6SP4
KEAP1 IN COMPLEX WITH COMPOUND 23
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008134 | molecular_function | transcription factor binding |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
| B | 0008134 | molecular_function | transcription factor binding |
| B | 0016567 | biological_process | protein ubiquitination |
| B | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
| C | 0008134 | molecular_function | transcription factor binding |
| C | 0016567 | biological_process | protein ubiquitination |
| C | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
| D | 0008134 | molecular_function | transcription factor binding |
| D | 0016567 | biological_process | protein ubiquitination |
| D | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
| E | 0008134 | molecular_function | transcription factor binding |
| E | 0016567 | biological_process | protein ubiquitination |
| E | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
| F | 0008134 | molecular_function | transcription factor binding |
| F | 0016567 | biological_process | protein ubiquitination |
| F | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue LQK A 701 |
| Chain | Residue |
| A | TYR334 |
| A | TYR572 |
| A | PHE577 |
| A | SER602 |
| A | GLY603 |
| A | SER363 |
| A | GLY364 |
| A | LEU365 |
| A | ARG380 |
| A | ASN414 |
| A | ARG415 |
| A | ILE416 |
| A | ALA556 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue LQK B 701 |
| Chain | Residue |
| A | GLY386 |
| B | SER363 |
| B | GLY364 |
| B | LEU365 |
| B | ARG380 |
| B | ASN414 |
| B | ARG415 |
| B | GLY509 |
| B | ALA556 |
| B | LEU557 |
| B | TYR572 |
| B | SER602 |
| B | GLY603 |
| B | HOH809 |
| B | HOH811 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue LQK C 701 |
| Chain | Residue |
| C | TYR334 |
| C | SER363 |
| C | GLY364 |
| C | LEU365 |
| C | ARG380 |
| C | ASN414 |
| C | ARG415 |
| C | ALA556 |
| C | TYR572 |
| C | PHE577 |
| C | SER602 |
| C | GLY603 |
| C | HOH813 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue LQK D 701 |
| Chain | Residue |
| D | TYR334 |
| D | SER363 |
| D | GLY364 |
| D | LEU365 |
| D | ARG380 |
| D | ASN414 |
| D | ARG415 |
| D | GLY509 |
| D | ALA556 |
| D | SER602 |
| D | GLY603 |
| D | VAL604 |
| D | HOH810 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue LQK E 701 |
| Chain | Residue |
| E | TYR334 |
| E | SER363 |
| E | GLY364 |
| E | LEU365 |
| E | ASN414 |
| E | ARG415 |
| E | ALA556 |
| E | TYR572 |
| E | PHE577 |
| E | SER602 |
| E | VAL604 |
| E | HOH821 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue LQK F 701 |
| Chain | Residue |
| F | TYR334 |
| F | SER363 |
| F | GLY364 |
| F | LEU365 |
| F | ARG380 |
| F | ASN414 |
| F | ARG415 |
| F | ILE416 |
| F | GLY509 |
| F | ALA556 |
| F | PHE577 |
| F | SER602 |
| F | VAL604 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | SITE: Sensor for electrophilic agents => ECO:0000250|UniProtKB:Q9Z2X8 |
| Chain | Residue | Details |
| A | CYS434 | |
| B | CYS434 | |
| C | CYS434 | |
| D | CYS434 | |
| E | CYS434 | |
| F | CYS434 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | MOD_RES: S-cGMP-cysteine => ECO:0000250|UniProtKB:Q9Z2X8 |
| Chain | Residue | Details |
| A | CYS434 | |
| B | CYS434 | |
| C | CYS434 | |
| D | CYS434 | |
| E | CYS434 | |
| F | CYS434 |
