Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue ANP A 501 |
| Chain | Residue |
| A | LYS62 |
| A | GLY237 |
| A | SER238 |
| A | THR239 |
| A | GLU240 |
| A | ASP299 |
| A | VAL319 |
| A | HOH615 |
| A | HOH622 |
| A | HOH666 |
| A | HOH691 |
| A | SER87 |
| B | LYS418 |
| A | SER88 |
| A | ALA212 |
| A | GLU213 |
| A | PRO214 |
| A | GLU234 |
| A | GLU235 |
| A | TYR236 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 502 |
| Chain | Residue |
| A | CYS248 |
| A | HIS254 |
| A | CYS308 |
| A | CYS310 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 503 |
| Chain | Residue |
| A | PRO120 |
| A | GLY147 |
| A | ALA148 |
| A | THR149 |
| B | ARG78 |
| B | GLU79 |
| B | LEU81 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue FLC A 504 |
| Chain | Residue |
| A | ASP199 |
| A | GLN200 |
| A | GLN200 |
| A | GLY228 |
| A | HOH669 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | GLU7 |
| A | GLU109 |
| A | ARG113 |
| A | ARG259 |
| A | HOH617 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | GLU351 |
| A | PHE354 |
| A | GLU369 |
| A | PRO371 |
| A | HOH706 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 507 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 508 |
| Chain | Residue |
| A | ARG78 |
| A | GLU79 |
| A | LEU81 |
| B | PRO120 |
| B | GLY147 |
| B | THR149 |
| site_id | AC9 |
| Number of Residues | 22 |
| Details | binding site for residue ANP B 501 |
| Chain | Residue |
| A | LYS418 |
| B | LYS62 |
| B | SER87 |
| B | SER88 |
| B | ALA212 |
| B | GLU213 |
| B | PRO214 |
| B | GLU234 |
| B | GLU235 |
| B | TYR236 |
| B | GLY237 |
| B | SER238 |
| B | THR239 |
| B | GLU240 |
| B | ASP299 |
| B | VAL319 |
| B | ARG322 |
| B | HOH603 |
| B | HOH634 |
| B | HOH714 |
| B | HOH737 |
| B | HOH744 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 502 |
| Chain | Residue |
| B | CYS248 |
| B | HIS254 |
| B | CYS308 |
| B | CYS310 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | GLN21 |
| B | ALA257 |
| B | ILE261 |
| B | PHE262 |
| B | PRO315 |
| B | HOH619 |
| B | HOH688 |
