6SHK

High resolution structure of the antimicrobial peptide Dermcidin from human

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008233	molecular_function	peptidase activity
A	0031640	biological_process	killing of cells of another organism

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 101

Chain	Residue
A	GLU5
A	ASP9
A	HIS38
A	ASP42

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 102

Chain	Residue
A	SER1
A	LYS20
A	ASP24
A	ASP28

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	44
Details	TRANSMEM: Helical => ECO:0000305|PubMed:23426625

Chain	Residue	Details
A	SER2-SER46

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: in chain A => ECO:0000269|PubMed:23426625, ECO:0007744|PDB:2YMK

Chain	Residue	Details
A	GLU5
A	ASP9

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:23426625, ECO:0007744|PDB:2YMK

Chain	Residue	Details
A	ASP24
A	ASP28

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site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: in chain B => ECO:0000269|PubMed:23426625, ECO:0007744|PDB:2YMK

Chain	Residue	Details
A	HIS38
A	ASP42

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS6

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