Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6SH3

Structure of the ADP state of the heptameric Bcs1 AAA-ATPase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005829	cellular_component	cytosol
A	0008320	molecular_function	protein transmembrane transporter activity
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
A	0034551	biological_process	mitochondrial respiratory chain complex III assembly
A	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
A	0051131	biological_process	chaperone-mediated protein complex assembly
A	0055085	biological_process	transmembrane transport
A	0071806	biological_process	protein transmembrane transport
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005758	cellular_component	mitochondrial intermembrane space
B	0005829	cellular_component	cytosol
B	0008320	molecular_function	protein transmembrane transporter activity
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
B	0034551	biological_process	mitochondrial respiratory chain complex III assembly
B	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
B	0051131	biological_process	chaperone-mediated protein complex assembly
B	0055085	biological_process	transmembrane transport
B	0071806	biological_process	protein transmembrane transport
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005758	cellular_component	mitochondrial intermembrane space
C	0005829	cellular_component	cytosol
C	0008320	molecular_function	protein transmembrane transporter activity
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
C	0034551	biological_process	mitochondrial respiratory chain complex III assembly
C	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
C	0051131	biological_process	chaperone-mediated protein complex assembly
C	0055085	biological_process	transmembrane transport
C	0071806	biological_process	protein transmembrane transport
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005758	cellular_component	mitochondrial intermembrane space
D	0005829	cellular_component	cytosol
D	0008320	molecular_function	protein transmembrane transporter activity
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
D	0034551	biological_process	mitochondrial respiratory chain complex III assembly
D	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
D	0051131	biological_process	chaperone-mediated protein complex assembly
D	0055085	biological_process	transmembrane transport
D	0071806	biological_process	protein transmembrane transport
E	0000166	molecular_function	nucleotide binding
E	0005524	molecular_function	ATP binding
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005758	cellular_component	mitochondrial intermembrane space
E	0005829	cellular_component	cytosol
E	0008320	molecular_function	protein transmembrane transporter activity
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
E	0034551	biological_process	mitochondrial respiratory chain complex III assembly
E	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
E	0051131	biological_process	chaperone-mediated protein complex assembly
E	0055085	biological_process	transmembrane transport
E	0071806	biological_process	protein transmembrane transport
F	0000166	molecular_function	nucleotide binding
F	0005524	molecular_function	ATP binding
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005758	cellular_component	mitochondrial intermembrane space
F	0005829	cellular_component	cytosol
F	0008320	molecular_function	protein transmembrane transporter activity
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
F	0034551	biological_process	mitochondrial respiratory chain complex III assembly
F	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
F	0051131	biological_process	chaperone-mediated protein complex assembly
F	0055085	biological_process	transmembrane transport
F	0071806	biological_process	protein transmembrane transport
G	0000166	molecular_function	nucleotide binding
G	0005524	molecular_function	ATP binding
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005758	cellular_component	mitochondrial intermembrane space
G	0005829	cellular_component	cytosol
G	0008320	molecular_function	protein transmembrane transporter activity
G	0016787	molecular_function	hydrolase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0032979	biological_process	protein insertion into mitochondrial inner membrane from matrix
G	0034551	biological_process	mitochondrial respiratory chain complex III assembly
G	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
G	0051131	biological_process	chaperone-mediated protein complex assembly
G	0055085	biological_process	transmembrane transport
G	0071806	biological_process	protein transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue ADP A 501

Chain	Residue
A	ARG223
A	THR274
A	SER275
A	THR425
A	ALA426
A	GLN429
A	SER227
A	VAL228
A	ILE229
A	PRO269
A	GLY270
A	SER271
A	GLY272
A	LYS273

site_id	AC2
Number of Residues	14
Details	binding site for residue ADP B 501

Chain	Residue
B	ARG223
B	SER227
B	VAL228
B	ILE229
B	PRO269
B	GLY270
B	SER271
B	GLY272
B	LYS273
B	THR274
B	SER275
B	THR425
B	ALA426
B	GLN429

site_id	AC3
Number of Residues	14
Details	binding site for residue ADP C 501

Chain	Residue
C	ARG223
C	SER227
C	VAL228
C	ILE229
C	PRO269
C	GLY270
C	SER271
C	GLY272
C	LYS273
C	THR274
C	SER275
C	THR425
C	ALA426
C	GLN429

site_id	AC4
Number of Residues	14
Details	binding site for residue ADP D 501

Chain	Residue
D	ARG223
D	SER227
D	VAL228
D	ILE229
D	PRO269
D	GLY270
D	SER271
D	GLY272
D	LYS273
D	THR274
D	SER275
D	THR425
D	ALA426
D	GLN429

site_id	AC5
Number of Residues	14
Details	binding site for residue ADP E 501

Chain	Residue
E	ARG223
E	SER227
E	VAL228
E	ILE229
E	PRO269
E	GLY270
E	SER271
E	GLY272
E	LYS273
E	THR274
E	SER275
E	THR425
E	ALA426
E	GLN429

site_id	AC6
Number of Residues	14
Details	binding site for residue ADP F 501

Chain	Residue
F	ARG223
F	SER227
F	VAL228
F	ILE229
F	PRO269
F	GLY270
F	SER271
F	GLY272
F	LYS273
F	THR274
F	SER275
F	THR425
F	ALA426
F	GLN429

site_id	AC7
Number of Residues	13
Details	binding site for residue ADP G 501

Chain	Residue
G	ARG223
G	SER227
G	VAL228
G	ILE229
G	PRO269
G	GLY270
G	SER271
G	LYS273
G	THR274
G	SER275
G	THR425
G	ALA426
G	GLN429

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. TiTFmTTNhpekLDaAIm.R

Chain	Residue	Details
A	THR358-ARG376

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	98
Details	Motif: {"description":"Mitochondrial-targeting signal"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	49
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)