Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004089 | molecular_function | carbonate dehydratase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0015670 | biological_process | carbon dioxide transport |
| A | 0016829 | molecular_function | lyase activity |
| A | 0018820 | molecular_function | cyanamide hydratase activity |
| A | 0038166 | biological_process | angiotensin-activated signaling pathway |
| A | 0044070 | biological_process | regulation of monoatomic anion transport |
| A | 0045177 | cellular_component | apical part of cell |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051453 | biological_process | regulation of intracellular pH |
| A | 2001150 | biological_process | positive regulation of dipeptide transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CU A 301 |
| Chain | Residue |
| A | HIS2 |
| A | HIS9 |
| A | HIS14 |
| A | ASP18 |
| A | HOH571 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CU A 302 |
| Chain | Residue |
| A | ASP150 |
| A | E68308 |
| A | HOH538 |
| A | HOH548 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CU A 303 |
| Chain | Residue |
| A | HIS3 |
| A | TRP4 |
| A | HIS63 |
| A | HOH401 |
| A | HOH575 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CU A 304 |
| Chain | Residue |
| A | HIS3 |
| A | HIS63 |
| A | HOH553 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 305 |
| Chain | Residue |
| A | HIS93 |
| A | HIS95 |
| A | HIS118 |
| A | E68308 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 306 |
| Chain | Residue |
| A | TYR6 |
| A | TRP243 |
| A | HOH433 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 307 |
| Chain | Residue |
| A | ASN61 |
| A | HIS63 |
| A | SER64 |
| A | ASN66 |
| A | GLN91 |
| A | HIS93 |
| A | E68308 |
| A | HOH424 |
| A | HOH503 |
| A | HOH506 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | binding site for residue E68 A 308 |
| Chain | Residue |
| A | ASP71 |
| A | VAL90 |
| A | GLN91 |
| A | HIS93 |
| A | HIS95 |
| A | HIS118 |
| A | VAL120 |
| A | PHE129 |
| A | ASP150 |
| A | LEU196 |
| A | THR197 |
| A | THR198 |
| A | TRP207 |
| A | CU302 |
| A | ZN305 |
| A | GOL307 |
| A | HOH410 |
| A | HOH549 |
Functional Information from PROSITE/UniProt
| site_id | PS00162 |
| Number of Residues | 17 |
| Details | ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHtVdrkkYaaELHLV |
| Chain | Residue | Details |
| A | SER104-VAL120 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS63 | |
| Chain | Residue | Details |
| A | HIS93 | |
| A | HIS95 | |
| A | HIS118 | |
| Chain | Residue | Details |
| A | THR197 | |
| Chain | Residue | Details |
| A | TYR6 | |
| A | ASN61 | |
| A | ASN66 | |
| Chain | Residue | Details |
| A | SER164 | |
| A | SER171 | |
