6SDR
W-formate dehydrogenase from Desulfovibrio vulgaris - Oxidized form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0008863 | molecular_function | formate dehydrogenase (NAD+) activity |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0009061 | biological_process | anaerobic respiration |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0030151 | molecular_function | molybdenum ion binding |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0043546 | molecular_function | molybdopterin cofactor binding |
| A | 0045333 | biological_process | cellular respiration |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047111 | molecular_function | formate dehydrogenase (cytochrome-c-553) activity |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0030313 | cellular_component | cell envelope |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | binding site for residue MGD A 1101 |
| Chain | Residue |
| A | LYS90 |
| A | ASP254 |
| A | PRO255 |
| A | ARG256 |
| A | SER272 |
| A | GLY273 |
| A | ASP275 |
| A | ALA404 |
| A | MET405 |
| A | GLY406 |
| A | TRP407 |
| A | SEC192 |
| A | GLY442 |
| A | TYR883 |
| A | ARG884 |
| A | VAL885 |
| A | THR886 |
| A | HIS888 |
| A | TRP889 |
| A | GLN890 |
| A | HIS965 |
| A | LYS996 |
| A | MET225 |
| A | MGD1102 |
| A | H2S1109 |
| A | W1110 |
| A | HOH1349 |
| A | HOH1357 |
| A | HOH1379 |
| A | GLY226 |
| A | SER227 |
| A | ASN228 |
| A | GLU231 |
| A | ASN232 |
| A | VAL253 |
| site_id | AC2 |
| Number of Residues | 32 |
| Details | binding site for residue MGD A 1102 |
| Chain | Residue |
| A | ALA164 |
| A | GLN188 |
| A | ILE191 |
| A | SEC192 |
| A | MET405 |
| A | GLU443 |
| A | TRP551 |
| A | GLY552 |
| A | MET553 |
| A | ASN554 |
| A | GLY558 |
| A | ASN579 |
| A | LEU580 |
| A | CYS608 |
| A | CYS609 |
| A | LYS614 |
| A | ASP641 |
| A | THR882 |
| A | ARG884 |
| A | GLN890 |
| A | THR891 |
| A | LEU893 |
| A | MET894 |
| A | TRP964 |
| A | ASN979 |
| A | THR995 |
| A | LYS996 |
| A | MGD1101 |
| A | H2S1109 |
| A | W1110 |
| A | HOH1260 |
| A | HOH1352 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 A 1103 |
| Chain | Residue |
| A | CYS50 |
| A | TYR52 |
| A | CYS53 |
| A | GLY56 |
| A | CYS57 |
| A | LEU87 |
| A | CYS88 |
| A | LYS90 |
| A | PRO234 |
| A | ILE235 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 1104 |
| Chain | Residue |
| A | ASN228 |
| A | GLU231 |
| A | ARG256 |
| A | ARG259 |
| A | ARG884 |
| A | GLU911 |
| A | ARG946 |
| A | HOH1349 |
| B | HIS39 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue GOL A 1105 |
| Chain | Residue |
| A | TYR300 |
| A | ARG775 |
| A | VAL778 |
| A | ASP779 |
| A | LYS780 |
| A | PRO810 |
| A | GLY811 |
| A | LYS813 |
| A | HIS814 |
| A | PRO815 |
| A | HOH1289 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 1106 |
| Chain | Residue |
| A | GLN447 |
| A | THR450 |
| A | TYR462 |
| A | GOL1107 |
| A | GOL1108 |
| A | HIS193 |
| A | ARG441 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 1107 |
| Chain | Residue |
| A | SER194 |
| A | VAL197 |
| A | THR450 |
| A | LEU455 |
| A | HIS457 |
| A | GOL1106 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 1108 |
| Chain | Residue |
| A | GLY207 |
| A | ALA208 |
| A | TYR462 |
| A | TRP765 |
| A | GOL1106 |
| A | HOH1268 |
| A | HOH1308 |
| A | HOH1494 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue H2S A 1109 |
| Chain | Residue |
| A | SEC192 |
| A | VAL446 |
| A | MGD1101 |
| A | MGD1102 |
| A | W1110 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue W A 1110 |
| Chain | Residue |
| A | SEC192 |
| A | MGD1101 |
| A | MGD1102 |
| A | H2S1109 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 B 301 |
| Chain | Residue |
| B | CYS12 |
| B | THR13 |
| B | ALA14 |
| B | CYS15 |
| B | ARG16 |
| B | CYS18 |
| B | CYS157 |
| B | THR159 |
| B | THR161 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 B 302 |
| Chain | Residue |
| B | CYS74 |
| B | ARG75 |
| B | CYS77 |
| B | PRO81 |
| B | CYS82 |
| B | VAL103 |
| B | CYS121 |
| B | PRO126 |
| B | LYS137 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 B 303 |
| Chain | Residue |
| B | CYS22 |
| B | LYS26 |
| B | LYS51 |
| B | CYS138 |
| B | ASP139 |
| B | MET140 |
| B | CYS141 |
| B | PRO151 |
| B | ALA152 |
| B | CYS153 |
Functional Information from PROSITE/UniProt
| site_id | PS00551 |
| Number of Residues | 19 |
| Details | MOLYBDOPTERIN_PROK_1 Prokaryotic molybdopterin oxidoreductases signature 1. SiCcy.CAVgCgLiVhtakD |
| Chain | Residue | Details |
| A | SER48-ASP66 |
| site_id | PS00932 |
| Number of Residues | 28 |
| Details | MOLYBDOPTERIN_PROK_3 Prokaryotic molybdopterin oxidoreductases signature 3. AklrGIgNgDtVkVsSlrGaleavAiVT |
| Chain | Residue | Details |
| A | ALA917-THR944 |
