Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6SH4

Structure of the Apo1 state of the heptameric Bcs1 AAA-ATPase.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005829	cellular_component	cytosol
A	0008320	molecular_function	protein transmembrane transporter activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
A	0034551	biological_process	mitochondrial respiratory chain complex III assembly
A	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
A	0051131	biological_process	chaperone-mediated protein complex assembly
A	0055085	biological_process	transmembrane transport
A	0071806	biological_process	protein transmembrane transport
B	0005524	molecular_function	ATP binding
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005758	cellular_component	mitochondrial intermembrane space
B	0005829	cellular_component	cytosol
B	0008320	molecular_function	protein transmembrane transporter activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
B	0034551	biological_process	mitochondrial respiratory chain complex III assembly
B	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
B	0051131	biological_process	chaperone-mediated protein complex assembly
B	0055085	biological_process	transmembrane transport
B	0071806	biological_process	protein transmembrane transport
C	0005524	molecular_function	ATP binding
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005758	cellular_component	mitochondrial intermembrane space
C	0005829	cellular_component	cytosol
C	0008320	molecular_function	protein transmembrane transporter activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
C	0034551	biological_process	mitochondrial respiratory chain complex III assembly
C	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
C	0051131	biological_process	chaperone-mediated protein complex assembly
C	0055085	biological_process	transmembrane transport
C	0071806	biological_process	protein transmembrane transport
D	0005524	molecular_function	ATP binding
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005758	cellular_component	mitochondrial intermembrane space
D	0005829	cellular_component	cytosol
D	0008320	molecular_function	protein transmembrane transporter activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
D	0034551	biological_process	mitochondrial respiratory chain complex III assembly
D	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
D	0051131	biological_process	chaperone-mediated protein complex assembly
D	0055085	biological_process	transmembrane transport
D	0071806	biological_process	protein transmembrane transport
E	0005524	molecular_function	ATP binding
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005758	cellular_component	mitochondrial intermembrane space
E	0005829	cellular_component	cytosol
E	0008320	molecular_function	protein transmembrane transporter activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
E	0034551	biological_process	mitochondrial respiratory chain complex III assembly
E	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
E	0051131	biological_process	chaperone-mediated protein complex assembly
E	0055085	biological_process	transmembrane transport
E	0071806	biological_process	protein transmembrane transport
F	0005524	molecular_function	ATP binding
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005758	cellular_component	mitochondrial intermembrane space
F	0005829	cellular_component	cytosol
F	0008320	molecular_function	protein transmembrane transporter activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
F	0034551	biological_process	mitochondrial respiratory chain complex III assembly
F	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
F	0051131	biological_process	chaperone-mediated protein complex assembly
F	0055085	biological_process	transmembrane transport
F	0071806	biological_process	protein transmembrane transport
G	0005524	molecular_function	ATP binding
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005758	cellular_component	mitochondrial intermembrane space
G	0005829	cellular_component	cytosol
G	0008320	molecular_function	protein transmembrane transporter activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
G	0034551	biological_process	mitochondrial respiratory chain complex III assembly
G	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
G	0051131	biological_process	chaperone-mediated protein complex assembly
G	0055085	biological_process	transmembrane transport
G	0071806	biological_process	protein transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. TiTFmTTNhpekLDaAIm.R

Chain	Residue	Details
A	THR358-ARG376

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	301
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000305\|PubMed:8599931

Chain	Residue	Details
A	MET1-ASP44
B	MET1-ASP44
C	MET1-ASP44
D	MET1-ASP44
E	MET1-ASP44
F	MET1-ASP44
G	MET1-ASP44

site_id	SWS_FT_FI2
Number of Residues	161
Details	TRANSMEM: Helical => ECO:0000305

Chain	Residue	Details
A	ALA45-ALA68
B	ALA45-ALA68
C	ALA45-ALA68
D	ALA45-ALA68
E	ALA45-ALA68
F	ALA45-ALA68
G	ALA45-ALA68

site_id	SWS_FT_FI3
Number of Residues	2709
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000305\|PubMed:8599931

Chain	Residue	Details
A	ARG69-PHE456
B	ARG69-PHE456
C	ARG69-PHE456
D	ARG69-PHE456
E	ARG69-PHE456
F	ARG69-PHE456
G	ARG69-PHE456

site_id	SWS_FT_FI4
Number of Residues	7
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLY267
B	GLY267
C	GLY267
D	GLY267
E	GLY267
F	GLY267
G	GLY267

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)