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6SLE

Structure of Reductive Aminase from Neosartorya fumigata in complex with NADP+

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0000785cellular_componentchromatin
A0003677molecular_functionDNA binding
A0008442molecular_function3-hydroxyisobutyrate dehydrogenase activity
A0016491molecular_functionoxidoreductase activity
A0031491molecular_functionnucleosome binding
A0050661molecular_functionNADP binding
A0140673biological_processtranscription elongation-coupled chromatin remodeling
B0000166molecular_functionnucleotide binding
B0000785cellular_componentchromatin
B0003677molecular_functionDNA binding
B0008442molecular_function3-hydroxyisobutyrate dehydrogenase activity
B0016491molecular_functionoxidoreductase activity
B0031491molecular_functionnucleosome binding
B0050661molecular_functionNADP binding
B0140673biological_processtranscription elongation-coupled chromatin remodeling
C0000166molecular_functionnucleotide binding
C0000785cellular_componentchromatin
C0003677molecular_functionDNA binding
C0008442molecular_function3-hydroxyisobutyrate dehydrogenase activity
C0016491molecular_functionoxidoreductase activity
C0031491molecular_functionnucleosome binding
C0050661molecular_functionNADP binding
C0140673biological_processtranscription elongation-coupled chromatin remodeling
D0000166molecular_functionnucleotide binding
D0000785cellular_componentchromatin
D0003677molecular_functionDNA binding
D0008442molecular_function3-hydroxyisobutyrate dehydrogenase activity
D0016491molecular_functionoxidoreductase activity
D0031491molecular_functionnucleosome binding
D0050661molecular_functionNADP binding
D0140673biological_processtranscription elongation-coupled chromatin remodeling
E0000166molecular_functionnucleotide binding
E0000785cellular_componentchromatin
E0003677molecular_functionDNA binding
E0008442molecular_function3-hydroxyisobutyrate dehydrogenase activity
E0016491molecular_functionoxidoreductase activity
E0031491molecular_functionnucleosome binding
E0050661molecular_functionNADP binding
E0140673biological_processtranscription elongation-coupled chromatin remodeling
F0000166molecular_functionnucleotide binding
F0000785cellular_componentchromatin
F0003677molecular_functionDNA binding
F0008442molecular_function3-hydroxyisobutyrate dehydrogenase activity
F0016491molecular_functionoxidoreductase activity
F0031491molecular_functionnucleosome binding
F0050661molecular_functionNADP binding
F0140673biological_processtranscription elongation-coupled chromatin remodeling
G0000166molecular_functionnucleotide binding
G0000785cellular_componentchromatin
G0003677molecular_functionDNA binding
G0008442molecular_function3-hydroxyisobutyrate dehydrogenase activity
G0016491molecular_functionoxidoreductase activity
G0031491molecular_functionnucleosome binding
G0050661molecular_functionNADP binding
G0140673biological_processtranscription elongation-coupled chromatin remodeling
H0000166molecular_functionnucleotide binding
H0000785cellular_componentchromatin
H0003677molecular_functionDNA binding
H0008442molecular_function3-hydroxyisobutyrate dehydrogenase activity
H0016491molecular_functionoxidoreductase activity
H0031491molecular_functionnucleosome binding
H0050661molecular_functionNADP binding
H0140673biological_processtranscription elongation-coupled chromatin remodeling
Functional Information from PDB Data
site_idAC1
Number of Residues24
Detailsbinding site for residue NAP A 1000
ChainResidue
AGLY8
ALEU65
ALEU66
AALA70
ATHR74
ATHR91
AASN92
AILE117
AALA119
APRO121
AHOH1103
ALEU9
AHOH1104
BSER229
BASN230
BMET233
CALA267
AGLY10
AALA11
AMET12
AASN31
AARG32
ASER33
ACYS64

site_idAC2
Number of Residues16
Detailsbinding site for residue NAP B 301
ChainResidue
ASER229
AASN230
AMET233
BLEU9
BGLY10
BALA11
BMET12
BARG32
BSER33
BLEU65
BLEU66
BASN92
BILE117
BALA119
BTHR120
BPRO121

site_idAC3
Number of Residues19
Detailsbinding site for residue NAP C 301
ChainResidue
CGLY8
CLEU9
CGLY10
CALA11
CMET12
CASN31
CARG32
CSER33
CCYS64
CLEU65
CLEU66
CALA70
CTHR91
CASN92
CILE117
CALA119
HSER229
HASN230
HMET233

site_idAC4
Number of Residues22
Detailsbinding site for residue NAP D 301
ChainResidue
DLEU9
DGLY10
DALA11
DMET12
DASN31
DARG32
DSER33
DALA37
DCYS64
DLEU65
DLEU66
DALA70
DTHR74
DTHR91
DASN92
DILE117
DALA119
DHOH408
ESER229
EASN230
EMET233
GALA267

site_idAC5
Number of Residues17
Detailsbinding site for residue NAP E 301
ChainResidue
DSER229
DASN230
DMET233
EGLY8
ELEU9
EGLY10
EALA11
EMET12
EARG32
ECYS64
ELEU65
ELEU66
EALA70
EASN92
EILE117
EALA119
EHOH405

site_idAC6
Number of Residues21
Detailsbinding site for residue NAP F 301
ChainResidue
FGLY8
FLEU9
FGLY10
FALA11
FMET12
FASN31
FARG32
FSER33
FCYS64
FLEU65
FLEU66
FALA70
FTHR74
FASN92
FILE117
FALA119
FPRO121
GSER229
GASN230
GMET233
EALA267

site_idAC7
Number of Residues19
Detailsbinding site for residue NAP G 301
ChainResidue
FSER229
FASN230
FMET233
GLEU9
GGLY10
GALA11
GMET12
GASN31
GSER33
GCYS64
GLEU65
GLEU66
GTHR91
GASN92
GILE117
GALA119
GPRO121
GHOH401
GHOH408

site_idAC8
Number of Residues20
Detailsbinding site for residue NAP H 1001
ChainResidue
BALA267
CSER229
CASN230
CMET233
HLEU9
HGLY10
HALA11
HMET12
HASN31
HARG32
HSER33
HCYS64
HLEU65
HLEU66
HALA70
HTHR74
HTHR91
HASN92
HILE117
HALA119

239149

PDB entries from 2025-07-23

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