6SIT
Pseudo-atomic crystal structure of the desmoglein 2 - human adenovirus serotype 3 fibre knob complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007155 | biological_process | cell adhesion |
| A | 0019028 | cellular_component | viral capsid |
| A | 0019058 | biological_process | viral life cycle |
| A | 0019062 | biological_process | virion attachment to host cell |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0007155 | biological_process | cell adhesion |
| D | 0007156 | biological_process | homophilic cell-cell adhesion |
| D | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 401 |
| Chain | Residue |
| D | ASN104 |
| D | ASN106 |
| D | ASP136 |
| D | ASP138 |
| D | ASN144 |
| D | ASP194 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 402 |
| Chain | Residue |
| D | ASP215 |
| D | VAL216 |
| D | ASP218 |
| D | GLU121 |
| D | ARG180 |
| D | GLU181 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CA D 403 |
| Chain | Residue |
| D | GLU121 |
| D | ASP179 |
| D | GLU181 |
| D | ASP218 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 404 |
| Chain | Residue |
| D | ASN217 |
| D | ASN219 |
| D | ASP248 |
| D | ASP250 |
| D | ASN256 |
| D | ASN307 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA D 405 |
| Chain | Residue |
| D | GLU234 |
| D | GLU294 |
| D | ASN332 |
| D | VAL333 |
| D | GLU335 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CA D 406 |
| Chain | Residue |
| D | GLU234 |
| D | ASP292 |
| D | GLU294 |
| D | GLU335 |
Functional Information from PROSITE/UniProt
| site_id | PS00232 |
| Number of Residues | 11 |
| Details | CADHERIN_1 Cadherin domain signature. IrIlDvNDNiP |
| Chain | Residue | Details |
| D | ILE211-PRO221 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 112 |
| Details | Domain: {"description":"Cadherin 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00043","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
