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6SDN

Trypanosoma cruzi farnesyl diphosphate synthase in complex with fragment j82

Functional Information from GO Data
ChainGOidnamespacecontents
A0004659molecular_functionprenyltransferase activity
A0008299biological_processisoprenoid biosynthetic process
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue ZN A 401
ChainResidue
AASP98
AASP102
AHOH523
AHOH525
AHOH642

site_idAC2
Number of Residues6
Detailsbinding site for residue ZN A 402
ChainResidue
AHOH673
AHOH737
AASP250
AHOH520
AHOH557
AHOH630

site_idAC3
Number of Residues9
Detailsbinding site for residue 4NC A 403
ChainResidue
APHE50
ATHR54
ATHR212
ATYR213
APHE246
AVAL353
ALYS356
ATHR357
AARG360

site_idAC4
Number of Residues11
Detailsbinding site for residue SO4 A 404
ChainResidue
AGLY47
ALYS48
ATYR49
APHE50
AARG51
AGLN91
AHOH553
AHOH578
AHOH590
AHOH600
AHOH629

Functional Information from PROSITE/UniProt
site_idPS00444
Number of Residues13
DetailsPOLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. IGeyFQVqDDVmD
ChainResidueDetails
AILE242-ASP254

site_idPS00723
Number of Residues15
DetailsPOLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LVeDDim..DgsvmRRG
ChainResidueDetails
ALEU95-GLY109

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PDB entries from 2024-07-24

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