spermatogenesis
E	0007566	biological_process	embryo implantation
E	0007605	biological_process	sensory perception of sound
E	0007626	biological_process	locomotory behavior
E	0008089	biological_process	anterograde axonal transport
E	0008090	biological_process	retrograde axonal transport
E	0008217	biological_process	regulation of blood pressure
E	0008270	molecular_function	zinc ion binding
E	0008340	biological_process	determination of adult lifespan
E	0009408	biological_process	response to heat
E	0009410	biological_process	response to xenobiotic stimulus
E	0010467	biological_process	gene expression
E	0016209	molecular_function	antioxidant activity
E	0016491	molecular_function	oxidoreductase activity
E	0019226	biological_process	transmission of nerve impulse
E	0019228	biological_process	neuronal action potential
E	0019430	biological_process	removal of superoxide radicals
E	0030346	molecular_function	protein phosphatase 2B binding
E	0031267	molecular_function	small GTPase binding
E	0031410	cellular_component	cytoplasmic vesicle
E	0032287	biological_process	peripheral nervous system myelin maintenance
E	0032839	cellular_component	dendrite cytoplasm
E	0032930	biological_process	positive regulation of superoxide anion generation
E	0032991	cellular_component	protein-containing complex
E	0033081	biological_process	regulation of T cell differentiation in thymus
E	0035234	biological_process	ectopic germ cell programmed cell death
E	0040014	biological_process	regulation of multicellular organism growth
E	0042542	biological_process	response to hydrogen peroxide
E	0042554	biological_process	superoxide anion generation
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0043025	cellular_component	neuronal cell body
E	0043065	biological_process	positive regulation of apoptotic process
E	0043066	biological_process	negative regulation of apoptotic process
E	0043087	biological_process	regulation of GTPase activity
E	0043410	biological_process	positive regulation of MAPK cascade
E	0043524	biological_process	negative regulation of neuron apoptotic process
E	0045471	biological_process	response to ethanol
E	0046620	biological_process	regulation of organ growth
E	0046716	biological_process	muscle cell cellular homeostasis
E	0046872	molecular_function	metal ion binding
E	0048538	biological_process	thymus development
E	0048678	biological_process	response to axon injury
E	0050665	biological_process	hydrogen peroxide biosynthetic process
E	0050728	biological_process	negative regulation of inflammatory response
E	0050766	biological_process	positive regulation of phagocytosis
E	0051087	molecular_function	protein-folding chaperone binding
E	0051093	biological_process	negative regulation of developmental process
E	0051881	biological_process	regulation of mitochondrial membrane potential
E	0060047	biological_process	heart contraction
E	0060052	biological_process	neurofilament cytoskeleton organization
E	0060087	biological_process	relaxation of vascular associated smooth muscle
E	0060088	biological_process	auditory receptor cell stereocilium organization
E	0070062	cellular_component	extracellular exosome
E	0072593	biological_process	reactive oxygen species metabolic process
E	0099610	biological_process	action potential initiation
E	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
E	1904115	cellular_component	axon cytoplasm
E	2000242	biological_process	negative regulation of reproductive process
F	0000302	biological_process	response to reactive oxygen species
F	0000303	biological_process	response to superoxide
F	0001541	biological_process	ovarian follicle development
F	0001819	biological_process	positive regulation of cytokine production
F	0001890	biological_process	placenta development
F	0001895	biological_process	retina homeostasis
F	0002262	biological_process	myeloid cell homeostasis
F	0004784	molecular_function	superoxide dismutase activity
F	0005507	molecular_function	copper ion binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005758	cellular_component	mitochondrial intermembrane space
F	0005759	cellular_component	mitochondrial matrix
F	0005777	cellular_component	peroxisome
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006749	biological_process	glutathione metabolic process
F	0006801	biological_process	superoxide metabolic process
F	0006879	biological_process	intracellular iron ion homeostasis
F	0006915	biological_process	apoptotic process
F	0006979	biological_process	response to oxidative stress
F	0007283	biological_process	spermatogenesis
F	0007566	biological_process	embryo implantation
F	0007605	biological_process	sensory perception of sound
F	0007626	biological_process	locomotory behavior
F	0008089	biological_process	anterograde axonal transport
F	0008090	biological_process	retrograde axonal transport
F	0008217	biological_process	regulation of blood pressure
F	0008270	molecular_function	zinc ion binding
F	0008340	biological_process	determination of adult lifespan
F	0009408	biological_process	response to heat
F	0009410	biological_process	response to xenobiotic stimulus
F	0010467	biological_process	gene expression
F	0016209	molecular_function	antioxidant activity
F	0016491	molecular_function	oxidoreductase activity
F	0019226	biological_process	transmission of nerve impulse
F	0019228	biological_process	neuronal action potential
F	0019430	biological_process	removal of superoxide radicals
F	0030346	molecular_function	protein phosphatase 2B binding
F	0031267	molecular_function	small GTPase binding
F	0031410	cellular_component	cytoplasmic vesicle
F	0032287	biological_process	peripheral nervous system myelin maintenance
F	0032839	cellular_component	dendrite cytoplasm
F	0032930	biological_process	positive regulation of superoxide anion generation
F	0032991	cellular_component	protein-containing complex
F	0033081	biological_process	regulation of T cell differentiation in thymus
F	0035234	biological_process	ectopic germ cell programmed cell death
F	0040014	biological_process	regulation of multicellular organism growth
F	0042542	biological_process	response to hydrogen peroxide
F	0042554	biological_process	superoxide anion generation
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0043025	cellular_component	neuronal cell body
F	0043065	biological_process	positive regulation of apoptotic process
F	0043066	biological_process	negative regulation of apoptotic process
F	0043087	biological_process	regulation of GTPase activity
F	0043410	biological_process	positive regulation of MAPK cascade
F	0043524	biological_process	negative regulation of neuron apoptotic process
F	0045471	biological_process	response to ethanol
F	0046620	biological_process	regulation of organ growth
F	0046716	biological_process	muscle cell cellular homeostasis
F	0046872	molecular_function	metal ion binding
F	0048538	biological_process	thymus development
F	0048678	biological_process	response to axon injury
F	0050665	biological_process	hydrogen peroxide biosynthetic process
F	0050728	biological_process	negative regulation of inflammatory response
F	0050766	biological_process	positive regulation of phagocytosis
F	0051087	molecular_function	protein-folding chaperone binding
F	0051093	biological_process	negative regulation of developmental process
F	0051881	biological_process	regulation of mitochondrial membrane potential
F	0060047	biological_process	heart contraction
F	0060052	biological_process	neurofilament cytoskeleton organization
F	0060087	biological_process	relaxation of vascular associated smooth muscle
F	0060088	biological_process	auditory receptor cell stereocilium organization
F	0070062	cellular_component	extracellular exosome
F	0072593	biological_process	reactive oxygen species metabolic process
F	0099610	biological_process	action potential initiation
F	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
F	1904115	cellular_component	axon cytoplasm
F	2000242	biological_process	negative regulation of reproductive process
I	0000302	biological_process	response to reactive oxygen species
I	0000303	biological_process	response to superoxide
I	0001541	biological_process	ovarian follicle development
I	0001819	biological_process	positive regulation of cytokine production
I	0001890	biological_process	placenta development
I	0001895	biological_process	retina homeostasis
I	0002262	biological_process	myeloid cell homeostasis
I	0004784	molecular_function	superoxide dismutase activity
I	0005507	molecular_function	copper ion binding
I	0005515	molecular_function	protein binding
I	0005576	cellular_component	extracellular region
I	0005615	cellular_component	extracellular space
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005758	cellular_component	mitochondrial intermembrane space
I	0005759	cellular_component	mitochondrial matrix
I	0005777	cellular_component	peroxisome
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0006749	biological_process	glutathione metabolic process
I	0006801	biological_process	superoxide metabolic process
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006915	biological_process	apoptotic process
I	0006979	biological_process	response to oxidative stress
I	0007283	biological_process	spermatogenesis
I	0007566	biological_process	embryo implantation
I	0007605	biological_process	sensory perception of sound
I	0007626	biological_process	locomotory behavior
I	0008089	biological_process	anterograde axonal transport
I	0008090	biological_process	retrograde axonal transport
I	0008217	biological_process	regulation of blood pressure
I	0008270	molecular_function	zinc ion binding
I	0008340	biological_process	determination of adult lifespan
I	0009408	biological_process	response to heat
I	0009410	biological_process	response to xenobiotic stimulus
I	0010467	biological_process	gene expression
I	0016209	molecular_function	antioxidant activity
I	0016491	molecular_function	oxidoreductase activity
I	0019226	biological_process	transmission of nerve impulse
I	0019228	biological_process	neuronal action potential
I	0019430	biological_process	removal of superoxide radicals
I	0030346	molecular_function	protein phosphatase 2B binding
I	0031267	molecular_function	small GTPase binding
I	0031410	cellular_component	cytoplasmic vesicle
I	0032287	biological_process	peripheral nervous system myelin maintenance
I	0032839	cellular_component	dendrite cytoplasm
I	0032930	biological_process	positive regulation of superoxide anion generation
I	0032991	cellular_component	protein-containing complex
I	0033081	biological_process	regulation of T cell differentiation in thymus
I	0035234	biological_process	ectopic germ cell programmed cell death
I	0040014	biological_process	regulation of multicellular organism growth
I	0042542	biological_process	response to hydrogen peroxide
I	0042554	biological_process	superoxide anion generation
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0043025	cellular_component	neuronal cell body
I	0043065	biological_process	positive regulation of apoptotic process
I	0043066	biological_process	negative regulation of apoptotic process
I	0043087	biological_process	regulation of GTPase activity
I	0043410	biological_process	positive regulation of MAPK cascade
I	0043524	biological_process	negative regulation of neuron apoptotic process
I	0045471	biological_process	response to ethanol
I	0046620	biological_process	regulation of organ growth
I	0046716	biological_process	muscle cell cellular homeostasis
I	0046872	molecular_function	metal ion binding
I	0048538	biological_process	thymus development
I	0048678	biological_process	response to axon injury
I	0050665	biological_process	hydrogen peroxide biosynthetic process
I	0050728	biological_process	negative regulation of inflammatory response
I	0050766	biological_process	positive regulation of phagocytosis
I	0051087	molecular_function	protein-folding chaperone binding
I	0051093	biological_process	negative regulation of developmental process
I	0051881	biological_process	regulation of mitochondrial membrane potential
I	0060047	biological_process	heart contraction
I	0060052	biological_process	neurofilament cytoskeleton organization
I	0060087	biological_process	relaxation of vascular associated smooth muscle
I	0060088	biological_process	auditory receptor cell stereocilium organization
I	0070062	cellular_component	extracellular exosome
I	0072593	biological_process	reactive oxygen species metabolic process
I	0099610	biological_process	action potential initiation
I	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
I	1904115	cellular_component	axon cytoplasm
I	2000242	biological_process	negative regulation of reproductive process
J	0000302	biological_process	response to reactive oxygen species
J	0000303	biological_process	response to superoxide
J	0001541	biological_process	ovarian follicle development
J	0001819	biological_process	positive regulation of cytokine production
J	0001890	biological_process	placenta development
J	0001895	biological_process	retina homeostasis
J	0002262	biological_process	myeloid cell homeostasis
J	0004784	molecular_function	superoxide dismutase activity
J	0005507	molecular_function	copper ion binding
J	0005515	molecular_function	protein binding
J	0005576	cellular_component	extracellular region
J	0005615	cellular_component	extracellular space
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005758	cellular_component	mitochondrial intermembrane space
J	0005759	cellular_component	mitochondrial matrix
J	0005777	cellular_component	peroxisome
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0006749	biological_process	glutathione metabolic process
J	0006801	biological_process	superoxide metabolic process
J	0006879	biological_process	intracellular iron ion homeostasis
J	0006915	biological_process	apoptotic process
J	0006979	biological_process	response to oxidative stress
J	0007283	biological_process	spermatogenesis
J	0007566	biological_process	embryo implantation
J	0007605	biological_process	sensory perception of sound
J	0007626	biological_process	locomotory behavior
J	0008089	biological_process	anterograde axonal transport
J	0008090	biological_process	retrograde axonal transport
J	0008217	biological_process	regulation of blood pressure
J	0008270	molecular_function	zinc ion binding
J	0008340	biological_process	determination of adult lifespan
J	0009408	biological_process	response to heat
J	0009410	biological_process	response to xenobiotic stimulus
J	0010467	biological_process	gene expression
J	0016209	molecular_function	antioxidant activity
J	0016491	molecular_function	oxidoreductase activity
J	0019226	biological_process	transmission of nerve impulse
J	0019228	biological_process	neuronal action potential
J	0019430	biological_process	removal of superoxide radicals
J	0030346	molecular_function	protein phosphatase 2B binding
J	0031267	molecular_function	small GTPase binding
J	0031410	cellular_component	cytoplasmic vesicle
J	0032287	biological_process	peripheral nervous system myelin maintenance
J	0032839	cellular_component	dendrite cytoplasm
J	0032930	biological_process	positive regulation of superoxide anion generation
J	0032991	cellular_component	protein-containing complex
J	0033081	biological_process	regulation of T cell differentiation in thymus
J	0035234	biological_process	ectopic germ cell programmed cell death
J	0040014	biological_process	regulation of multicellular organism growth
J	0042542	biological_process	response to hydrogen peroxide
J	0042554	biological_process	superoxide anion generation
J	0042802	molecular_function	identical protein binding
J	0042803	molecular_function	protein homodimerization activity
J	0043025	cellular_component	neuronal cell body
J	0043065	biological_process	positive regulation of apoptotic process
J	0043066	biological_process	negative regulation of apoptotic process
J	0043087	biological_process	regulation of GTPase activity
J	0043410	biological_process	positive regulation of MAPK cascade
J	0043524	biological_process	negative regulation of neuron apoptotic process
J	0045471	biological_process	response to ethanol
J	0046620	biological_process	regulation of organ growth
J	0046716	biological_process	muscle cell cellular homeostasis
J	0046872	molecular_function	metal ion binding
J	0048538	biological_process	thymus development
J	0048678	biological_process	response to axon injury
J	0050665	biological_process	hydrogen peroxide biosynthetic process
J	0050728	biological_process	negative regulation of inflammatory response
J	0050766	biological_process	positive regulation of phagocytosis
J	0051087	molecular_function	protein-folding chaperone binding
J	0051093	biological_process	negative regulation of developmental process
J	0051881	biological_process	regulation of mitochondrial membrane potential
J	0060047	biological_process	heart contraction
J	0060052	biological_process	neurofilament cytoskeleton organization
J	0060087	biological_process	relaxation of vascular associated smooth muscle
J	0060088	biological_process	auditory receptor cell stereocilium organization
J	0070062	cellular_component	extracellular exosome
J	0072593	biological_process	reactive oxygen species metabolic process
J	0099610	biological_process	action potential initiation
J	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
J	1904115	cellular_component	axon cytoplasm
J	2000242	biological_process	negative regulation of reproductive process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 201

Chain	Residue
A	HIS63
A	HIS71
A	HIS80
A	ASP83

---

site_id	AC2
Number of Residues	2
Details	binding site for residue LQN A 202

Chain	Residue
A	CYS111
B	LQN202

---

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 203

Chain	Residue
A	THR58
A	SER142
A	ARG143

---

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 A 204

Chain	Residue
A	GLU40
A	ASP90
A	LYS91
E	LYS122

---

site_id	AC5
Number of Residues	2
Details	binding site for residue SO4 A 205

Chain	Residue
A	ASN19
A	TRP32

---

site_id	AC6
Number of Residues	2
Details	binding site for residue SO4 A 206

Chain	Residue
A	GLY41
A	LEU42

---

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 A 207

Chain	Residue
A	THR58
A	GLY61
A	PRO62
A	ARG143
A	HOH304

---

site_id	AC8
Number of Residues	7
Details	binding site for residue SO4 A 208

Chain	Residue
A	GLY73
A	PRO74
A	LYS75
A	ASP76
A	LEU126
E	LYS128
E	HOH303

---

site_id	AC9
Number of Residues	5
Details	binding site for residue GOL A 209

Chain	Residue
A	ASP76
A	GLU77
A	GLU78
A	HOH342
J	LYS75

---

site_id	AD1
Number of Residues	4
Details	binding site for residue CL A 210

Chain	Residue
A	PRO62
A	HIS63
A	LYS136
A	HOH331

---

site_id	AD2
Number of Residues	2
Details	binding site for residue CL A 211

Chain	Residue
A	ASP125
A	HOH338

---

site_id	AD3
Number of Residues	4
Details	binding site for residue CL A 212

Chain	Residue
A	HIS48
A	HIS120
A	ARG143
A	HOH331

---

site_id	AD4
Number of Residues	5
Details	binding site for residue ZN B 201

Chain	Residue
B	HIS63
B	HIS71
B	HIS80
B	ASP83
B	LYS136

---

site_id	AD5
Number of Residues	4
Details	binding site for residue SO4 B 203

Chain	Residue
B	HIS48
B	HIS120
B	THR137
B	ARG143

---

site_id	AD6
Number of Residues	4
Details	binding site for residue SO4 B 204

Chain	Residue
B	THR58
B	SER142
B	ARG143
B	HOH321

---

site_id	AD7
Number of Residues	2
Details	binding site for residue DMS B 205

Chain	Residue
B	GLU77
B	GLU78

---

site_id	AD8
Number of Residues	3
Details	binding site for residue DMS B 206

Chain	Residue
B	GLY61
B	PRO62
B	ARG143

---

site_id	AD9
Number of Residues	4
Details	binding site for residue ZN E 201

Chain	Residue
E	HIS63
E	HIS71
E	HIS80
E	ASP83

---

site_id	AE1
Number of Residues	4
Details	binding site for residue SO4 E 203

Chain	Residue
A	LYS128
E	LYS75
E	HOH303
J	LYS128

---

site_id	AE2
Number of Residues	3
Details	binding site for residue SO4 E 204

Chain	Residue
E	GLU40
E	ASP90
E	LYS91

---

site_id	AE3
Number of Residues	8
Details	binding site for residue SO4 E 205

Chain	Residue
E	HIS48
E	HIS63
E	HIS120
E	THR137
E	GLY141
E	ARG143
E	DMS211
E	HOH332

---

site_id	AE4
Number of Residues	4
Details	binding site for residue SO4 E 206

Chain	Residue
E	GLY41
E	LEU42
E	NA208
E	NA209

---

site_id	AE5
Number of Residues	3
Details	binding site for residue SO4 E 207

Chain	Residue
E	THR58
E	SER142
E	ARG143

---

site_id	AE6
Number of Residues	3
Details	binding site for residue NA E 208

Chain	Residue
E	SO4206
E	CL213
E	HOH340

---

site_id	AE7
Number of Residues	2
Details	binding site for residue NA E 209

Chain	Residue
E	SO4206
E	HOH351

---

site_id	AE8
Number of Residues	5
Details	binding site for residue NA E 210

Chain	Residue
E	LEU42
E	THR88
J	ASP125
J	GLY129
J	HOH335

---

site_id	AE9
Number of Residues	4
Details	binding site for residue DMS E 211

Chain	Residue
E	PRO62
E	ARG143
E	SO4205
E	GLY61

---

site_id	AF1
Number of Residues	5
Details	binding site for residue CL E 212

Chain	Residue
E	ALA123
E	ASN139
E	HOH342
E	HOH344
E	HOH347

---

site_id	AF2
Number of Residues	3
Details	binding site for residue CL E 213

Chain	Residue
E	NA208
E	HOH312
E	HOH344

---

site_id	AF3
Number of Residues	4
Details	binding site for residue ZN F 201

Chain	Residue
F	HIS63
F	HIS71
F	HIS80
F	ASP83

---

site_id	AF4
Number of Residues	3
Details	binding site for residue SO4 F 203

Chain	Residue
F	THR58
F	SER142
F	ARG143

---

site_id	AF5
Number of Residues	4
Details	binding site for residue SO4 F 204

Chain	Residue
F	GLN15
F	GLY16
F	ILE17
F	LYS36

---

site_id	AF6
Number of Residues	2
Details	binding site for residue SO4 F 205

Chain	Residue
F	TRP32
F	HOH329

---

site_id	AF7
Number of Residues	3
Details	binding site for residue SO4 F 206

Chain	Residue
F	GLU40
F	ASP90
F	LYS91

---

site_id	AF8
Number of Residues	4
Details	binding site for residue SO4 F 207

Chain	Residue
F	THR58
F	GLY61
F	PRO62
F	ARG143

---

site_id	AF9
Number of Residues	3
Details	binding site for residue DMS F 208

Chain	Residue
F	VAL7
F	GLY147
F	VAL148

---

site_id	AG1
Number of Residues	2
Details	binding site for residue CL F 209

Chain	Residue
F	HOH331
F	HOH333

---

site_id	AG2
Number of Residues	5
Details	binding site for residue ZN I 201

Chain	Residue
I	HIS63
I	HIS71
I	HIS80
I	ASP83
I	LYS136

---

site_id	AG3
Number of Residues	5
Details	binding site for residue ZN I 202

Chain	Residue
I	HIS46
I	HIS48
I	HIS63
I	HIS120
I	SO4205

---

site_id	AG4
Number of Residues	4
Details	binding site for residue SO4 I 204

Chain	Residue
B	LYS75
B	LYS128
F	LYS128
I	LYS128

---

site_id	AG5
Number of Residues	8
Details	binding site for residue SO4 I 205

Chain	Residue
I	HIS48
I	HIS63
I	HIS120
I	THR137
I	GLY141
I	ARG143
I	ZN202
I	HOH320

---

site_id	AG6
Number of Residues	5
Details	binding site for residue SO4 I 206

Chain	Residue
B	GLY41
B	LEU42
B	HOH333
I	LYS91
I	HOH308

---

site_id	AG7
Number of Residues	3
Details	binding site for residue SO4 I 207

Chain	Residue
I	THR58
I	SER142
I	ARG143

---

site_id	AG8
Number of Residues	4
Details	binding site for residue ZN J 202

Chain	Residue
J	HIS63
J	HIS71
J	HIS80
J	ASP83

---

site_id	AG9
Number of Residues	3
Details	binding site for residue SO4 J 203

Chain	Residue
J	THR58
J	SER142
J	ARG143

---

site_id	AH1
Number of Residues	6
Details	binding site for residue SO4 J 204

Chain	Residue
J	HIS48
J	HIS63
J	HIS120
J	THR137
J	ARG143
J	HOH333

---

site_id	AH2
Number of Residues	3
Details	binding site for residue SO4 J 205

Chain	Residue
A	LYS122
J	ASP90
J	LYS91

---

site_id	AH3
Number of Residues	1
Details	binding site for residue SO4 J 206

Chain	Residue
J	TRP32

---

site_id	AH4
Number of Residues	2
Details	binding site for residue NA J 207

Chain	Residue
J	LEU42
J	HOH343

---

site_id	AH5
Number of Residues	3
Details	binding site for residue NA J 208

Chain	Residue
A	HOH337
A	HOH344
J	CL210

---

site_id	AH6
Number of Residues	3
Details	binding site for residue NA J 209

Chain	Residue
E	HOH352
J	CL211
J	HOH331

---

site_id	AH7
Number of Residues	2
Details	binding site for residue CL J 210

Chain	Residue
E	HOH352
J	NA208

---

site_id	AH8
Number of Residues	4
Details	binding site for residue CL J 211

Chain	Residue
J	ASP124
J	NA209
J	HOH314
J	HOH326

---

site_id	AH9
Number of Residues	4
Details	binding site for residue CL J 212

Chain	Residue
J	GLY73
J	PRO74
J	LYS75
J	HOH340

---

site_id	AI1
Number of Residues	18
Details	binding site for Di-peptide LQN B 202 and CYS B 111

Chain	Residue
A	LQN202
B	ALA1
B	THR2
B	GLN22
B	LYS23
B	GLU24
B	SER25
B	PHE64
B	SER105
B	LEU106
B	SER107
B	SER107
B	GLY108
B	ASP109
B	HIS110
B	ILE112
B	ILE113
B	ARG115

---

site_id	AI2
Number of Residues	16
Details	binding site for Di-peptide LQN E 202 and CYS E 111

Chain	Residue
E	PHE64
E	SER105
E	LEU106
E	SER107
E	GLY108
E	ASP109
E	HIS110
E	ILE112
E	ILE113
E	ARG115
E	HOH350
F	LQN202
F	HOH330
J	ALA1
J	THR2
J	SER25

---

site_id	AI3
Number of Residues	15
Details	binding site for Di-peptide LQN F 202 and CYS F 111

Chain	Residue
E	LQN202
F	PHE64
F	SER105
F	LEU106
F	SER107
F	GLY108
F	ASP109
F	HIS110
F	ILE112
F	ILE113
F	ARG115
F	HOH330
F	HOH332
I	ASP109
I	LQN203

---

site_id	AI4
Number of Residues	14
Details	binding site for Di-peptide LQN I 203 and CYS I 111

Chain	Residue
F	LQN202
I	PHE64
I	SER105
I	LEU106
I	SER107
I	GLY108
I	ASP109
I	HIS110
I	ILE112
I	ILE113
I	ARG115
I	HOH310
I	HOH313
J	LQN201

---

site_id	AI5
Number of Residues	15
Details	binding site for Di-peptide LQN J 201 and CYS J 111

Chain	Residue
E	ALA1
E	THR2
E	SER25
E	SER107
I	LQN203
J	PHE64
J	SER105
J	LEU106
J	SER107
J	GLY108
J	ASP109
J	HIS110
J	ILE112
J	ILE113
J	ARG115

---

Functional Information from PROSITE/UniProt

site_id	PS00087
Number of Residues	11
Details	SOD_CU_ZN_1 Copper/Zinc superoxide dismutase signature 1. GFHVHEfGDnT

Chain	Residue	Details
A	GLY44-THR54

---

site_id	PS00332
Number of Residues	12
Details	SOD_CU_ZN_2 Copper/Zinc superoxide dismutase signature 2. GNAGsRlACgvI

Chain	Residue	Details
A	GLY138-ILE149

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	BINDING: BINDING => ECO:0000269|PubMed:12963370, ECO:0000269|PubMed:17548825

Chain	Residue	Details
A	HIS46
F	HIS46
F	HIS48
F	HIS120
I	HIS46
I	HIS48
I	HIS120
J	HIS46
J	HIS48
J	HIS120
A	HIS48
A	HIS120
B	HIS46
B	HIS48
B	HIS120
E	HIS46
E	HIS48
E	HIS120

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269|PubMed:20727846

Chain	Residue	Details
A	HIS63
E	HIS71
E	HIS80
E	ASP83
F	HIS63
F	HIS71
F	HIS80
F	ASP83
I	HIS63
I	HIS71
I	HIS80
A	HIS71
I	ASP83
J	HIS63
J	HIS71
J	HIS80
J	ASP83
A	HIS80
A	ASP83
B	HIS63
B	HIS71
B	HIS80
B	ASP83
E	HIS63

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	MOD_RES: N-acetylalanine => ECO:0000269|PubMed:1463506, ECO:0000269|PubMed:7002610, ECO:0007744|PubMed:25944712

Chain	Residue	Details
A	ALA1
B	ALA1
E	ALA1
F	ALA1
I	ALA1
J	ALA1

---

site_id	SWS_FT_FI4
Number of Residues	18
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P08228

Chain	Residue	Details
A	LYS3
F	LYS3
F	LYS9
F	LYS91
I	LYS3
I	LYS9
I	LYS91
J	LYS3
J	LYS9
J	LYS91
A	LYS9
A	LYS91
B	LYS3
B	LYS9
B	LYS91
E	LYS3
E	LYS9
E	LYS91

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER98
B	SER98
E	SER98
F	SER98
I	SER98
J	SER98

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER102
B	SER102
E	SER102
F	SER102
I	SER102
J	SER102

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P07632

Chain	Residue	Details
A	SER105
B	SER105
E	SER105
F	SER105
I	SER105
J	SER105

---

site_id	SWS_FT_FI8
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P08228

Chain	Residue	Details
A	SER107
B	SER107
E	SER107
F	SER107
I	SER107
J	SER107

---

site_id	SWS_FT_FI9
Number of Residues	6
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:24140062

Chain	Residue	Details
A	LYS122
B	LYS122
E	LYS122
F	LYS122
I	LYS122
J	LYS122

---

site_id	SWS_FT_FI10
Number of Residues	6
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P08228

Chain	Residue	Details
A	LYS136
B	LYS136
E	LYS136
F	LYS136
I	LYS136
J	LYS136

---

site_id	SWS_FT_FI11
Number of Residues	6
Details	LIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:22496122

Chain	Residue	Details
A	CYS6
B	CYS6
E	CYS6
F	CYS6
I	CYS6
J	CYS6

---

site_id	SWS_FT_FI12
Number of Residues	12
Details	CROSSLNK: 1-(tryptophan-3-yl)-tryptophan (Trp-Trp) (interchain with W-33) => ECO:0000269|PubMed:20600836

Chain	Residue	Details
A	TRP32
J	TRP32
B	TRP32
E	TRP32
F	TRP32
I	TRP32

---