6SMP

AntDE:AntF (holo): type II PKS acyl-carrier protein in complex with its ketosynthase bound to the hexaketide

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
C	0006633	biological_process	fatty acid biosynthetic process
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
E	0016746	molecular_function	acyltransferase activity
E	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
F	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
F	0006633	biological_process	fatty acid biosynthetic process
F	0016746	molecular_function	acyltransferase activity
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
H	0016746	molecular_function	acyltransferase activity
H	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
I	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
I	0006633	biological_process	fatty acid biosynthetic process
I	0016746	molecular_function	acyltransferase activity
I	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
K	0016746	molecular_function	acyltransferase activity
K	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
L	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
L	0006633	biological_process	fatty acid biosynthetic process
L	0016746	molecular_function	acyltransferase activity
L	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue LLE A 501

Chain	Residue
A	SER38
B	THR284
B	ASP285
B	HIS317
B	SER319
B	THR321
B	GLN323
B	ASN324
B	HIS354
B	GLY412
B	PHE413
B	ILE116
C	ALA130
C	TRP133
C	PHE134
B	ALA119
B	GLY175
B	CYS176
B	LEU210
B	SER211
B	SER214
B	PHE215

---

site_id	AC2
Number of Residues	26
Details	binding site for Di-peptide LLE D 501 and SER D 38

Chain	Residue
D	ASP37
D	THR39
D	GLU40
D	LEU41
D	ALA42
E	ILE116
E	ALA119
E	GLY175
E	CYS176
E	LEU210
E	SER214
E	PHE215
E	THR284
E	ASP285
E	HIS317
E	SER319
E	THR321
E	GLN323
E	ASN324
E	HIS354
E	SER411
E	GLY412
E	PHE413
F	ALA130
F	TRP133
F	PHE134

---

site_id	AC3
Number of Residues	26
Details	binding site for Di-peptide LLE D 501 and CYS E 176

Chain	Residue
D	SER38
E	ILE116
E	ALA119
E	THR174
E	GLY175
E	ALA177
E	ALA178
E	LEU210
E	SER214
E	PHE215
E	THR284
E	ASP285
E	HIS317
E	SER319
E	THR321
E	GLN323
E	ASN324
E	HIS354
E	LEU356
E	ASN360
E	SER411
E	GLY412
E	PHE413
F	ALA130
F	TRP133
F	PHE134

---

site_id	AC4
Number of Residues	25
Details	binding site for Di-peptide LLE G 501 and CYS H 176

Chain	Residue
G	SER38
H	ILE116
H	ALA119
H	THR174
H	GLY175
H	ALA177
H	ALA178
H	LEU210
H	SER214
H	PHE215
H	GLY219
H	THR284
H	ASP285
H	SER319
H	THR321
H	GLN323
H	ASN324
H	HIS354
H	ASN360
H	SER411
H	GLY412
H	PHE413
I	ALA130
I	TRP133
I	PHE134

---

site_id	AC5
Number of Residues	26
Details	binding site for Di-peptide LLE G 501 and SER G 38

Chain	Residue
G	ASP37
G	THR39
G	GLU40
G	LEU41
G	ALA42
H	ILE116
H	ALA119
H	GLY175
H	CYS176
H	LEU210
H	SER214
H	PHE215
H	GLY219
H	THR284
H	ASP285
H	SER319
H	THR321
H	GLN323
H	ASN324
H	HIS354
H	SER411
H	GLY412
H	PHE413
I	ALA130
I	TRP133
I	PHE134

---

site_id	AC6
Number of Residues	26
Details	binding site for Di-peptide LLE J 501 and CYS K 176

Chain	Residue
J	SER38
K	ILE116
K	THR174
K	GLY175
K	ALA177
K	ALA178
K	LEU210
K	SER214
K	PHE215
K	THR284
K	ASP285
K	HIS317
K	SER319
K	THR321
K	GLN323
K	ASN324
K	HIS354
K	ASN360
K	SER411
K	GLY412
K	PHE413
L	ILE110
L	VAL129
L	ALA130
L	TRP133
L	PHE134

---

site_id	AC7
Number of Residues	26
Details	binding site for Di-peptide LLE J 501 and SER J 38

Chain	Residue
J	ASP37
J	THR39
J	GLU40
J	LEU41
J	ALA42
K	ILE116
K	GLY175
K	CYS176
K	LEU210
K	SER214
K	PHE215
K	THR284
K	ASP285
K	HIS317
K	SER319
K	THR321
K	GLN323
K	ASN324
K	HIS354
K	GLY412
K	PHE413
L	ILE110
L	VAL129
L	ALA130
L	TRP133
L	PHE134

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