6SJS
Methyltransferase of the MtgA N227A mutant from Desulfitobacterium hafniense in complex with methyl-tetrahydrofolate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0030269 | molecular_function | tetrahydromethanopterin S-methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0044237 | biological_process | cellular metabolic process |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0030269 | molecular_function | tetrahydromethanopterin S-methyltransferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0044237 | biological_process | cellular metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue THH A 901 |
| Chain | Residue |
| A | SER32 |
| A | TYR230 |
| A | LEU263 |
| A | PRO266 |
| A | HOH1008 |
| A | HOH1040 |
| A | HOH1052 |
| A | TYR35 |
| A | ASP75 |
| A | ASP102 |
| A | ASN129 |
| A | VAL152 |
| A | ASP194 |
| A | ALA224 |
| A | SER226 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 902 |
| Chain | Residue |
| A | GLY19 |
| A | TYR25 |
| A | ASP260 |
| A | HOH1022 |
| A | HOH1031 |
| A | HOH1035 |
| A | HOH1042 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue THH B 901 |
| Chain | Residue |
| B | ASN129 |
| B | VAL152 |
| B | LEU154 |
| B | ASP194 |
| B | HOH1003 |
| B | HOH1022 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 902 |
| Chain | Residue |
| B | LEU57 |
| B | GLN60 |
| B | GLU61 |
| B | MET267 |
| B | ALA270 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 903 |
| Chain | Residue |
| A | ARG185 |
| B | LYS39 |
| B | ILE40 |
| B | ASP50 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 904 |
| Chain | Residue |
| B | ASP12 |
| B | ILE13 |
| B | ASN14 |
| B | GLN123 |
| B | LYS124 |
| B | LYS149 |
| B | THR150 |
| B | GLN190 |
| B | HOH1019 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 905 |
| Chain | Residue |
| B | TYR135 |
| B | GLU137 |
| B | GOL907 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 906 |
| Chain | Residue |
| A | PHE49 |
| A | ASP50 |
| A | LYS51 |
| A | ASP52 |
| B | LYS3 |
| B | THR5 |
| B | GLN7 |
| B | GLN21 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 907 |
| Chain | Residue |
| A | LYS114 |
| A | GLU145 |
| B | THR136 |
| B | GLU137 |
| B | GLU138 |
| B | GOL905 |
