Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue LH5 A 301 |
| Chain | Residue |
| A | LEU41 |
| A | VAL213 |
| A | TRP215 |
| A | GLY216 |
| A | ASP217 |
| A | TYR218 |
| A | CYS220 |
| A | GLY226 |
| A | RH5302 |
| A | HOH459 |
| A | HOH471 |
| A | HIS57 |
| A | ASP189 |
| A | SER190 |
| A | CYS191 |
| A | GLN192 |
| A | GLY193 |
| A | ASP194 |
| A | SER195 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue RH5 A 302 |
| Chain | Residue |
| A | LEU41 |
| A | HIS57 |
| A | ASP189 |
| A | SER190 |
| A | CYS191 |
| A | GLN192 |
| A | GLY193 |
| A | ASP194 |
| A | SER195 |
| A | GLY216 |
| A | ASP217 |
| A | TYR218 |
| A | CYS220 |
| A | LH5301 |
| A | HOH471 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 303 |
| Chain | Residue |
| A | PRO92 |
| A | ASP93 |
| C | TYR34 |
| C | PHE66 |
| C | LYS70 |
| C | LEU73 |
| C | HOH449 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | binding site for residue LH5 C 302 |
| Chain | Residue |
| A | GLY38 |
| C | LEU41 |
| C | HIS57 |
| C | ASP189 |
| C | SER190 |
| C | CYS191 |
| C | GLN192 |
| C | GLY193 |
| C | ASP194 |
| C | SER195 |
| C | VAL213 |
| C | TRP215 |
| C | GLY216 |
| C | ASP217 |
| C | TYR218 |
| C | CYS220 |
| C | RH5301 |
| C | HOH459 |
| C | HOH487 |
| C | HOH505 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide LH5 B 301 and SER B 195 |
| Chain | Residue |
| B | LEU41 |
| B | CYS42 |
| B | GLY43 |
| B | HIS57 |
| B | ASP189 |
| B | SER190 |
| B | CYS191 |
| B | GLY193 |
| B | ASP194 |
| B | GLY196 |
| B | GLY197 |
| B | VAL213 |
| B | TRP215 |
| B | GLY216 |
| B | ASP217 |
| B | TYR218 |
| B | CYS220 |
| B | RH5302 |
| B | HOH422 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide RH5 B 302 and SER B 195 |
| Chain | Residue |
| B | LEU41 |
| B | CYS42 |
| B | GLY43 |
| B | HIS57 |
| B | ASP189 |
| B | SER190 |
| B | CYS191 |
| B | GLY193 |
| B | ASP194 |
| B | GLY196 |
| B | GLY197 |
| B | VAL213 |
| B | TRP215 |
| B | GLY216 |
| B | ASP217 |
| B | TYR218 |
| B | CYS220 |
| B | LH5301 |
| site_id | AC7 |
| Number of Residues | 21 |
| Details | binding site for Di-peptide RH5 C 301 and SER C 195 |
| Chain | Residue |
| C | LEU41 |
| C | CYS42 |
| C | GLY43 |
| C | HIS57 |
| C | CYS58 |
| C | ASP189 |
| C | SER190 |
| C | CYS191 |
| C | GLN192 |
| C | GLY193 |
| C | ASP194 |
| C | GLY196 |
| C | GLY197 |
| C | VAL213 |
| C | GLY216 |
| C | ASP217 |
| C | TYR218 |
| C | CYS220 |
| C | LH5302 |
| C | HOH505 |
| A | GLY38 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| B | HIS57 | |
| B | ASP102 | |
| B | SER195 | |
| C | HIS57 | |
| C | ASP102 | |
| C | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by autolysis |
| Chain | Residue | Details |
| A | GLN76 | |
| B | GLN76 | |
| C | GLN76 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN132 | |
| B | GLN132 | |
| C | GLN132 | |
