6SJB

Cryo-EM structure of the RecBCD Chi recognised complex

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000287	molecular_function	magnesium ion binding
B	0000724	biological_process	double-strand break repair via homologous recombination
B	0000725	biological_process	recombinational repair
B	0003677	molecular_function	DNA binding
B	0003678	molecular_function	DNA helicase activity
B	0003689	molecular_function	DNA clamp loader activity
B	0004386	molecular_function	helicase activity
B	0004520	molecular_function	DNA endonuclease activity
B	0004527	molecular_function	exonuclease activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006281	biological_process	DNA repair
B	0006310	biological_process	DNA recombination
B	0006338	biological_process	chromatin remodeling
B	0008094	molecular_function	ATP-dependent activity, acting on DNA
B	0008854	molecular_function	exodeoxyribonuclease V activity
B	0009314	biological_process	response to radiation
B	0009338	cellular_component	exodeoxyribonuclease V complex
B	0015616	molecular_function	DNA translocase activity
B	0016787	molecular_function	hydrolase activity
B	0016853	molecular_function	isomerase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0032508	biological_process	DNA duplex unwinding
B	0043138	molecular_function	3'-5' DNA helicase activity
B	0044355	biological_process	clearance of foreign intracellular DNA
B	0046872	molecular_function	metal ion binding
B	0061775	molecular_function	cohesin loader activity
B	0140584	molecular_function	chromatin extrusion motor activity
B	0140588	biological_process	chromatin looping
B	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
B	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
C	0000724	biological_process	double-strand break repair via homologous recombination
C	0000725	biological_process	recombinational repair
C	0003677	molecular_function	DNA binding
C	0003678	molecular_function	DNA helicase activity
C	0004386	molecular_function	helicase activity
C	0004527	molecular_function	exonuclease activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0008854	molecular_function	exodeoxyribonuclease V activity
C	0009314	biological_process	response to radiation
C	0009338	cellular_component	exodeoxyribonuclease V complex
C	0032508	biological_process	DNA duplex unwinding
C	0044355	biological_process	clearance of foreign intracellular DNA
C	0140097	molecular_function	catalytic activity, acting on DNA
D	0000724	biological_process	double-strand break repair via homologous recombination
D	0000725	biological_process	recombinational repair
D	0003677	molecular_function	DNA binding
D	0003689	molecular_function	DNA clamp loader activity
D	0004386	molecular_function	helicase activity
D	0004527	molecular_function	exonuclease activity
D	0005524	molecular_function	ATP binding
D	0006281	biological_process	DNA repair
D	0006302	biological_process	double-strand break repair
D	0006310	biological_process	DNA recombination
D	0006338	biological_process	chromatin remodeling
D	0006974	biological_process	DNA damage response
D	0008854	molecular_function	exodeoxyribonuclease V activity
D	0009338	cellular_component	exodeoxyribonuclease V complex
D	0016853	molecular_function	isomerase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0017116	molecular_function	single-stranded DNA helicase activity
D	0032508	biological_process	DNA duplex unwinding
D	0043139	molecular_function	5'-3' DNA helicase activity
D	0061775	molecular_function	cohesin loader activity
D	0140584	molecular_function	chromatin extrusion motor activity
D	0140588	biological_process	chromatin looping
D	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
D	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	DNA_BIND:

Chain	Residue	Details
B	ILE252-ARG254
B	VAL511-GLY512
B	SER560-ARG561
B	ARG761

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: For nuclease activity => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000269|PubMed:10518611, ECO:0000269|PubMed:9790841

Chain	Residue	Details
B	ALA1080

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000269|PubMed:15538360

Chain	Residue	Details
B	ALA23

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:15538360

Chain	Residue	Details
B	TRP447

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site_id	SWS_FT_FI5
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000305|PubMed:15538360, ECO:0000305|PubMed:18668125

Chain	Residue	Details
B	HIS956
B	ASP1067
B	ALA1080

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site_id	SWS_FT_FI6
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:15538360, ECO:0000305|PubMed:18668125

Chain	Residue	Details
B	TYR1081

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