Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 501 |
| Chain | Residue |
| A | CYS248 |
| A | HIS254 |
| A | CYS308 |
| A | CYS310 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue 3HA A 502 |
| Chain | Residue |
| A | SER238 |
| A | THR239 |
| A | ANP503 |
| A | THR135 |
| A | LEU138 |
| A | ALA211 |
| A | GLU235 |
| A | GLY237 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue ANP A 503 |
| Chain | Residue |
| A | LYS62 |
| A | ARG66 |
| A | SER88 |
| A | ALA212 |
| A | GLU213 |
| A | PRO214 |
| A | GLU234 |
| A | GLU235 |
| A | TYR236 |
| A | GLY237 |
| A | SER238 |
| A | THR239 |
| A | GLU240 |
| A | LEU297 |
| A | ASP299 |
| A | VAL319 |
| A | 3HA502 |
| A | MG510 |
| A | HOH620 |
| A | HOH672 |
| B | LYS418 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | ARG222 |
| A | ILE226 |
| A | ALA348 |
| A | GLU351 |
| A | VAL352 |
| A | EDO507 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | PRO161 |
| A | ARG164 |
| A | GLN413 |
| A | ARG414 |
| A | HOH624 |
| B | ALA91 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | LYS192 |
| A | ARG197 |
| A | PRO198 |
| A | ASP199 |
| A | ILE226 |
| A | HOH631 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | ARG222 |
| A | VAL343 |
| A | PHE344 |
| A | LEU346 |
| A | PRO347 |
| A | ALA348 |
| A | TYR350 |
| A | GLU351 |
| A | VAL352 |
| A | EDO504 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 508 |
| Chain | Residue |
| A | ARG78 |
| A | GLU79 |
| A | LEU81 |
| B | PRO120 |
| B | GLY147 |
| B | ALA148 |
| B | THR149 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 509 |
| Chain | Residue |
| A | PRO120 |
| A | GLY147 |
| A | ALA148 |
| A | THR149 |
| B | ARG78 |
| B | GLU79 |
| B | LEU81 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 510 |
| Chain | Residue |
| A | SER87 |
| A | GLU240 |
| A | ANP503 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 501 |
| Chain | Residue |
| B | CYS248 |
| B | HIS254 |
| B | CYS308 |
| B | CYS310 |
| site_id | AD3 |
| Number of Residues | 10 |
| Details | binding site for residue 3HA B 502 |
| Chain | Residue |
| A | HOH602 |
| B | THR135 |
| B | LEU138 |
| B | ALA211 |
| B | GLU235 |
| B | GLY237 |
| B | SER238 |
| B | THR239 |
| B | ANP503 |
| B | HOH647 |
| site_id | AD4 |
| Number of Residues | 23 |
| Details | binding site for residue ANP B 503 |
| Chain | Residue |
| B | GLU234 |
| B | GLU235 |
| B | TYR236 |
| B | GLY237 |
| B | SER238 |
| B | THR239 |
| B | GLU240 |
| B | ASP299 |
| B | VAL319 |
| B | ARG322 |
| B | 3HA502 |
| B | HOH605 |
| B | HOH623 |
| B | HOH647 |
| B | HOH668 |
| B | HOH696 |
| A | LYS418 |
| B | LYS62 |
| B | ARG66 |
| B | SER88 |
| B | ALA212 |
| B | GLU213 |
| B | PRO214 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| A | ARG78 |
| B | SER121 |
| B | ASP122 |
| B | THR123 |
| B | ASP173 |
| B | THR175 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | GLN21 |
| B | ALA257 |
| B | ILE261 |
| B | PHE262 |
| B | PRO315 |
| B | HOH601 |
| site_id | AD7 |
| Number of Residues | 10 |
| Details | binding site for residue PEG B 507 |
| Chain | Residue |
| B | ARG127 |
| B | THR128 |
| B | PRO129 |
| B | THR135 |
| B | CYS179 |
| B | ASN180 |
| B | GLU183 |
| B | ALA212 |
| B | HOH658 |
| B | HOH702 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 508 |
| Chain | Residue |
| B | ILE261 |
| B | GLU263 |
| B | VAL281 |
| B | VAL282 |
| B | THR283 |
